(Q37775207)

23 August 2017

1 reference

title

GABAB receptor coupling to G-proteins and ion channels (English)

1 reference

23 August 2017

Claire L Padgett

1

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23 August 2017

Paul A Slesinger

series ordinal

2

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23 August 2017

publication date

1 January 2010

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23 August 2017

published in

Advances in Pharmacology

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23 August 2017

volume

58

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23 August 2017

page(s)

123-147

1 reference

A G protein couples serotonin and GABAB receptors to the same channels in hippocampus

23 August 2017

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The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum

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Regulators of G-protein signaling form a quaternary complex with the agonist, receptor, and G-protein. A novel explanation for the acceleration of signaling activation kinetics

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The Sushi domains of GABAB receptors function as axonal targeting signals

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GABA(B) receptor isoforms GBR1a and GBR1b, appear to be associated with pre- and post-synaptic elements respectively in rat and human cerebellum

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GIRK2 deficient mice. Evidence for hyperactivity and reduced anxiety

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Electrophysiology of GABAA and GABAB receptor subtypes

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GABAB receptor pharmacology

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Direct interaction of GABAB receptors with M2 muscarinic receptors enhances muscarinic signaling

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7 January 2021

Presynaptic signaling by heterotrimeric G-proteins

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The expression of GABA(B1) and GABA(B2) receptor subunits in the cNS differs from that in peripheral tissues

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7 January 2021

The C-terminal domains of the GABA(b) receptor subunits mediate intracellular trafficking but are not required for receptor signaling.

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7 January 2021

Voltage-dependent calcium channels in rat midbrain dopamine neurons: modulation by dopamine and GABAB receptors.

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7 January 2021

Structure and regulation of voltage-gated Ca2+ channels

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7 January 2021

Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons

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7 January 2021

Comparative immunohistochemical localisation of GABA(B1a), GABA(B1b) and GABA(B2) subunits in rat brain, spinal cord and dorsal root ganglion

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7 January 2021

Endogenous regulators of G protein signaling proteins regulate presynaptic inhibition at rat hippocampal synapses

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Presynaptic GABAB autoreceptor modulation of P/Q-type calcium channels and GABA release in rat suprachiasmatic nucleus neurons.

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7 January 2021

Hyperpolarization by GABAB receptor agonists in mid-brain periaqueductal gray neurones in vitro

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7 January 2021

Evidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K+ channels

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7 January 2021

Intracellular retention of recombinant GABAB receptors

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7 January 2021

Association of GABA(B) receptors and members of the 14-3-3 family of signaling proteins

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7 January 2021

Marlin-1, a novel RNA-binding protein associates with GABA receptors

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7 January 2021

Cyclic AMP-dependent protein kinase phosphorylation facilitates GABA(B) receptor-effector coupling

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7 January 2021

Bi-directional effects of GABA(B) receptor agonists on the mesolimbic dopamine system

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7 January 2021

Two cytoplasmic loops of the glucagon receptor are required to elevate cAMP or intracellular calcium

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7 January 2021

Signalling via the G protein-activated K+ channels

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7 January 2021

GABAB autoreceptors regulate the induction of LTP

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7 January 2021

Presynaptic and postsynaptic GABAB receptors of neocortical neurons of the rat in vitro: differences in pharmacology and ionic mechanisms.

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7 January 2021

gamma-Aminobutyric acid-induced depression of calcium currents of chick sensory neurons

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7 January 2021

Determination of the minimal functional ligand-binding domain of the GABAB1b receptor.

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7 January 2021

Regulators of G protein signaling proteins as determinants of the rate of desensitization of presynaptic calcium channels

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7 January 2021

G protein modulation of voltage-gated calcium channels

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7 January 2021

Calcium channel involvement in GABAB receptor-mediated inhibition of GABA release in area CA1 of the rat hippocampus.

1 reference

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7 January 2021

A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor

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7 January 2021

Phosphorylation and chronic agonist treatment atypically modulate GABAB receptor cell surface stability

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7 January 2021

Ethanol enhances GABAB-mediated inhibitory postsynaptic transmission on rat midbrain dopaminergic neurons by facilitating GIRK currents

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7 January 2021

Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits

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7 January 2021

Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells.

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7 January 2021

Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins

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7 January 2021

GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal cells in hippocampal cultures

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7 January 2021

Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function

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7 January 2021

Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding

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7 January 2021

Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors

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7 January 2021

Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice.

