(Q37790266)

23 August 2017

title

Genetic causes and treatment of isolated growth hormone deficiency-an update (English)

1 reference

23 August 2017

Kyriaki S Alatzoglou

1

1 reference

23 August 2017

Mehul T Dattani

series ordinal

2

1 reference

23 August 2017

publication date

1 October 2010

1 reference

Nature Reviews Endocrinology

23 August 2017

published in

1 reference

23 August 2017

volume

6

1 reference

23 August 2017

issue

10

1 reference

23 August 2017

page(s)

562-576

1 reference

https://scigraph.springernature.com/pub.10.1038/nrendo.2010.147

23 August 2017

exact match

0 references

cites work

Unusual phenotypic features in a patient with a novel splice mutation in the GHRHR gene

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A new mutation in the growth hormone-releasing hormone receptor gene in two Israeli Arab families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Current status of biosimilar growth hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Genetic control of growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Expanding the spectrum of mutations in GH1 and GHRHR: genetic screening in a large cohort of patients with congenital isolated growth hormone deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Heterozygous HESX1 mutations associated with isolated congenital pituitary hypoplasia and septo-optic dysplasia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Transcription factor SOX3 is involved in X-linked mental retardation with growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

The molecular genetics of growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Human growth hormone 1 (GH1) gene expression: complex haplotype-dependent influence of polymorphic variation in the proximal promoter and locus control region.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Specification of unique Pit-1 activity in the hGH locus control region

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Alternative splicing and evolution: diversification, exon definition and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

GH1 splicing is regulated by multiple enhancers whose mutation produces a dominant-negative GH isoform that can be degraded by allele-specific small interfering RNA (siRNA).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Defects in growth hormone receptor signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A Chinese familial growth hormone deficiency with a deletion of 7.1 kb of DNA

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Detection of molecular heterogeneity in GH-1 gene deletions by analysis of polymerase chain reaction amplification products

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Familial growth hormone deficiency resulting from a 7.6 kb deletion within the growth hormone gene cluster

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Isolated growth hormone deficiency type IA associated with a 45-kilobase gene deletion within the human growth hormone gene cluster in an Italian family

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Isolated growth hormone (GH) deficiency type 1A associated with a double deletion in the human GH gene cluster

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A new mutation causing inherited growth hormone deficiency: a compound heterozygote of a 6.7 kb deletion and a two base deletion in the third exon of the GH-1 gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Complex disease phenotype revealed by GH deficiency associated with a novel and unusual defect in the GH-1 gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Short stature in carriers of recessive mutation causing familial isolated growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Molecular basis for familial isolated growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Genetic screening of a Dutch population with isolated GH deficiency (IGHD).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A novel IVS2 -2A>T splicing mutation in the GH-1 gene in familial isolated growth hormone deficiency type II in the spectrum of other splicing mutations in the Russian population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A novel mutation at the donor splice site of intron 3 of the GH-I gene in a patient with isolated growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A novel and de novo splice-donor site mutation in intron 3 of the GH-1 gene in a patient with isolated growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A novel splicing mutation in exon 4 (456G>A) of the GH1 gene in a patient with congenital isolated growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Autosomal dominant growth hormone deficiency disrupts secretory vesicles in vitro and in vivo in transgenic mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Isolated autosomal dominant growth hormone deficiency: stimulating mutant GH-1 gene expression drives GH-1 splice-site selection, cell proliferation, and apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

An exon splice enhancer mutation causes autosomal dominant GH deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

An exonic mutation of the GH-1 gene causing familial isolated growth hormone deficiency type II

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Isolated growth hormone deficiency type II caused by a point mutation that alters both splice site strength and splicing enhancer function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Exon splice enhancer mutation (GH-E32A) causes autosomal dominant growth hormone deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Novel mutations of the growth hormone 1 (GH1) gene disclosed by modulation of the clinical selection criteria for individuals with short stature

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A novel mechanism of aberrant pre-mRNA splicing in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Characterization of an intron splice enhancer that regulates alternative splicing of human GH pre-mRNA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A novel deletion in the GH1 gene including the IVS3 branch site responsible for autosomal dominant isolated growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Brief report: short stature caused by a mutant growth hormone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Detection of growth hormone gene defects by dideoxy fingerprinting (ddF)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Biologically inactive growth hormone caused by an amino acid substitution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A novel dysfunctional growth hormone variant (Ile179Met) exhibits a decreased ability to activate the extracellular signal-regulated kinase pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

