(Q37783191)

23 August 2017

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title

Structure-activity relationships (SAR) and structure-metabolism relationships (SMR) affecting the teratogenicity of carboxylic acids (English)

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23 August 2017

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Di Carlo FJ

1

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23 August 2017

language of work or name

English

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publication date

1 January 1990

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23 August 2017

published in

Drug Metabolism Reviews

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23 August 2017

volume

22

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23 August 2017

issue

5

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23 August 2017

page(s)

411-449

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Structure-metabolism relationships (SMR) for the prediction of health hazards by the Environmental Protection Agency. II. Application to teratogenicity and other toxic effects caused by aliphatic acids

23 August 2017

cites work

1 reference

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An in vitro assay for teratogens with cultures of rat embryo midbrain and limb bud cells

21 January 2018

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Mechanisms of Teratogenesis

21 January 2018

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Proposed mechanisms of action in thalidomide embryopathy

21 January 2018

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Chemical teratogenesis: testing methods and the role of metabolism

21 January 2018

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Ethylene glycol monomethyl ether (EGME) inhibits rat embryo ornithine decarboxylase (ODC) activity

21 January 2018

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Metabolism and disposition of glycol ethers

21 January 2018

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Teratogenicity of dimethoxyethyl phthalate and its metabolites methoxyethanol and methoxyacetic acid in the rat.

21 January 2018

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The possible role of one-carbon moieties in 2-methoxyethanol and 2-methoxyacetic acid-induced developmental toxicity

21 January 2018

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Enzymatic properties of dimethylglycine dehydrogenase and sarcosine dehydrogenase from rat liver

21 January 2018

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Asymmetric synthesis and enantioselective teratogenicity of 2-n-propyl-4-pentenoic acid (4-en-VPA), an active metabolite of the anticonvulsant drug, valproic acid

21 January 2018

1 reference

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Asymmetric synthesis and teratogenic activity of (R)- and (S)-2-ethylhexanoic acid, a metabolite of the plasticizer di-(2-ethylhexyl)phthalate

21 January 2018

1 reference

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Teratogenicity and placental transfer of all-trans-, 13-cis-, 4-oxo-all-trans-, and 4-oxo-13-cis-retinoic acid after administration of a low oral dose during organogenesis in mice

21 January 2018

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Terpenoid biotransformation in mammals. V. Metabolism of (+)-citronellal, (+-)-7-hydroxycitronellal, citral, (-)-perillaldehyde, (-)-myrtenal, cuminaldehyde, thujone, and (+-)-carvone in rabbits

21 January 2018

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Identification and quantification of octanoyl glucuronide in the urine of children who ingested medium-chain triglycerides

21 January 2018

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A human retinoic acid receptor which belongs to the family of nuclear receptors

21 January 2018

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Identification of a receptor for the morphogen retinoic acid

21 January 2018

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The steroid and thyroid hormone receptor superfamily

21 January 2018

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Ornithine decarboxylase: a key regulatory enzyme in normal and neoplastic growth

21 January 2018

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Pharmacologic evaluation of various metabolites and analogs of valproic acid: teratogenic potencies in mice

21 January 2018

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The teratogenic potential of alkoxy acids in post-implantation rat embryo culture: structure-activity relationships.

21 January 2018

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Pharmacokinetic aspects of drug effects in vitro (II) placental transfer to the embryo and activity of some carboxylic acids structurally related to valproic acid in whole embryos in culture

21 January 2018

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Spina bifida and in-utero exposure to valproate

21 January 2018

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Valproate and spina bifida

21 January 2018

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Teratogenicity of di(2-ethylhexyl) phthalate, 2-ethylhexanol, 2-ethylhexanoic acid, and valproic acid, and potentiation by caffeine

21 January 2018

1 reference

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[Structural bases of the teratogenic effects of the antiepileptic valproic acid. 2-n-propyl-4-pentenic acid, the first structural analogue with significantly higher teratogenic action than VPA].

21 January 2018

1 reference

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Structure-activity relationships of retinoids in developmental toxicology. III. Contribution of the vitamin A beta-cyclogeranylidene ring

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991446

Structure-activity relationships of retinoids in developmental toxicology. II. Influence of the polyene chain of the vitamin A molecule

21 January 2018

1 reference

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Structure-activity relationships of retinoids in developmental toxicology. I. Studies on the nature of the polar terminus of the vitamin A molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991446

10.3109/03602539008991446

21 January 2018

Identifiers

DOI

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Fatcat ID

release_4xkssbhi7rhjbb6uhaj7pr3zxe

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4xkssbhi7rhjbb6uhaj7pr3zxe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference