(Q37771890)

22 August 2017

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title

betaARKct: a therapeutic approach for improved adrenergic signaling and function in heart disease (English)

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22 August 2017

Henriette Brinks

1

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22 August 2017

Walter J Koch

series ordinal

2

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22 August 2017

language of work or name

English

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publication date

10 July 2010

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Journal of Cardiovascular Translational Research

22 August 2017

published in

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22 August 2017

volume

3

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22 August 2017

issue

5

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22 August 2017

page(s)

499-506

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The myocardial beta-adrenergic system in spontaneously hypertensive heart failure (SHHF) rats.

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12265-010-9206-6

In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12265-010-9206-6

Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12265-010-9206-6

G-Protein-coupled receptor kinase activity in hypertension : increased vascular and lymphocyte G-protein receptor kinase-2 protein expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12265-010-9206-6

Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by beta-adrenergic receptor stimulation and blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12265-010-9206-6

Comparative hemodynamic, left ventricular functional, and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12265-010-9206-6

Arrestins as signaling molecules involved in apoptotic pathways: a real eye opener

21 January 2018

1 reference

12 December 2020

Overexpression of the cardiac beta(2)-adrenergic receptor and expression of a beta-adrenergic receptor kinase-1 (betaARK1) inhibitor both increase myocardial contractility but have differential effects on susceptibility to ischemic injury

1 reference

12 December 2020

Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury

1 reference

12 December 2020

Adenylyl cyclase and G protein receptor kinase expression during development of heart failure.

1 reference

12 December 2020

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

1 reference

12 December 2020

Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling.

1 reference

12 December 2020

Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction

1 reference

12 December 2020

The β-adrenergic receptor kinase in heart failure

1 reference

12 December 2020

The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor

1 reference

12 December 2020

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

1 reference

12 December 2020

Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt.

1 reference

12 December 2020

Cardiac gene therapy: optimization of gene delivery techniques in vivo

1 reference

12 December 2020

Level of beta-adrenergic receptor kinase 1 inhibition determines degree of cardiac dysfunction after chronic pressure overload-induced heart failure

1 reference

12 December 2020

Reversal of impaired myocardial beta-adrenergic receptor signaling by continuous-flow left ventricular assist device support

1 reference

12 December 2020

In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function

1 reference

12 December 2020

G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure

1 reference

12 December 2020

Adenovirus-mediated gene transfer of the beta2-adrenergic receptor to donor hearts enhances cardiac function

1 reference

12 December 2020

Molecular signature of recovery following combination left ventricular assist device (LVAD) support and pharmacologic therapy.

1 reference

12 December 2020

Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection.

1 reference

12 December 2020

Left ventricular assist device and drug therapy for the reversal of heart failure

1 reference

12 December 2020

Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice

1 reference

12 December 2020

Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure

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12 December 2020

G protein-coupled receptor kinase 2 expression and activity are associated with blood pressure in black Americans

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12 December 2020

Overexpression of G protein-coupled receptor kinase-2 in smooth muscle cells reduces neointimal hyperplasia

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12 December 2020

Myocardial adeno-associated virus serotype 6-betaARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure

1 reference

12 December 2020

Myocardial gene transfer and overexpression of beta2-adrenergic receptors potentiates the functional recovery of unloaded failing hearts

1 reference

12 December 2020

Role and possible mechanisms of clenbuterol in enhancing reverse remodelling during mechanical unloading in murine heart failure

1 reference

12 December 2020

The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase

1 reference

12 December 2020

Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery

1 reference

12 December 2020

Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor

1 reference

12 December 2020

Regulation of myocardial betaARK1 expression in catecholamine-induced cardiac hypertrophy in transgenic mice overexpressing alpha1B-adrenergic receptors

1 reference

12 December 2020

Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial.

1 reference

12 December 2020

G protein-coupled receptor kinases

1 reference

12 December 2020

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

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12 December 2020

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

1 reference

12 December 2020

Protein kinases that phosphorylate activated G protein-coupled receptors.

1 reference

12 December 2020

Mechanical unloading restores beta-adrenergic responsiveness and reverses receptor downregulation in the failing human heart

1 reference

12 December 2020

Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function

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12 December 2020

Activation of beta-adrenergic receptor kinase during myocardial ischemia

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12 December 2020

Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure

1 reference

12 December 2020

Ventricular dysfunction after cardioplegic arrest is improved after myocardial gene transfer of a beta-adrenergic receptor kinase inhibitor

1 reference

12 December 2020

Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts

1 reference

12 December 2020

Lymphocyte levels of GRK2 (betaARK1) mirror changes in the LVAD-supported failing human heart: lower GRK2 associated with improved beta-adrenergic signaling after mechanical unloading.

1 reference

12 December 2020

Acute ischemic cardiac dysfunction is attenuated via gene transfer of a peptide inhibitor of the beta-adrenergic receptor kinase (betaARK1)

1 reference

12 December 2020

Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure

1 reference

12 December 2020

Myocardial overexpression of adrenergic receptors and receptor kinases

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12 December 2020

Defective beta-adrenergic receptor signaling precedes the development of dilated cardiomyopathy in transgenic mice with calsequestrin overexpression

1 reference

12 December 2020

Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy

1 reference

12 December 2020

G-protein-coupled receptor kinase activity is increased in hypertension

1 reference

12 December 2020

10.1007/S12265-010-9206-6

Identifiers

DOI

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22 August 2017

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