(Q37764795)

22 August 2017

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title

Generation, function, and prognostic utility of somatic mitochondrial DNA mutations in cancer (English)

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22 August 2017

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Mariola Kulawiec

1

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22 August 2017

Jesse J Salk

2

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22 August 2017

Nolan G Ericson

3

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22 August 2017

Jonathan Wanagat

4

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22 August 2017

Jason H Bielas

5

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22 August 2017

1 June 2010

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Environmental and Molecular Mutagenesis

22 August 2017

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22 August 2017

51

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22 August 2017

5

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22 August 2017

427-439

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Assessment of plasma DNA levels, allelic imbalance, and CA 125 as diagnostic tests for cancer

22 August 2017

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Analysis of mitochondrial DNA mutations in D-loop region in thyroid lesions.

21 January 2018

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Clonal expansion of different mtDNA variants without selective advantage in solid tumors

21 January 2018

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Identification of somatic and germline mitochondrial DNA sequence variants in prostate cancer patients

21 January 2018

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Cancer cell mitochondria confer apoptosis resistance and promote metastasis

21 January 2018

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Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma

21 January 2018

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Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors

21 January 2018

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Impact of platinum on the whole mitochondrial genome of ovarian carcinomas both in vivo and in vitro

21 January 2018

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Preferential alkylation of mitochondrial deoxyribonucleic acid by N-methyl-N-nitrosourea

21 January 2018

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Levels of circulating cell-free nuclear and mitochondrial DNA in benign and malignant ovarian tumors.

21 January 2018

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Mitochondrial A135149 mutation without MELAS but in association with papillary thyroid carcinoma

21 January 2018

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7 January 2021

High frequency of somatic mitochondrial DNA mutations in human thyroid carcinomas and complex I respiratory defect in thyroid cancer cell lines.

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7 January 2021

Covalent binding of polycyclic aromatic compounds to mitochondrial and nuclear DNA.

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7 January 2021

Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis

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7 January 2021

Cigarette smoking induces an increase in oxidative DNA damage, 8-hydroxydeoxyguanosine, in a central site of the human lung

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7 January 2021

Human cancers express a mutator phenotype

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7 January 2021

Quantification of random genomic mutations.

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7 January 2021

Limited clinical relevance of mitochondrial DNA mutation and gene expression analyses in ovarian cancer

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7 January 2021

Mitochondrial DNA mutations in human cancer

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7 January 2021

High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection

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7 January 2021

A novel mtDNA mutation in the ND5 subunit of complex I in two MELAS patients

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7 January 2021

Transgenic mouse mutation assay systems can play an important role in regulatory mutagenicity testing in vivo for the detection of site-of-contact mutagens

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7 January 2021

Apoptotic DNA fragments in serum of patients with muscle invasive bladder cancer: a prognostic entity.

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7 January 2021

Cell-free circulating DNA: diagnostic value in patients with testicular germ cell cancer

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7 January 2021

Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

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7 January 2021

Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma

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7 January 2021

Circulating free DNA in plasma or serum as biomarker of carcinogenesis: practical aspects and biological significance

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7 January 2021

Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability

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7 January 2021

Detection of mitochondrial DNA alterations in primary tumors and corresponding serum of colorectal cancer patients

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7 January 2021

Novel mitochondrial DNA deletion found in a renal cell carcinoma

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7 January 2021

Quantitative analysis of plasma circulating DNA at diagnosis and during follow-up of breast cancer patients.

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7 January 2021

Tandem duplication/triplication correlated with poly-cytosine stretch variation in human mitochondrial DNA D-loop region

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7 January 2021

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis

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7 January 2021

The mitochondrial theory of aging: dead or alive?

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7 January 2021

Oxidative DNA base damage and antioxidant enzyme activities in human lung cancer

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7 January 2021

Mitochondrial mutations in early stage prostate cancer and bodily fluids

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7 January 2021

Relationship between mitochondrial DNA mutations and clinical characteristics in human lung cancer

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7 January 2021

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

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7 January 2021

Increased cell-free DNA in plasma of patients with metastatic spread in prostate cancer

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7 January 2021

Mitochondrial mutational spectra in human cells and tissues

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7 January 2021

Somatic mutations of mitochondrial DNA in digestive tract cancers

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7 January 2021

Mitochondrial genome instability and mtDNA depletion in human cancers

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7 January 2021

Clinical value of mitochondrial mutations in colorectal cancer.

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7 January 2021

High frequency of mitochondrial genome instability in human endometrial carcinomas.

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7 January 2021

Homoplasmic MELAS A3243G mtDNA mutation in a colon cancer sample

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7 January 2021

Mitochondrial D-Loop instability in thyroid tumours is not a marker of malignancy

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7 January 2021

Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma

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7 January 2021

Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

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7 January 2021

Isolation of rare circulating tumour cells in cancer patients by microchip technology

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7 January 2021

Somatic mitochondrial DNA mutations in human chromophobe renal cell carcinomas

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7 January 2021

Preferential attack of mitochondrial DNA by aflatoxin B1 during hepatocarcinogenesis

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7 January 2021

Detection, clinical relevance and specific biological properties of disseminating tumour cells

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7 January 2021

Somatic mitochondrial DNA mutations in prostate cancer and normal appearing adjacent glands in comparison to age-matched prostate samples without malignant histology

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7 January 2021

Genotypic selection methods for the direct analysis of point mutations

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7 January 2021

Somatic D-loop mitochondrial DNA mutations are frequent in uterine serous carcinoma

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7 January 2021

mtDNA mutations increase tumorigenicity in prostate cancer

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7 January 2021

Mitochondrial DNA instability in malignant melanoma of the skin is mostly restricted to nodular and metastatic stages

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7 January 2021

Somatic mutations of the mitochondrial genome in human colorectal tumours

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7 January 2021

A critical reassessment of the role of mitochondria in tumorigenesis

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7 January 2021

Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis.

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7 January 2021

The consensus coding sequences of human breast and colorectal cancers

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7 January 2021

Detection of mitochondrial DNA alterations in plasma of malignant melanoma patients

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7 January 2021

Mitochondrial DNA alterations in thyroid cancer

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7 January 2021

Circulating nucleosomes and response to chemotherapy: an in vitro, in vivo and clinical study on cervical cancer patients

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7 January 2021

Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer

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7 January 2021

Increased integrity of free circulating DNA in sera of patients with colorectal or periampullary cancer: direct quantitative PCR for ALU repeats

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7 January 2021

Somatic mitochondrial DNA mutations in primary and metastatic ovarian cancer

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7 January 2021

Mitochondrial point mutations do not limit the natural lifespan of mice.

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7 January 2021

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice

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7 January 2021

Mitochondrial diseases in man and mouse

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7 January 2021

Somatic mutations of mitochondrial genome in early stage breast cancer

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7 January 2021

Detection of mosaic pattern of mitochondrial DNA alterations in different populations of cells from the same endometrial tumor.

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7 January 2021

Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer

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7 January 2021

Cell-free DNA: measurement in various carcinomas and establishment of normal reference range

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7 January 2021

Studies on nitrosodimethylamine: preferential methylation of mitochondrial DNA in rats and hamsters

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7 January 2021

Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours.

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7 January 2021

Fen1 mutations result in autoimmunity, chronic inflammation and cancers

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7 January 2021

Mitochondrial DNA mutations in breast cancer tissue and in matched nipple aspirate fluid

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7 January 2021

Identifiers

DOI

10.1002/EM.20582

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22 August 2017

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