(Q37782962)

23 August 2017

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title

The role of pharmacological profiling in safety assessment (English)

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23 August 2017

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Williams PD

1

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23 August 2017

language of work or name

English

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publication date

1 December 1990

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Regulatory Toxicology and Pharmacology

23 August 2017

published in

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23 August 2017

volume

12

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23 August 2017

issue

3 Pt 1

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23 August 2017

page(s)

238-252

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Arrhythmias and inhibition of noradrenaline uptake caused by tricyclic antidepressants and chlorpromazine on the isolated perfused rabbit heart

23 August 2017

cites work

1 reference

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7 January 2021

The effects of the tricyclic antidepressants desipramine, doxepin and iprindole on the isolated perfused rabbit heart.

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7 January 2021

Synthesis and biological evaluation of a series of parenteral 3'-quaternary ammonium cephalosporins

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7 January 2021

Correlation between plasma diphenhydramine level and sedative and antihistamine effects

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7 January 2021

2% topical minoxidil solution in male-pattern baldness: preliminary European results

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7 January 2021

Topical minoxidil for androgenetic alopecia: optimizing the chance for success by appropriate patient selection

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7 January 2021

Antihypertensive effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) in conscious dogs

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7 January 2021

Cardiovascular effects of amitriptyline, nortriptyline, protriptyline and doxepin in conscious rabbits

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7 January 2021

Bromocriptine and uterine neoplasia

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7 January 2021

8-OH-DPAT, flesinoxan and guanfacine: systemic and regional haemodynamic effects of centrally acting antihypertensive agents in anaesthetized rabbits

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7 January 2021

Nonclinical toxicity studies of antiviral drugs indicated for the treatment of non-life-threatening diseases: evaluation of drug toxicity prior to phase 1 clinical studies

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7 January 2021

Beta-adrenoceptor stimulants and mesovarian leiomyomas in the rat

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7 January 2021

Preclinical evaluation of lovastatin

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7 January 2021

Selective interaction of novel anxiolytics with 5-hydroxytryptamine1A receptors.

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7 January 2021

Brain 5-HT1A receptor agonism: a novel mechanism for antihypertensive action.

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7 January 2021

Antibiotic-induced Paralysis of the Mouse Phrenic Nerve–Hemidiaphragm Preparation, and Reversibility by Calcium and by Neostigmine

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7 January 2021

Observations on the thyroid gland in rats following the administration of sulfamethoxazole and trimethoprim

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7 January 2021

Induction and reversibility of thyroid proliferative changes in rats given an antithyroid compound

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7 January 2021

Animal model for evaluating the convulsive liability of beta-lactam antibiotics

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7 January 2021

The significance of pharmacologic screening tests in the preclinical safety evaluation of new drugs

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7 January 2021

10.1016/S0273-2300(05)80061-3

Identifiers

DOI

1 reference

23 August 2017

1 reference