GH mutant (R77C) in a pedigree presenting with the delay of growth and pubertal development: structural analysis of the mutant and evaluation of the biological activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Prolonged retention after aggregation into secretory granules of human R183H-growth hormone (GH), a mutant that causes autosomal dominant GH deficiency type II.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Variability of isolated autosomal dominant GH deficiency (IGHD II): impact of the P89L GH mutation on clinical follow-up and GH secretion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Growth hormone (GH) deficiency type II: a novel GH-1 gene mutation (GH-R178H) affecting secretion and action

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Isolated GH deficiency (IGHD) type II: imaging of the pituitary gland by magnetic resonance reveals characteristic differences in comparison with severe IGHD of unknown origin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Variable phenotypes in familial isolated growth hormone deficiency caused by a G6664A mutation in the GH-1 gene.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A molecular basis for variation in clinical severity of isolated growth hormone deficiency type II.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Isolated autosomal dominant growth hormone deficiency: an evolving pituitary deficit? A multicenter follow-up study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Evolution of gonadotropin deficiency in a patient with type II autosomal dominant GH deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Growth hormone (GH)-releasing hormone increases the expression of the dominant-negative GH isoform in cases of isolated GH deficiency due to GH splice-site mutations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

GHRH proliferative action on somatotrophs is cell-type specific and dependent on Pit-1/GHF-1 expression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Nonsense mutation in the human growth hormone-releasing hormone receptor causes growth failure analogous to the little (lit) mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Isolated growth hormone (GH) deficiency due to compound heterozygosity for two new mutations in the GH-releasing hormone receptor gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Serum GH response to pharmacological stimuli and physical exercise in two siblings with two new inactivating mutations in the GH-releasing hormone receptor gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Growth hormone (GH) secretion in patients with an inactivating defect of the GH-releasing hormone (GHRH) receptor is pulsatile: evidence for a role for non-GHRH inputs into the generation of GH pulses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Identification of a novel splicing mutation in the growth hormone (GH)-releasing hormone receptor gene in a Chinese family with pituitary dwarfism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A recurrent signal peptide mutation in the growth hormone releasing hormone receptor with defective translocation to the cell surface and isolated growth hormone deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A new missense mutation in the growth hormone-releasing hormone receptor gene in familial isolated GH deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Variability in anterior pituitary size within members of a family with GH deficiency due to a new splice mutation in the GHRH receptor gene.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Naturally-occurring missense mutations in the human growth hormone-releasing hormone receptor alter ligand binding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Detection of a recurring mutation in the human growth hormone-releasing hormone receptor gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Heterozygosity for a mutation in the growth hormone-releasing hormone receptor gene does not influence adult stature, but affects body composition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

X-linked hypogammaglobulinemia and isolated growth hormone deficiency: an update

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

SOX3 is required during the formation of the hypothalamo-pituitary axis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Array comparative genomic hybridisation analysis of boys with X linked hypopituitarism identifies a 3.9 Mb duplicated critical region at Xq27 containing SOX3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Over- and underdosage of SOX3 is associated with infundibular hypoplasia and hypopituitarism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Ghrelin: structure and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Endogenous ghrelin regulates episodic growth hormone (GH) secretion by amplifying GH Pulse amplitude: evidence from antagonism of the GH secretagogue-R1a receptor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Recessive isolated growth hormone deficiency and mutations in the ghrelin receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Deletion of Ghrelin Impairs neither Growth nor Appetite

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Mutation analysis of the muscarinic cholinergic receptor genes in isolated growth hormone deficiency type IB.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

HESX1 mutations are an uncommon cause of septooptic dysplasia and hypopituitarism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Novel mutations within the POU1F1 gene associated with variable combined pituitary hormone deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Is growth hormone stimulation testing in children still appropriate?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Results of early reevaluation of growth hormone secretion in short children with apparent growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Pituitary magnetic resonance imaging and function in patients with growth hormone deficiency with and without mutations in GHRH-R, GH-1, or PROP-1 genes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Deterioration of growth hormone (GH) response and anterior pituitary function in young adults with childhood-onset GH deficiency and ectopic posterior pituitary: a two-year prospective follow-up study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Do all patients with childhood-onset growth hormone deficiency (GHD) and ectopic neurohypophysis have persistent GHD in adulthood?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Subnormal serum insulin-like growth factor-I levels in young adults with childhood-onset nonacquired growth hormone (GH) deficiency who recover normal gh secretion may indicate less severe but persistent pituitary failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Treatment of a pituitary dwarf with human growth hormone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Long-term safety of recombinant human growth hormone in children

