(Q37798963)

23 August 2017

title

I(f) inhibition in cardiovascular diseases (English)

1 reference

23 August 2017

main subject

cardiovascular disease

1 reference

Catherine Thollon

1

1 reference

23 August 2017

Jean-Paul Vilaine

series ordinal

2

1 reference

23 August 2017

publication date

1 January 2010

1 reference

23 August 2017

published in

Advances in Pharmacology

1 reference

23 August 2017

volume

59

1 reference

23 August 2017

page(s)

53-92

1 reference

Properties and modulation of If in newborn versus adult cardiac SA node

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

The anatomy of the cardiac conduction system

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Resting heart rate: a modifiable prognostic indicator of cardiovascular risk and outcomes?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Localization of f-channels to caveolae mediates specific beta2-adrenergic receptor modulation of rate in sinoatrial myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

The cardiac pacemaker current

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Physiology and pharmacology of the cardiac pacemaker ("funny") current

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Heart rate reduction with ivabradine improves erectile dysfunction in parallel to decrease in atherosclerotic plaque load in ApoE-knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Hyperpolarization-activated cation channels: from genes to function

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Mode of action of bradycardic agent, S 16257, on ionic currents of rabbit sinoatrial node cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Molecular regulation and pharmacology of pacemaker channels

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Antianginal and antiischemic effects of ivabradine, an I(f) inhibitor, in stable angina: a randomized, double-blind, multicentered, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Inhibitory actions of ZENECA ZD7288 on whole-cell hyperpolarization activated inward current (If) in guinea-pig dissociated sinoatrial node cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

The sinoatrial node, a heterogeneous pacemaker structure

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Effects of Zeneca ZD7288 in comparison with alinidine and UL-FS 49 on guinea pig sinoatrial node and ventricular action potentials

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

How does adrenaline accelerate the heart?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Current-dependent block of rabbit sino-atrial node I(f) channels by ivabradine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Electrophysiological Effects of a Single Intravenous Administration of Ivabradine (S 16257) in Adult Patients with Normal Baseline Electrophysiology

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Cellular mechanisms underlying the pharmacological induction of phosphenes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Contributions of heart rate and contractility to myocardial oxygen balance during exercise

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Effect of Graded Heart Rate Reduction with Ivabradine on Myocardial Oxygen Consumption and Diastolic Time in Exercising Dogs

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

High heart rate: a cardiovascular risk factor?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Chronic heart rate reduction with ivabradine improves systolic function of the reperfused heart through a dual mechanism involving a direct mechanical effect and a long-term increase in FKBP12/12.6 expression.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Heart rate reduction by ivabradine reduces oxidative stress, improves endothelial function, and prevents atherosclerosis in apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Preservation of coronary reserve by ivabradine-induced reduction in heart rate in infarcted rats is associated with decrease in perivascular collagen

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Selective Hcn1 channels inhibition by ivabradine in mouse rod photoreceptors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Long-term prognostic value of resting heart rate in patients with suspected or proven coronary artery disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Pacemaker mechanisms in cardiac tissue.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Cardiac pacemaker I(f) current and its inhibition by heart rate-reducing agents

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

The role of the funny current in pacemaker activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Computer three-dimensional reconstruction of the sinoatrial node.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Chronic heart rate reduction by ivabradine prevents endothelial dysfunction in dyslipidaemic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

I(f) channel inhibitor ivabradine lowers heart rate in mice with enhanced sympathoadrenergic activities

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

I K1 and I f in ventricular myocytes isolated from control and hypertrophied rat hearts

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Analysis of randomized controlled trials on the effect of magnitude of heart rate reduction on clinical outcomes in patients with systolic chronic heart failure receiving beta-blockers

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Long-term prognostic importance of resting heart rate in patients with left ventricular dysfunction in connection with either heart failure or myocardial infarction: the DIAMOND study

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Resting heart rate in cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Heart rate as a prognostic risk factor in patients with coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a subgroup analysis of a randomised controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Elevated heart rate and atherosclerosis: an overview of the pathogenetic mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Influence of heart rate on mortality among persons with hypertension: the Framingham Study

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Use-dependent block of the pacemaker current I(f) in rabbit sinoatrial node cells by zatebradine (UL-FS 49). On the mode of action of sinus node inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Heart rate in the pathophysiology of coronary blood flow and myocardial ischaemia: benefit from selective bradycardic agents

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Improvement of regional myocardial blood flow and function and reduction of infarct size with ivabradine: protection beyond heart rate reduction

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Usefulness of heart rate at rest as a predictor of mortality, hospitalization for heart failure, myocardial infarction, and stroke in patients with stable coronary heart disease (Data from the Treating to New Targets [TNT] trial).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Cardiac pacemaking in the sinoatrial node

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Specific bradycardic agents--a novel pharmacological class?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

What keeps us ticking: a funny current, a calcium clock, or both?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Organisation of the mouse sinoatrial node: structure and expression of HCN channels

