(Q37772901)

22 August 2017

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title

DNA methylation in cell differentiation and reprogramming: an emerging systematic view (English)

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22 August 2017

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2

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22 August 2017

Kevin Huang

1

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22 August 2017

publication date

1 July 2010

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22 August 2017

published in

Regenerative Medicine

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22 August 2017

volume

5

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22 August 2017

issue

4

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22 August 2017

page(s)

531-544

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Stability and flexibility of epigenetic gene regulation in mammalian development

22 August 2017

cites work

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DNA methylation: the nuts and bolts of repression

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

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A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

21 January 2018

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Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci

21 January 2018

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Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases

21 January 2018

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Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.

21 January 2018

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Preference of DNA methyltransferases for CpG islands in mouse embryonic stem cells

21 January 2018

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Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons.

21 January 2018

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Epigenetic reprogramming and induced pluripotency

21 January 2018

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

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Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

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Worms gang up on bacteria

21 January 2018

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CpG islands in vertebrate genomes

21 January 2018

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Comprehensive analysis of CpG islands in human chromosomes 21 and 22

21 January 2018

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Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.

21 January 2018

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Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation

21 January 2018

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Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

21 January 2018

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Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

21 January 2018

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A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters

21 January 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

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DNA methylation landscapes: provocative insights from epigenomics

21 January 2018

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Gene body-specific methylation on the active X chromosome

21 January 2018

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Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

21 January 2018

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Human DNA methylomes at base resolution show widespread epigenomic differences

21 January 2018

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Dynamic changes in the human methylome during differentiation

21 January 2018

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Developmental programming of CpG island methylation profiles in the human genome

21 January 2018

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Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells

21 January 2018

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DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

21 January 2018

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Active demethylation of the paternal genome in the mouse zygote

21 January 2018

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Chromosome methylation patterns during mammalian preimplantation development

21 January 2018

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Dynamic reprogramming of DNA methylation in the early mouse embryo.

21 January 2018

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A role for the elongator complex in zygotic paternal genome demethylation

21 January 2018

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Properties and localization of DNA methyltransferase in preimplantation mouse embryos: implications for genomic imprinting

21 January 2018

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DNA methyltransferase is actively retained in the cytoplasm during early development

21 January 2018

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The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages

21 January 2018

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Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5.

21 January 2018

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Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning

21 January 2018

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Dynamic transition of Dnmt3b expression in mouse pre- and early post-implantation embryos

21 January 2018

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Embryonic stem cell lines derived from human blastocysts

21 January 2018

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Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes.

21 January 2018

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Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b

21 January 2018

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Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.

21 January 2018

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Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein

21 January 2018

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Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes

21 January 2018

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Sp1 elements protect a CpG island from de novo methylation

21 January 2018

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A unique developmental pattern of Oct-3/4 DNA methylation is controlled by a cis-demodification element

21 January 2018

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Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a.

21 January 2018

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Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites

21 January 2018

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De novo methylation of MMLV provirus in embryonic stem cells: CpG versus non-CpG methylation

21 January 2018

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Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO- T cells

21 January 2018

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Distinct enzymatic properties of recombinant mouse DNA methyltransferases Dnmt3a and Dnmt3b

21 January 2018

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Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density.

21 January 2018

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Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality

21 January 2018

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DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.

21 January 2018

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DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells

21 January 2018

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DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain.

21 January 2018

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DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling.

21 January 2018

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DNMT1 maintains progenitor function in self-renewing somatic tissue

21 January 2018

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Multilineage potential of adult human mesenchymal stem cells

21 January 2018

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Multilineage cells from human adipose tissue: implications for cell-based therapies

21 January 2018

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Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture

21 January 2018

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Stable CpG hypomethylation of adipogenic promoters in freshly isolated, cultured, and differentiated mesenchymal stem cells from adipose tissue

21 January 2018

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Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research.

21 January 2018

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Epigenetic signatures associated with different levels of differentiation potential in human stem cells

21 January 2018

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Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis

21 January 2018

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Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells

21 January 2018

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De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells

21 January 2018

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Stem cell plasticity--building the brain of our dreams

21 January 2018

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Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells

21 January 2018

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Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal

21 January 2018

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Chromatin dynamics during epigenetic reprogramming in the mouse germ line

21 January 2018

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Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

21 January 2018

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Germ line, stem cells, and epigenetic reprogramming

21 January 2018

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DNA methylation profiling of human chromosomes 6, 20 and 22

21 January 2018

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Global, comparative analysis of tissue-specific promoter CpG methylation

21 January 2018

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A novel CpG island set identifies tissue-specific methylation at developmental gene loci

21 January 2018

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An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)

21 January 2018

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Tissue specific differentially methylated regions (TDMR): Changes in DNA methylation during development.

21 January 2018

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Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

21 January 2018

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Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

21 January 2018

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Dissecting direct reprogramming through integrative genomic analysis

21 January 2018

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A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog

21 January 2018

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Active DNA demethylation mediated by DNA glycosylases

21 January 2018

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Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis

21 January 2018

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Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

21 January 2018

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Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

21 January 2018

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GADD45A does not promote DNA demethylation

21 January 2018

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Cyclical DNA methylation of a transcriptionally active promoter

21 January 2018

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Reprogramming towards pluripotency requires AID-dependent DNA demethylation

21 January 2018

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Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures

21 January 2018

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Human embryonic stem cells have a unique epigenetic signature

21 January 2018

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Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome

21 January 2018

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Genomic alterations in cultured human embryonic stem cells

21 January 2018

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Epigenetic status of human embryonic stem cells.

21 January 2018

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Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

21 January 2018

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5-azacytidine induces cardiac differentiation of P19 embryonic stem cells.

21 January 2018

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Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

21 January 2018

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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

21 January 2018

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Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds

21 January 2018

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Brain from bone: efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent

21 January 2018

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Adult bone marrow stromal stem cells express germline, ectodermal, endodermal, and mesodermal genes prior to neurogenesis

21 January 2018

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Unraveling epigenetic regulation in embryonic stem cells

21 January 2018

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A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling

21 January 2018

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Stem cell regulation by polycomb repressors: postponing commitment

21 January 2018

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 January 2018

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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

21 January 2018

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Expanding chemical biology of 2-oxoglutarate oxygenases

21 January 2018

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Demethylation of the zygotic paternal genome

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/RME.10.35

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22 August 2017

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