(Q37764890)

22 August 2017

1 reference

title

Bone morphogenetic protein and growth differentiation factor cytokine families and their protein antagonists (English)

1 reference

22 August 2017

1 reference

Christopher C Rider

1

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22 August 2017

Barbara Mulloy

series ordinal

2

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22 August 2017

language of work or name

English

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publication date

1 July 2010

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22 August 2017

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22 August 2017

volume

429

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22 August 2017

issue

1

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22 August 2017

page(s)

1-12

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Role of morphogenetic proteins in skeletal tissue engineering and regeneration

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Use of Bmp1/Tll1 doubly homozygous null mice and proteomics to identify and validate in vivo substrates of bone morphogenetic protein 1/tolloid-like metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Identification of a Novel Member (GDF-1) of the Transforming Growth Factor-β Superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Evolutionary trace analysis of TGF-beta and related growth factors: implications for site-directed mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Crystal structure of BMP-9 and functional interactions with pro-region and receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The family of bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

An integrated functional genomics screening program reveals a role for BMP-9 in glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

BMP10 is essential for maintaining cardiac growth during murine cardiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Growth differentiation factor 9 is a germ cell regulator of Sertoli cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Genomic analyses facilitate identification of receptors and signalling pathways for growth differentiation factor 9 and related orphan bone morphogenetic protein/growth differentiation factor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Structure of the ternary signaling complex of a TGF-beta superfamily member

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Molecular recognition of BMP-2 and BMP receptor IA

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

A single residue of GDF-5 defines binding specificity to BMP receptor IB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Developmental expression of mouse Follistatin-like 1 (Fstl1): Dynamic regulation during organogenesis of the kidney and lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Differential actions of follistatin and follistatin-like 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Crystal structures of the heparan sulfate-binding domain of follistatin. Insights into ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Characterization of unique binding kinetics of follistatin and activin or inhibin in serum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Follistatin inhibits the function of the oocyte-derived factor BMP-15

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Bone morphogenetic protein (BMP) ligands and receptors in bovine ovarian follicle cells: actions of BMP-4, -6 and -7 on granulosa cells and differential modulation of Smad-1 phosphorylation by follistatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Biological activity of follistatin isoforms and follistatin-like-3 is dependent on differential cell surface binding and specificity for activin, myostatin, and bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The role of activins and follistatins in skin and hair follicle development and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Opposing effects of activin A and follistatin on developing skeletal muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Role of follistatin in promoting adipogenesis in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Follistatin-like protein 1 promotes arthritis by up-regulating IFN-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Active cell migration drives the unilateral movements of the anterior visceral endoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The Mouse Cer1 (Cerberus related or homologue) Gene Is Not Required for Anterior Pattern Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Coding sequence and expression patterns of mouse chordin and mapping of the cognate mouse chrd and human CHRD genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The left-right axis is regulated by the interplay of Coco, Xnr1 and derrière in Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

DAN directs endolymphatic sac and duct outgrowth in the avian inner ear.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Expression of the BMP antagonist Dan during murine forebrain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Mutation and analysis of Dan, the founding member of the Dan family of transforming growth factor beta antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Identification of drm, a novel gene whose expression is suppressed in transformed cells and which can inhibit growth of normal but not transformed cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Bone morphogenetic protein-4 inhibitor gremlin is overexpressed in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The role of gremlin, a BMP antagonist, and epithelial-to-mesenchymal transition in proliferative vitreoretinopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Angiopoietin-1 mediates the proangiogenic activity of the bone morphogenic protein antagonist Drm

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Cutting edge: bone morphogenetic protein antagonists Drm/Gremlin and Dan interact with Slits and act as negative regulators of monocyte chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Patient demographics as a predictor of the ten-year survival rate in primary total knee replacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The bone morphogenetic protein antagonist noggin regulates mammalian cardiac morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Noggin regulates Bmp4 activity during pituitary induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Noggin is required for normal lobe patterning and ductal budding in the mouse prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Bmp4 and Noggin expression during early thymus and parathyroid organogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Human oligodendrocytes derived from embryonic stem cells: Effect of noggin on phenotypic differentiation in vitro and on myelination in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Derivation of neural precursors from human embryonic stem cells in the presence of noggin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Noggin enhances dopamine neuron production from human embryonic stem cells and improves behavioral outcome after transplantation into Parkinsonian rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Noggin expands neural stem cells in the adult hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Lack of noggin expression by cancer cells is a determinant of the osteoblast response in bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Sequence and expression of a novel mouse gene PRDC (protein related to DAN and cerberus) identified by a gene trap approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

SOST/sclerostin, an osteocyte-derived negative regulator of bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

A short treatment with an antibody to sclerostin can inhibit bone loss in an ongoing model of colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Characterization of the Structural Features and Interactions of Sclerostin: MOLECULAR INSIGHT INTO A KEY REGULATOR OF Wnt-MEDIATED BONE FORMATION

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Noggin and sclerostin bone morphogenetic protein antagonists form a mutually inhibitory complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Homologues of Twisted gastrulation are extracellular cofactors in antagonism of BMP signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Twisted gastrulation is a conserved extracellular BMP antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Twisted gastrulation can function as a BMP antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Twisted gastrulation is required for forebrain specification and cooperates with Chordin to inhibit BMP signaling during X. tropicalis gastrulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Uterine sensitization-associated gene-1: a novel gene induced within the rat endometrium at the time of uterine receptivity/sensitization for the decidual cell reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Characterization of wise protein and its molecular mechanism to interact with both Wnt and BMP signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Structural basis of BMP signalling inhibition by the cystine knot protein Noggin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

NMR structure of the Wnt modulator protein Sclerostin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The organizer factors Chordin and Noggin are required for mouse forebrain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

A generalized skeletal hyperostosis in two siblings caused by a novel mutation in the SOST gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

A Known SOST Gene Mutation Causes Sclerosteosis in a Familial and an Isolated Case from Brazilian Origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Human bone morphogenetic protein 2 contains a heparin-binding site which modifies its biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Action range of BMP is defined by its N-terminal basic amino acid core

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Biochemical and biophysical characterization of refolded Drosophila DPP, a homolog of bone morphogenetic proteins 2 and 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

glypican-3 controls cellular responses to Bmp4 in limb patterning and skeletal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Heparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Heparin potentiates the in vivo ectopic bone formation induced by bone morphogenetic protein-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Disruption of heparan and chondroitin sulfate signaling enhances mesenchymal stem cell-derived osteogenic differentiation via bone morphogenetic protein signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Endogenous heparan sulfate and heparin modulate bone morphogenetic protein-4 signaling and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Enhancement of ectopic bone formation by bone morphogenetic protein-2 released from a heparin-conjugated poly(L-lactic-co-glycolic acid) scaffold.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Heparin/heparan sulphate binding in the TGF-beta cytokine superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Heparan sulfate is required for bone morphogenetic protein-7 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Domain-specific modification of heparan sulfate by Qsulf1 modulates the binding of the bone morphogenetic protein antagonist Noggin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Multiple defects and perinatal death in mice deficient in follistatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Granulosa cell-specific inactivation of follistatin causes female fertility defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

FSTL3 deletion reveals roles for TGF-beta family ligands in glucose and fat homeostasis in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Overexpression of follistatin-like 3 in gonads causes defects in gonadal development and function in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Conditional deletion of gremlin causes a transient increase in bone formation and bone mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Skeletal overexpression of gremlin impairs bone formation and causes osteopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Mammalian twisted gastrulation is essential for skeleto-lymphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Enhanced osteoclastogenesis causes osteopenia in twisted gastrulation-deficient mice through increased BMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Crystal structure of the BMP-2-BRIA ectodomain complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Crystal structure of recombinant human growth and differentiation factor 5: evidence for interaction of the type I and type II receptor-binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Skeletal Overexpression of Noggin Results in Osteopenia and Reduced Bone Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

Twisted gastrulation, a bone morphogenetic protein agonist/antagonist, is not required for post-natal skeletal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

On the wings of inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100305

21 January 2018

Identifiers

DOI

10.1042/BJ20100305

1 reference

22 August 2017

1 reference