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7 January 2021

Agonist-induced desensitization and endocytosis of heterodimeric GABAB receptors in CHO-K1 cells

1 reference

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7 January 2021

Inhibition of N- and P/Q-type calcium channels by postsynaptic GABAB receptor activation in rat supraoptic neurones

1 reference

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7 January 2021

The intracellular loops of the GB2 subunit are crucial for G-protein coupling of the heteromeric gamma-aminobutyrate B receptor

1 reference

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7 January 2021

The role of GABAB receptor activation in absence seizures of lethargic (lh/lh) mice

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7 January 2021

The involvement of multiple calcium channel sub-types in glutamate release from cerebellar granule cells and its modulation by GABAB receptor activation

1 reference

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7 January 2021

A comparison of the effect of calcium channel ligands and GABAB agonists and antagonists on transmitter release and somatic calcium channel currents in cultured neurons

1 reference

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7 January 2021

Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra.

1 reference

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7 January 2021

Baclofen activates voltage-dependent and 4-aminopyridine sensitive K+ conductance in guinea-pig hippocampal pyramidal cells maintained in vitro

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7 January 2021

Characterization of pre- and postsynaptic actions of (-)-baclofen in the guinea-pig hippocampus in vitro

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7 January 2021

Presynaptic inhibition by baclofen of miniature EPSCs and IPSCs in substantia gelatinosa neurons of the adult rat spinal dorsal horn

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7 January 2021

Effects of repeated cocaine on medial prefrontal cortical GABAB receptor modulation of neurotransmission in the mesocorticolimbic dopamine system

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7 January 2021

Effects of cocaine-induced behavioural sensitization on GABA transmission within rat medial prefrontal cortex

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7 January 2021

Differential regulation of G protein-gated inwardly rectifying K(+) channel kinetics by distinct domains of RGS8

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7 January 2021

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

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7 January 2021

Heterodimerization of a functional GABAB receptor is mediated by parallel coiled-coil alpha-helices

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7 January 2021

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

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7 January 2021

GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

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7 January 2021

Receptor-mediated hydrolysis of plasma membrane messenger PIP2 leads to K+-current desensitization.

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7 January 2021

Agonist-induced desensitization of the mu opioid receptor-coupled potassium channel (GIRK1).

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7 January 2021

Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells.

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7 January 2021

Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus.

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7 January 2021

Role of heteromer formation in GABAB receptor function

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7 January 2021

RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area.

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7 January 2021

Contribution of Kir3.1, Kir3.2A and Kir3.2C subunits to native G protein‐gated inwardly rectifying potassium currents in cultured hippocampal neurons

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7 January 2021

The role of members of the pertussis toxin-sensitive family of G proteins in coupling receptors to the activation of the G protein-gated inwardly rectifying potassium channel

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7 January 2021

GABAB receptors as drug targets to treat gastroesophageal reflux disease

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7 January 2021

Role of presynaptic muscarinic and GABA(B) receptors in spinal glutamate release and cholinergic analgesia in rats

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7 January 2021

Activation of postsynaptic GABAB receptors modulate the firing activity of supraoptic oxytocin and vasopressin neurones: role of calcium channels

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7 January 2021

Lipid rafts as functional heterogeneity in cell membranes

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7 January 2021

Involvement of intrathalamic GABAB neurotransmission in the control of absence seizures in the rat.

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7 January 2021

Addictive drugs modulate GIRK-channel signaling by regulating RGS proteins

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7 January 2021

A unique sorting nexin regulates trafficking of potassium channels via a PDZ domain interaction

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7 January 2021

The N-terminal domain of gamma-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding.

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7 January 2021

A trafficking checkpoint controls GABA(B) receptor heterodimerization

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7 January 2021

Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors

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7 January 2021

Ligand-induced signal transduction within heterodimeric GABA(B) receptor

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7 January 2021

Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization

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7 January 2021

Transcriptional regulation by the phosphorylation-dependent factor CREB

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7 January 2021

G(o) transduces GABAB-receptor modulation of N-type calcium channels in cultured dorsal root ganglion neurons

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7 January 2021

Dopamine inhibits GABA(A) currents in ventral tegmental area dopamine neurons via activation of presynaptic G-protein coupled inwardly-rectifying potassium channels

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7 January 2021

GABAB receptor inhibition of P-type Ca2+ channels in central neurons

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7 January 2021

A physiological role for GABAB receptors and the effects of baclofen in the mammalian central nervous system

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7 January 2021

GABAB receptors couple to G proteins Go, Go* and Gi1 but not to Gi2.