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Long-term safety and efficacy of ivabradine in patients with chronic stable angina

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Heart rate reduction by inhibition of If or by beta-blockade has different effects on postsystolic wall thickening

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Conversion of post-systolic wall thickening into ejectional thickening by selective heart rate reduction during myocardial stunning

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Structure and function of cardiac pacemaker channels

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

A family of hyperpolarization-activated mammalian cation channels

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Two pacemaker channels from human heart with profoundly different activation kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Dynamic interactions of an intracellular Ca2+ clock and membrane ion channel clock underlie robust initiation and regulation of cardiac pacemaker function

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Funny current provides a relatively modest contribution to spontaneous beating rate regulation of human and rabbit sinoatrial node cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Genesis and regulation of the heart automaticity.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

ICI D7288, a novel sinoatrial node modulator.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

The relationship between resting heart rate and all-cause, cardiovascular and cancer mortality

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Beneficial effects of delayed ivabradine treatment on cardiac anatomical and electrical remodeling in rat severe chronic heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Heart rate reduction during exercise-induced myocardial ischaemia and stunning.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Long-term heart rate reduction induced by the selective I(f) current inhibitor ivabradine improves left ventricular function and intrinsic myocardial structure in congestive heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Molecular physiology of cardiac repolarization

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Heart rate as an independent risk factor for cardiovascular disease: current evidence and basic mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

High heart rate: a risk factor for cardiovascular death in elderly men

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Queer current and pacemaker: the hyperpolarization-activated cation current in neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Regulation of gating and rundown of HCN hyperpolarization-activated channels by exogenous and endogenous PIP2

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Heart rate reduction by I(f)-channel inhibition and its potential role in heart failure with reduced and preserved ejection fraction

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Antianginal efficacy and safety of ivabradine compared with amlodipine in patients with stable effort angina pectoris: a 3-month randomised, double-blind, multicentre, noninferiority trial

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Effect of HCN channel inhibition on retinal morphology and function in normal and dystrophic rodents

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Functional remodeling in post-myocardial infarcted rats: focus on beta-adrenoceptor subtypes.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Electrophysiologic changes in heart failure: focus on pacemaker channels

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Electrophysiological study of alinidine in voltage clamped rabbit sino-atrial node cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

I f inhibition with ivabradine : electrophysiological effects and safety

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Alinidine modifies the pacemaker current in sheep Purkinje fibers

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Oxygen consumption of the heart. Newer concepts of its multifactoral determination

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Bradycardic and proarrhythmic properties of sinus node inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Molecular basis of funny current (If) in normal and failing human heart.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Rationale and design of a randomized, double-blind, placebo-controlled outcome trial of ivabradine in chronic heart failure: the Systolic Heart Failure Treatment with the I(f) Inhibitor Ivabradine Trial (SHIFT).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Efficacy of ivabradine, a new selective I(f) inhibitor, compared with atenolol in patients with chronic stable angina

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Efficacy of the I(f) current inhibitor ivabradine in patients with chronic stable angina receiving beta-blocker therapy: a 4-month, randomized, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Differential Expression of Ion Channel Transcripts in Atrial Muscle and Sinoatrial Node in Rabbit

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Use-dependent inhibition of hHCN4 by ivabradine and relationship with reduction in pacemaker activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Stereospecific in vitro and in vivo effects of the new sinus node inhibitor (+)-S 16257

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Electrophysiological effects of S 16257, a novel sino-atrial node modulator, on rabbit and guinea-pig cardiac preparations: comparison with UL-FS 49

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Vascular endothelial ageing, heartbeat after heartbeat

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Ivabradine induces an increase in ventricular fibrillation threshold during acute myocardial ischemia: an experimental study

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Pharmacological influence of specific bradycardic agents on the pacemaker current of sheep cardiac Purkinje fibres. A comparison between three different molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Use- and frequency-dependent blockade by UL-FS 49 of the if pacemaker current in sheep cardiac Purkinje fibres

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Use-dependent blockade of cardiac pacemaker current (If) by cilobradine and zatebradine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Relative importance of funny current in human versus rabbit sinoatrial node

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Pacemaker current (I(f)) in the human sinoatrial node.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

The discovery of the selective I(f) current inhibitor ivabradine. A new therapeutic approach to ischemic heart disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Anti-Ischemic Effects of Ivabradine, a Selective Heart Rate-Reducing Agent, in Exercise-Induced Myocardial Ischemia in Pigs

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Regulation of basal and reserve cardiac pacemaker function by interactions of cAMP-mediated PKA-dependent Ca2+ cycling with surface membrane channels

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Rhythmic Ca2+ oscillations drive sinoatrial nodal cell pacemaker function to make the heart tick.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

HCN channels: structure, cellular regulation and physiological function

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Structural remodelling of the sinoatrial node in obese old rats

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure model

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2810%2959003-3

7 January 2021

10.1016/S1054-3589(10)59003-3

Identifiers

DOI

1 reference

23 August 2017

1 reference