(Q37764002)

22 August 2017

1 reference

title

Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation (English)

1 reference

22 August 2017

1 reference

Rachel L Rutishauser

1

1 reference

PubMed ID

20536566

22 August 2017

Susan M Kaech

series ordinal

2

1 reference

22 August 2017

1 May 2010

1 reference

22 August 2017

Immunological Reviews

1 reference

22 August 2017

235

1 reference

22 August 2017

1

1 reference

22 August 2017

219-233

1 reference

Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection

22 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

CD8 T cell dysfunction during chronic viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Bcl6 mediates the development of T follicular helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Signals required for programming effector and memory development by CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

CD8 regulatory T cells: what's old is now new.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Regulating functional cell fates in CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Distinct regulation of effector and memory T-cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Pathways of memory CD8+ T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Activation changes the spectrum but not the diversity of genes expressed by T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Augmentation in expression of activation-induced genes differentiates memory from naive CD4+ T cells and is a molecular mechanism for enhanced cellular response of memory CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Molecular and functional profiling of memory CD8 T cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Functional properties and lineage relationship of CD8+ T cell subsets identified by expression of IL-7 receptor alpha and CD62L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

IL-12 signaling drives CD8+ T cell IFN-gamma production and differentiation of KLRG1+ effector subpopulations during Toxoplasma gondii Infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Manipulating the rate of memory CD8+ T cell generation after acute infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Lineage relationship and protective immunity of memory CD8 T cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Cutting edge: increased expression of Bcl-2 in antigen-specific memory CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

CD8+ T cell contraction is controlled by early inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Expression of killer cell lectin-like receptor G1 on antigen-specific human CD8+ T lymphocytes during active, latent, and resolved infection and its relation with CD57

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Activation phenotype, rather than central- or effector-memory phenotype, predicts the recall efficacy of memory CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Viral infections induce abundant numbers of senescent CD8 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Effector CD8 T cell development: a balancing act between memory cell potential and terminal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Human CD8(+) T-cell differentiation in response to viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

CD8 T cell recall responses are regulated by the tissue tropism of the memory cell and pathogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Differential contributions of central and effector memory T cells to recall responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Cutting edge: migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Cutting edge: latecomer CD8 T cells are imprinted with a unique differentiation program

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Plasticity of CD4+ T cell lineage differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

The functional plasticity of T cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Modelling T-cell memory by genetic marking of memory T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

A transgenic mouse model genetically tags all activated CD8 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Secondary replicative function of CD8+ T cells that had developed an effector phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Shortening the infectious period does not alter expansion of CD8 T cells but diminishes their capacity to differentiate into memory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Central memory and effector memory T cell subsets: function, generation, and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Runx and ThPOK: a balancing act to regulate thymocyte lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Multilineage transcriptional priming and determination of alternate hematopoietic cell fates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Early programming of T cell populations responding to bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Augmentation of effector CD8+ T cell generation with enhanced granzyme B expression by IL-27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

A novel transcription factor, T-bet, directs Th1 lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Antigen-driven effector CD8 T cell function regulated by T-bet

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon gamma production from CD4(+) versus CD8(+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Notch regulates cytolytic effector function in CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

STAT5-mediated signals sustain a TCR-initiated gene expression program toward differentiation of CD8 T cell effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Bcl6 controls granzyme B expression in effector CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Blimp-1 transcription factor is required for the differentiation of effector CD8(+) T cells and memory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Effector T-cell differentiation during viral and bacterial infections: Role of direct IL-12 signals for cell fate decision of CD8(+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

B and T lymphocyte attenuator regulates CD8+ T cell-intrinsic homeostasis and memory cell generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

The mTOR kinase determines effector versus memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and Eomesodermin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

mTOR regulates memory CD8 T-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Transcriptional regulator Id2 mediates CD8+ T cell immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Blimp1 is a critical determinant of the germ cell lineage in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Serine protease inhibitor 2A is a protective factor for memory T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Regulation and functions of Blimp-1 in T and B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Endoplasmic reticulum stress regulator XBP-1 contributes to effector CD8+ T cell differentiation during acute infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Control of homeostasis of CD8+ memory T cells by opposing cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Overexpression of IL-21 promotes massive CD8+ memory T cell accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

CD27 mediates interleukin-2-independent clonal expansion of the CD8+ T cell without effector differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Mature T cells depend on signaling through the IKK complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Kruppel-like factor 2 regulates thymocyte and T-cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Krüppel-like factors KLF4 and KLF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Transcriptional regulation of mouse L-selectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Role for Bcl-6 in the generation and maintenance of memory CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Bcl6 acts as an amplifier for the generation and proliferative capacity of central memory CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Impaired memory CD8 T cell development in the absence of methyl-CpG-binding domain protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Bmi-1, stem cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Loss of T cell receptor-induced Bmi-1 in the KLRG1(+) senescent CD8(+) T lymphocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

The expansion and maintenance of antigen-selected CD8(+) T cell clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

Suppression of IL7Rα Transcription by IL-7 and Other Prosurvival Cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2010.00901.X

10.1111/J.0105-2896.2010.00901.X

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20536566