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7 January 2021

Endogenous RGS proteins enhance acute desensitization of GABA(B) receptor-activated GIRK currents in HEK-293T cells

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7 January 2021

Functional coupling of Gi subtype with GABAB receptor/adenylyl cyclase system: analysis using a reconstituted system with purified GTP-binding protein from bovine cerebral cortex

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7 January 2021

GABAB receptor-mediated regulation of glutamate-activated calcium transients in hypothalamic and cortical neuron development

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7 January 2021

(-)-Baclofen-induced and constitutively active inwardly rectifying potassium conductances in cultured rat midbrain neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Measurement of receptor-mediated functional activation of G proteins in postmortem human brain membranes

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https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

3-Aminopropanephosphinic acid is a potent agonist at peripheral and central presynaptic GABAB receptors

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https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Baclofen increases the potassium conductance of rat locus coeruleus neurons recorded in brain slices

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https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Contribution of Ih and GABAB to synaptically induced afterhyperpolarizations in CA1: a brake on the NMDA response

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https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

The GABAB1b isoform mediates long-lasting inhibition of dendritic Ca2+ spikes in layer 5 somatosensory pyramidal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Phosphorylation-independent desensitization of GABA(B) receptor by GRK4

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Lateral diffusion of the GABAB receptor is regulated by the GABAB2 C terminus.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Potassium channels activated by GABAB agonists and serotonin in cultured hippocampal neurons

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7 January 2021

Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice

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https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Arrestin is required for agonist-induced trafficking of voltage-dependent calcium channels

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https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Effects of GABA agonists on body temperature regulation in GABA(B(1))-/- mice

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7 January 2021

Dendritic assembly of heteromeric gamma-aminobutyric acid type B receptor subunits in hippocampal neurons

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https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

The use of FRET microscopy to elucidate steady state channel conformational rearrangements and G protein interaction with the GIRK channels.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

N-type Ca2+ channels as scaffold proteins in the assembly of signaling molecules for GABAB receptor effects

1 reference

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7 January 2021

Effects of gamma-aminobutyric acid and (-)-baclofen on calcium and potassium currents in cat dorsal root ganglion neurones in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Simultaneous stimulation of GABA and beta adrenergic receptors stabilizes isotypes of activated adenylyl cyclase heterocomplex

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Regulator of G protein signaling 8 (RGS8) requires its NH2 terminus for subcellular localization and acute desensitization of G protein-gated K+ channels

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Regulation of intracellular [Ca2+] and GABA release by presynaptic GABAB receptors in rat cerebrocortical synaptosomes

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7 January 2021

GABA spillover activates postsynaptic GABA(B) receptors to control rhythmic hippocampal activity

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https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Evidence of involvement of GIRK1/GIRK4 in long-term desensitization of cardiac muscarinic K+ channels

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2

1 reference

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7 January 2021

Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice

1 reference

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7 January 2021

Baclofen inhibits guinea pig magnocellular neurones via activation of an inwardly rectifying K+ conductance

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Receptor-specific inhibition of GABAB-activated K+ currents by muscarinic and metabotropic glutamate receptors in immature rat hippocampus

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7 January 2021

Rapid and long-term alterations of hippocampal GABAB receptors in a mouse model of temporal lobe epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Ca2+ activity at GABAB receptors constitutively promotes metabotropic glutamate signaling in the absence of GABA.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

G-Protein-coupled modulation of presynaptic calcium currents and transmitter release by a GABAB receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Baclofen inhibits high-threshold calcium currents with two distinct modes in rat hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Acute desensitization of presynaptic GABAB-mediated inhibition and induction of epileptiform discharges in the neonatal rat hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

RGS3 mediates a calcium-dependent termination of G protein signaling in sensory neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Dominant role of GABAB2 and Gbetagamma for GABAB receptor-mediated-ERK1/2/CREB pathway in cerebellar neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Pharmacology, distribution, cellular localization, and development of GABAB binding in rodent cerebellum

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Differential compartmentalization and distinct functions of GABAB receptor variants

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Baclofen inhibition of the hyperpolarization-activated cation current, Ih, in rat substantia nigra zona compacta neurons may be secondary to potassium current activation.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Heterodimerization is required for the formation of a functional GABA(B) receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2958006-2

7 January 2021

10.1016/S1054-3589(10)58006-2

Identifiers

DOI

1 reference

23 August 2017

1 reference