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Use of growth hormone in children

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Effects of dose and gender on the growth and growth factor response to GH in GH-deficient children: implications for efficacy and safety

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A randomised study of two doses of biosynthetic human growth hormone on final height of pubertal children with growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Treatment of GH-deficient children with two different GH doses: effect on final height and cost-benefit implications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Adult height after long term treatment with recombinant growth hormone for idiopathic isolated growth hormone deficiency: observational follow up study of the French population based registry

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Effect of growth hormone (GH) treatment on the near-final height of 1258 patients with idiopathic GH deficiency: analysis of a large international database

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Growth hormone (GH) provocation tests and the response to GH treatment in GH deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

The mathematical model for total pubertal growth in idiopathic growth hormone (GH) deficiency suggests a moderate role of GH dose

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Validated multivariate models predicting the growth response to GH treatment in individual short children with a broad range in GH secretion capacities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Prediction of adult height in growth-hormone-treated children with growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Insulin growth factor-based dosing of growth hormone therapy in children: a randomized, controlled study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Growth hormone (GH) dosing during catch-up growth guided by individual responsiveness decreases growth response variability in prepubertal children with GH deficiency or idiopathic short stature

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Observed and predicted growth responses in prepubertal children with growth disorders: guidance of growth hormone treatment by empirical variables.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Height velocity targets from the national cooperative growth study for first-year growth hormone responses in short children

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Pharmacogenomics and pharmacoproteomics in the evaluation and management of short stature

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A common polymorphism of the growth hormone receptor is associated with increased responsiveness to growth hormone.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

The growth response to growth hormone (GH) treatment in children with isolated GH deficiency is independent of the presence of the exon 3-minus isoform of the GH receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Species-specific alternative splice mimicry at the growth hormone receptor locus revealed by the lineage of retroelements during primate evolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Growth hormone (GH1) gene variation and the growth hormone receptor (GHR) exon 3 deletion polymorphism in a West-African population.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Common polymorphisms of the growth hormone (GH) receptor do not correlate with the growth response to exogenous recombinant human GH in GH-deficient children

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Growth hormone (GH) pharmacogenetics: influence of GH receptor exon 3 retention or deletion on first-year growth response and final height in patients with severe GH deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

The exon 3-deleted/full-length growth hormone receptor polymorphism did not influence growth response to growth hormone therapy over two years in prepubertal short children born at term with adequate weight and length for gestational age.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Influence of the d3-growth hormone (GH) receptor isoform on short-term and long-term treatment response to GH replacement in GH-deficient adults

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Impact of the exon 3-deleted growth hormone (GH) receptor polymorphism on baseline height and the growth response to recombinant human GH therapy in GH-deficient (GHD) and non-GHD children with short stature: a systematic review and meta-analysis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Growth Hormone (GH) receptor C.1319 G>T polymorphism, but not exon 3 retention or deletion is associated with better first-year growth response to GH therapy in patients with GH deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Comparison between weight-based and IGF-I-based growth hormone (GH) dosing in the treatment of children with GH deficiency and influence of exon 3 deleted GH receptor variant.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

GH receptor d3 polymorphism in Dutch patients with MPHD and IGHD born small or appropriate for gestational age

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Influence of growth hormone (GH) receptor deletion of exon 3 and full-length isoforms on GH response and final height in patients with severe GH deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

The -202 A allele of insulin-like growth factor binding protein-3 (IGFBP3) promoter polymorphism is associated with higher IGFBP-3 serum levels and better growth response to growth hormone treatment in patients with severe growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Monitoring of concordance in growth hormone therapy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A long-acting, mono-PEGylated human growth hormone analog is a potent stimulator of weight gain and bone growth in hypophysectomized rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A multicenter study of the efficacy and safety of sustained release GH in the treatment of naive pediatric patients with GH deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (nutropin depot) in GH-deficient children

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

The pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (nutropin depot) in GH-deficient adults

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Efficacy of a long-acting growth hormone (GH) preparation in patients with adult GH deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Comparative pharmacokinetics and pharmacodynamics of a new sustained-release growth hormone (GH), LB03002, versus daily GH in adults with GH deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Lipoatrophy in GH deficient patients treated with a long-acting pegylated GH

