(Q37762157)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20517295%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

review article

1 reference

title

Pathogenesis of ankylosing spondylitis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20517295%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

0 references

1

1 reference

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4 February 2020

author name string

Jieruo Gu

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20517295%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

David Yu

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20517295%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

language of work or name

English

0 references

publication date

1 June 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20517295%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Rheumatology

4 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20517295%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20517295%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20517295%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

page(s)

399-405

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20517295%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrrheum.2010.79

4 February 2020

exact match

0 references

cites work

Adalimumab, etanercept and infliximab for the treatment of ankylosing spondylitis: a systematic review and economic evaluation

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

High Association of an HL-A Antigen, W27, with Ankylosing Spondylitis

21 January 2018

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Epidemiology of HLA-B27 and Arthritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Conformational dimorphism of self-peptides and molecular mimicry in a disease-associated HLA-B27 subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

21 January 2018

Ankylosing spondylitis

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Concepts and epidemiology of spondyloarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

A systematic MEDLINE analysis of therapeutic approaches in ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

ASAS/EULAR recommendations for the management of ankylosing spondylitis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Tumour necrosis factor blockers and structural remodelling in ankylosing spondylitis: what is reality and what is fiction?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Radiographic findings following two years of infliximab therapy in patients with ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Radiographic progression of ankylosing spondylitis after up to two years of treatment with etanercept.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Ankylosing spondylitis and HL-A 27.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Destructive lesions of vertebral bodies in ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Immunohistologic analysis of zygapophyseal joints in patients with ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Immunohistochemical analysis of hip arthritis in ankylosing spondylitis: evaluation of the bone-cartilage interface and subchondral bone marrow

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Immunohistological examination of open sacroiliac biopsies of patients with ankylosing spondylitis: detection of tumour necrosis factor alpha in two patients with early disease and transforming growth factor beta in three more advanced cases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

The anatomical basis for disease localisation in seronegative spondyloarthropathy at entheses and related sites

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Diagnostic classification of spondylarthropathy and rheumatoid arthritis by synovial histopathology: a prospective study in 154 consecutive patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Association of CD163+ macrophages and local production of soluble CD163 with decreased lymphocyte activation in spondylarthropathy synovitis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Absence of a classically activated macrophage cytokine signature in peripheral spondylarthritis, including psoriatic arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Tumor necrosis factor antagonist mechanisms of action: a comprehensive review

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Susceptibility to ankylosing spondylitis in twins the role of genes, HLA, and the environment

31 March 2020

2 references

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

31 March 2020

12 December 2020

Recurrence risk modelling of the genetic susceptibility to ankylosing spondylitis

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

An Aminopeptidase, ARTS-1, Is Required for Interleukin-6 Receptor Shedding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Genetics and genomics of ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

The interleukin-23/interleukin-17 axis in spondyloarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

IL-17 as a future therapeutic target for rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human beta 2m: an animal model of HLA-B27-associated human disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

HLA-B27 transgenic rat: an animal model mimicking gut and joint involvement in human spondyloarthritides

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Inflammatory disease in HLA-B27 transgenic rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Genetics and the pathogenesis of ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Recent studies on the genetic basis of ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Subtypes of HLA-B27: history and implications in the pathogenesis of ankylosing spondylitis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Crystallization and preliminary X-ray diffraction studies of the human major histocompatibility antigen HLA-B27

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Major histocompatibility complex class I-restricted antigen processing and presentation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

ER quality control in the biogenesis of MHC class I molecules

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: Implications for the pathogenesis of spondylarthritis-like disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

HLA-B27 misfolding and spondyloarthropathies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-beta induction via X-box binding protein 1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Upregulation of 78-kDa glucose-regulated protein in macrophages in peripheral joints of active ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

HLA-B27 and the pathogenesis of spondyloarthropathies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

HLA-B27-restricted CD8+ T cell response to cartilage-derived self peptides in ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

CD8(+) T-cell autoreactivity to an HLA-B27-restricted self-epitope correlates with ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Analysis of the CD8+ T cell response to the G1 domain of aggrecan in ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

The role of B27 heavy chain dimer immune receptor interactions in spondyloarthritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Cell-surface expression and immune receptor recognition of HLA-B27 homodimers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Expansion and enhanced survival of natural killer cells expressing the killer immunoglobulin-like receptor KIR3DL2 in spondylarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

The HLA-B27 peptidome: building on the cornerstone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Dual, HLA-B27 Subtype-dependent Conformation of a Self-peptide

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Spondylarthritis in the absence of B lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Rituximab in the spondyloarthropathies: data of eight patients followed up in the French Autoimmunity and Rituximab (AIR) registry

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Transfer of the inflammatory disease of HLA-B27 transgenic rats by bone marrow engraftment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

CD8 alpha beta T cells are not essential to the pathogenesis of arthritis or colitis in HLA-B27 transgenic rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Spondylarthritis in HLA-B27/human beta2-microglobulin-transgenic rats is not prevented by lack of CD8.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Dendritic cells from spondylarthritis-prone HLA-B27-transgenic rats display altered cytoskeletal dynamics, class II major histocompatibility complex expression, and viability.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Correlation between dendritic cell functional defect and spondylarthritis phenotypes in HLA-B27/HUMAN beta2-microglobulin-transgenic rat lines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Basic concepts of enthesis biology and immunology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Microdamage and altered vascularity at the enthesis-bone interface provides an anatomic explanation for bone involvement in the HLA-B27-associated spondylarthritides and allied disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

The interplay between the geographic distribution of HLA-B27 alleles and their role in infectious and autoimmune diseases: a unifying hypothesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Ankylosing spondylitis is linked to Klebsiella--the evidence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Reactive arthritis or post-infectious arthritis?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Mechanisms of disease: infection and spondyloarthritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Use of immunohistologic and in situ hybridization techniques in the examination of sacroiliac joint biopsy specimens from patients with ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Radiographic changes in rheumatoid arthritis patients attaining different disease activity states with methotrexate monotherapy and infliximab plus methotrexate: the impacts of remission and tumour necrosis factor blockade

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Disease modification in ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Expression of cathepsin K and matrix metalloproteinase 1 indicate persistent osteodestructive activity in long-standing ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Bone remodeling in rheumatic disease: a question of balance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Progress in spondylarthritis. Mechanisms of new bone formation in spondyloarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Bone morphogenetic protein signaling in joint homeostasis and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Noggin and sclerostin bone morphogenetic protein antagonists form a mutually inhibitory complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

The role of Wnt proteins in arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Dickkopf-1 is a master regulator of joint remodeling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

Evidence that Dkk-1 is dysfunctional in ankylosing spondylitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.79

31 March 2020

The HLA-B*2705 peptidome

1 reference

12 December 2020

T cells, but not thymic exposure to HLA-B27, are required for the inflammatory disease of HLA-B27 transgenic rats.

1 reference

12 December 2020

The enthesis organ concept and its relevance to the spondyloarthropathies

1 reference

12 December 2020

Clues to pathogenesis of spondyloarthropathy derived from synovial fluid mononuclear cell gene expression profiles

1 reference

12 December 2020

Evidence for the prevention of enthesitis in HLA-B27/hβ(2)m transgenic rats treated with a monoclonal antibody against TNF-α.

1 reference

12 December 2020

MHC class I-peptide interactions and TCR recognition

1 reference

12 December 2020

Identification of cytokines that might enhance the promoter activity of HLA-B27.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2010.79

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20517295%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference