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Intracellular and extracellular tau.
scientific article published on 28 June 2010
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2907258
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23 August 2017
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title
Intracellular and extracellular tau.
(English)
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PMCID
2907258
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23 August 2017
author name string
Jesús Avila
series ordinal
1
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PMCID
2907258
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23 August 2017
publication date
28 June 2010
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PMCID
2907258
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23 August 2017
published in
Frontiers in Neuroscience
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2907258
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23 August 2017
volume
4
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PMCID
2907258
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23 August 2017
page(s)
49
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2907258
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23 August 2017
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Tau deficiency leads to the upregulation of BAF-57, a protein involved in neuron-specific gene repression
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Prefilament tau species as potential targets for immunotherapy for Alzheimer disease and related disorders
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Hyperphosphorylated tau is a cause of neuronal dysfunction in tauopathy.
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Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice
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Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
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Differential regulation of dynein and kinesin motor proteins by tau
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Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau
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Tau phosphorylation sites work in concert to promote neurotoxicity in vivo
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Tauopathies
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Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model
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23 August 2017
Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity
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Tau suppression in a neurodegenerative mouse model improves memory function
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The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates beta-amyloid-induced neurodegeneration.
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Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
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23 August 2017
Role of tau protein in both physiological and pathological conditions.
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23 August 2017
Modeling tau polymerization in vitro: a review and synthesis
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23 August 2017
Tau is essential to beta -amyloid-induced neurotoxicity
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23 August 2017
Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau
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23 August 2017
Altered microtubule organization in small-calibre axons of mice lacking tau protein
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Amyloid plaque core protein in Alzheimer disease and Down syndrome
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23 August 2017
Tau protein function in living cells
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23 August 2017
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
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23 August 2017
Neuropathological stageing of Alzheimer-related changes
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A protein factor essential for microtubule assembly
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Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin
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Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons
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23 August 2017
Interneuronal transfer of human tau between Lamprey central neurons in situ
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14 September 2017
Propagation of tau misfolding from the outside to the inside of a cell.
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14 September 2017
Extracellular tau is toxic to neuronal cells.
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14 September 2017
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
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23 June 2018
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.
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23 June 2018
Neurofibrillary degeneration and neuronal loss in Alzheimer's disease
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23 June 2018
Role of tau protein on neocortical and hippocampal oscillatory patterns.
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1 September 2018
GSK3β overexpression induces neuronal death and a depletion of the neurogenic niches in the dentate gyrus.
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1 September 2018
Tau protein role in sleep-wake cycle.
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1 September 2018
Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein.
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1 September 2018
Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits.
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1 September 2018
Tau--an inhibitor of deacetylase HDAC6 function.
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1 September 2018
Characteristics and consequences of muscarinic receptor activation by tau protein.
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1 September 2018
Human misfolded truncated tau protein promotes activation of microglia and leukocyte infiltration in the transgenic rat model of tauopathy.
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1 September 2018
Subgroups of Alzheimer's disease based on cerebrospinal fluid molecular markers.
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1 September 2018
Site-specific nitration differentially influences tau assembly in vitro
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1 September 2018
Untangling memory deficits.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907258
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1 September 2018
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.
1 reference
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1 September 2018
Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907258
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1 September 2018
Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice.
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PubMed Central
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1 September 2018
Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907258
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1 September 2018
The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907258
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1 September 2018
Neurons may live for decades with neurofibrillary tangles.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907258
retrieved
1 September 2018
Kinetic stabilization of microtubule dynamics at steady state by tau and microtubule-binding domains of tau.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907258
retrieved
1 September 2018
Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907258
retrieved
1 September 2018
Identifiers
DOI
10.3389/FNINS.2010.00049
1 reference
stated in
Europe PubMed Central
PMCID
2907258
retrieved
23 August 2017
PMCID
2907258
1 reference
stated in
Europe PubMed Central
PMCID
2907258
retrieved
23 August 2017
PubMed ID
20661459
1 reference
stated in
Europe PubMed Central
PMCID
2907258
retrieved
23 August 2017
ResearchGate publication ID
45367064
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