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Pharmacokinetic and pharmacodynamic profile of a new sustained-release GH formulation, LB03002, in children with GH deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Rescue of pituitary function in a mouse model of isolated growth hormone deficiency type II by RNA interference

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

Short Stature Caused by a Biologically Inactive Mutant Growth Hormone (GH-C53S)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2010.147

A recurring dominant negative mutation causes autosomal dominant growth hormone deficiency--a clinical research center study

31 March 2020

1 reference

12 December 2020

Three new mutations in the gene for the growth hormone (gh)-releasing hormone receptor in familial isolated gh deficiency type ib.

1 reference

12 December 2020

Final height in children with idiopathic growth hormone deficiency treated with recombinant human growth hormone: the Belgian experience

1 reference

12 December 2020

Consensus guidelines for the diagnosis and treatment of growth hormone (GH) deficiency in childhood and adolescence: summary statement of the GH Research Society. GH Research Society

1 reference

12 December 2020

Prevalence of human GH-1 gene alterations in patients with isolated growth hormone deficiency

1 reference

12 December 2020

Familial dwarfism due to a novel mutation of the growth hormone-releasing hormone receptor gene

1 reference

12 December 2020

Autosomal dominant growth hormone (GH) deficiency type II: the Del32-71-GH deletion mutant suppresses secretion of wild-type GH.

1 reference

12 December 2020

Disruption of exon definition produces a dominant-negative growth hormone isoform that causes somatotroph death and IGHD II

1 reference

12 December 2020

Phenotype and genetic analysis of a syndrome caused by an inactivating mutation in the growth hormone-releasing hormone receptor: Dwarfism of Sindh

1 reference

12 December 2020

Autosomal dominant GH deficiency due to an Arg183His GH-1 gene mutation: clinical and molecular evidence of impaired regulated GH secretion

1 reference

12 December 2020

Genetic basis of endocrine disease. 6. Molecular basis of familial human growth hormone deficiency

1 reference

12 December 2020

Isolated GH deficiency with dominant inheritance: new mutations, new insights

1 reference

12 December 2020

Growth hormone-releasing peptide-2 stimulates GH secretion in GH-deficient patients with mutated GH-releasing hormone receptor

1 reference

12 December 2020

Decreased expression of the GHRH receptor gene due to a mutation in a Pit-1 binding site.

1 reference

12 December 2020

Derivation and validation of a mathematical model for predicting the response to exogenous recombinant human growth hormone (GH) in prepubertal children with idiopathic GH deficiency. KIGS International Board. Kabi Pharmacia International Growth Stu

1 reference

12 December 2020

Heterogeneous growth hormone (GH) gene mutations in familial GH deficiency

1 reference

12 December 2020

Long-acting forms of growth hormone-releasing hormone and growth hormone: effects in normal volunteers and adults with growth hormone deficiency

1 reference

12 December 2020

Inhibition of growth hormone (GH) secretion by a mutant GH-I gene product in neuroendocrine cells containing secretory granules: an implication for isolated GH deficiency inherited in an autosomal dominant manner

1 reference

12 December 2020

Phenotypic variability in familial combined pituitary hormone deficiency caused by a PROP1 gene mutation resulting in the substitution of Arg-->Cys at codon 120 (R120C)

1 reference

12 December 2020

Human growth hormone gene deletion without antibody formation or growth arrest during treatment--a new disease entity?

1 reference

12 December 2020

[Isolated GH deficiency due to inactivating mutation of GHRH receptor]

1 reference

12 December 2020

Impact of del32-71-GH (exon 3 skipped GH) on intracellular GH distribution, secretion and cell viability: a quantitative confocal microscopy analysis

1 reference

12 December 2020

Familial growth hormone deficiency: a model of dominant and recessive mutations affecting a monomeric protein

1 reference

12 December 2020

Screening for growth hormone (GH) gene splice-site mutations in sporadic cases with severe isolated GH deficiency using ectopic transcript analysis

1 reference

12 December 2020

1 reference

12 December 2020

Molecular and cellular basis of isolated dominant-negative growth hormone deficiency, IGHD type II: insights on the secretory pathway of peptide hormones.

1 reference

12 December 2020

New preparations comprising recombinant human growth hormone: deliberations on the issue of biosimilars

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRENDO.2010.147

1 reference

23 August 2017

1 reference