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Lgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathway
scientific article published on 21 October 2010
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scholarly article
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Europe PubMed Central
PMC publication ID
3174480
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798605%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
title
Lgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathway
(English)
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Europe PubMed Central
PMC publication ID
3174480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798605%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
author
Helena E. Richardson
series ordinal
4
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Europe PubMed Central
PMC publication ID
3174480
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798605%20AND%20SRC:MED&resulttype=core&format=json
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12 February 2020
Linda M. Parsons
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1
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Europe PubMed Central
PMC publication ID
3174480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798605%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
author name string
Nicola A Grzeschik
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2
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PMC publication ID
3174480
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798605%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
Melinda L Allott
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3
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3174480
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798605%20AND%20SRC:MED&resulttype=core&format=json
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12 February 2020
language of work or name
English
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publication date
21 October 2010
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Europe PubMed Central
PMC publication ID
3174480
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798605%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
published in
Fly
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Europe PubMed Central
PMC publication ID
3174480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798605%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
volume
4
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12 February 2020
issue
4
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3174480
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retrieved
12 February 2020
page(s)
288-293
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3174480
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retrieved
12 February 2020
cites work
Upstream regulation of the hippo size control pathway
1 reference
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PubMed Central
reference URL
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The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
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Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded
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Crumbs is required to achieve proper organ size control during Drosophila head development
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The Hippo pathway regulates apical-domain size independently of its growth-control function
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DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.
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Crumbs interacts with moesin and beta(Heavy)-spectrin in the apical membrane skeleton of Drosophila
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Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres
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The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
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6 September 2017
The FERM protein Yurt is a negative regulatory component of the Crumbs complex that controls epithelial polarity and apical membrane size.
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6 September 2017
The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie
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The Drosophila RASSF homolog antagonizes the hippo pathway
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Self-refinement of Notch activity through the transmembrane protein Crumbs: modulation of gamma-secretase activity
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Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis
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23 June 2018
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms.
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PubMed Central
reference URL
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1 September 2018
Cdc42, Par6, and aPKC regulate Arp2/3-mediated endocytosis to control local adherens junction stability.
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1 September 2018
Drosophila Cip4 and WASp define a branch of the Cdc42-Par6-aPKC pathway regulating E-cadherin endocytosis.
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1 September 2018
Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila.
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reference URL
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1 September 2018
Identifiers
DOI
10.4161/FLY.4.4.13116
1 reference
stated in
Europe PubMed Central
PMC publication ID
3174480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798605%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
PMC publication ID
3174480
1 reference
stated in
Europe PubMed Central
PMC publication ID
3174480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798605%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
PubMed publication ID
20798605
1 reference
stated in
Europe PubMed Central
PMC publication ID
3174480
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798605%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 February 2020
ResearchGate publication ID
46009828
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