(Q37766391)

22 August 2017

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title

Inbred strains should replace outbred stocks in toxicology, safety testing, and drug development (English)

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22 August 2017

Michael F W Festing

1

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22 August 2017

language of work or name

English

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publication date

18 June 2010

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22 August 2017

published in

Toxicologic Pathology

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22 August 2017

volume

38

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22 August 2017

issue

5

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22 August 2017

page(s)

681-690

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Genetic variation and population substructure in outbred CD-1 mice: implications for genome-wide association studies

22 August 2017

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Differential ethanol intake in Tryon maze-bright and Tryon maze-dull rats: implications for the validity of the animal model of selectively bred rats for high ethanol consumption

21 January 2018

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21 January 2018

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21 January 2018

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Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies

21 January 2018

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21 January 2018

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Improving toxicity screening and drug development by using genetically defined strains

21 January 2018

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Strain differences in haematological response to chloramphenicol succinate in mice: implications for toxicological research

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Characterization of an inbred strain of the SENCAR mouse that is highly sensitive to phorbol esters

21 January 2018

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A sequence-based variation map of 8.27 million SNPs in inbred mouse strains

21 January 2018

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A toxicology for the 21st century--mapping the road ahead

21 January 2018

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Statistical design of toxicity assays: Role of genetic structure of test animal population

21 January 2018

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Marked strain differences in the pharmacokinetics of an alpha4beta1 integrin antagonist, 4-[1-[3-Chloro-4-[N-(2-methylphenyl)-ureido]phenylacetyl]-(4S)-fluoro-(2S)-pyrrolidine-2-yl]-methoxybenzoic Acid (D01-4582), in Sprague-Dawley rats are associat

21 January 2018

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A set of highly informative rat simple sequence length polymorphism (SSLP) markers and genetically defined rat strains

21 January 2018

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The expanding role of mouse genetics for understanding human biology and disease

21 January 2018

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Fat, frail and dying young: survival, body weight and pathology of the Charles River Sprague-Dawley-derived rat prior to and since the introduction of the VAFR variant in 1988.

21 January 2018

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An efficient SNP system for mouse genome scanning and elucidating strain relationships.

21 January 2018

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Principles of safety pharmacology

21 January 2018

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Low-dose effects of bisphenol A: a serious threat to human health?

21 January 2018

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Genetic variation in coding regions between and within commonly used inbred rat strains

21 January 2018

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Analysis of two inbred strains of mice derived from the SENCAR stock with different susceptibility to skin tumor progression.

21 January 2018

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Quiet mutations in inbred strains of mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/0192623310373776

1 reference

22 August 2017

1 reference