(Q37800357)

23 August 2017

Central mechanisms of pathological pain (English)

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23 August 2017

Rohini Kuner

1

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PubMed ID

20948531

23 August 2017

language of work or name

English

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publication date

14 October 2010

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23 August 2017

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23 August 2017

16

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23 August 2017

1258-1266

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23 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nm.2231

23 August 2017

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cites work

Specific involvement in neuropathic pain of AMPA receptors and adapter proteins for the GluR2 subunit

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12 December 2020

Mechanisms of pain in arthritis

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12 December 2020

Allodynia and hyperalgesia in diabetic rats are mediated by GABA and depletion of spinal potassium-chloride co-transporters

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12 December 2020

Supraspinal glial-neuronal interactions contribute to descending pain facilitation

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12 December 2020

The liberation of fractalkine in the dorsal horn requires microglial cathepsin S.

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12 December 2020

Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain.

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12 December 2020

Stably maintained dendritic spines are associated with lifelong memories

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12 December 2020

Superficial NK1-expressing neurons control spinal excitability through activation of descending pathways

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12 December 2020

Protease-activated receptor-1 and platelet-derived growth factor in spinal cord neurons are implicated in neuropathic pain after nerve injury

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12 December 2020

Neuronal plasticity: increasing the gain in pain

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12 December 2020

A-fibers mediate mechanical hyperesthesia and allodynia and C-fibers mediate thermal hyperalgesia in a new model of causalgiform pain disorders in rats

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12 December 2020

Chronic pain and medullary descending facilitation

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12 December 2020

GlyR alpha3: an essential target for spinal PGE2-mediated inflammatory pain sensitization

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12 December 2020

Evidence for a central component of post-injury pain hypersensitivity

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12 December 2020

Neuropathic pain: a clinical perspective

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12 December 2020

AMPA receptor–PDZ interactions in facilitation of spinal sensory synapses

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12 December 2020

Loose ligation of the rat sciatic nerve elicits early accumulation of Shank1 protein in the post-synaptic density of spinal dorsal horn neurons

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12 December 2020

Differential mechanisms of CRF1 and CRF2 receptor functions in the amygdala in pain-related synaptic facilitation and behavior

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12 December 2020

Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway

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12 December 2020

Activity-dependent potentiation of calcium signals in spinal sensory networks in inflammatory pain states

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12 December 2020

Hematopoietic colony–stimulating factors mediate tumor-nerve interactions and bone cancer pain

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12 December 2020

Thrombin Inhibits NMDA‐Mediated Nociceptive activity in the Mouse: Possible Mediation by Endothelin

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12 December 2020

Neuropathic pain memory is maintained by Rac1-regulated dendritic spine remodeling after spinal cord injury.

1 reference

12 December 2020

Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain

1 reference

12 December 2020

Regional gray matter density changes in brains of patients with irritable bowel syndrome

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12 December 2020

Tuning thalamic firing modes via simultaneous modulation of T- and L-type Ca2+ channels controls pain sensory gating in the thalamus

1 reference

12 December 2020

Nociceptor sensitization in pain pathogenesis

1 reference

12 December 2020

The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory pain

1 reference

12 December 2020

Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain

1 reference

12 December 2020

Topical bicuculline to the rat spinal cord induces highly localized allodynia that is mediated by spinal prostaglandins

1 reference

12 December 2020

Pain mechanisms: a new theory

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12 December 2020

BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

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12 December 2020

Neurotrophins: mediators and modulators of pain.

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12 December 2020

Rho GTPases in neuronal morphogenesis

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12 December 2020

Mammalian G proteins and their cell type specific functions

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12 December 2020

Noradrenaline modulates transmission at a central synapse by a presynaptic mechanism.

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12 December 2020

Central sensitization and LTP: do pain and memory share similar mechanisms?

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12 December 2020

Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity

1 reference

12 December 2020

Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain

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12 December 2020

Actin in dendritic spines: connecting dynamics to function

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12 December 2020

Supraspinal brain-derived neurotrophic factor signaling: a novel mechanism for descending pain facilitation.

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12 December 2020

Pain modulation: expectation, opioid analgesia and virtual pain.

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12 December 2020

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

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12 December 2020

Silent glutamatergic synapses and nociception in mammalian spinal cord.

1 reference

12 December 2020

Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC

1 reference

12 December 2020

DREAM is a critical transcriptional repressor for pain modulation

1 reference

12 December 2020

Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons

1 reference

12 December 2020

Mice lacking central serotonergic neurons show enhanced inflammatory pain and an impaired analgesic response to antidepressant drugs

1 reference

12 December 2020

Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury.

1 reference

12 December 2020

Characterization of sensory neuron subpopulations selectively expressing green fluorescent protein in phosphodiesterase 1C BAC transgenic mice

1 reference

12 December 2020

Synaptic plasticity in the amygdala in a model of arthritic pain: differential roles of metabotropic glutamate receptors 1 and 5

1 reference

12 December 2020

Descending control of nociception: Specificity, recruitment and plasticity

1 reference

12 December 2020

Pancreatic neuropathy and neuropathic pain--a comprehensive pathomorphological study of 546 cases

1 reference

12 December 2020

In vivo recruitment by painful stimuli of AMPA receptor subunits to the plasma membrane of spinal cord neurons

1 reference

12 December 2020

Molecular depletion of descending serotonin unmasks its novel facilitatory role in the development of persistent pain

1 reference

12 December 2020

MRI structural brain changes associated with sensory and emotional function in a rat model of long-term neuropathic pain

1 reference

12 December 2020

Synaptic plasticity in spinal lamina I projection neurons that mediate hyperalgesia

1 reference

12 December 2020

The kv4.2 potassium channel subunit is required for pain plasticity.

1 reference

12 December 2020

Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis

1 reference

12 December 2020

Current challenges in glia-pain biology

1 reference

12 December 2020

Role of neurotransmitters in sensitization of pain responses

1 reference

12 December 2020

Removal of GABAergic inhibition facilitates polysynaptic A fiber-mediated excitatory transmission to the superficial spinal dorsal horn

1 reference

12 December 2020

Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling

1 reference

12 December 2020

Central serotonergic neurons are differentially required for opioid analgesia but not for morphine tolerance or morphine reward

1 reference

12 December 2020

Brain gray matter decrease in chronic pain is the consequence and not the cause of pain.

1 reference

12 December 2020

Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord.

1 reference

12 December 2020

Spread of excitation across modality borders in spinal dorsal horn of neuropathic rats

1 reference

12 December 2020

Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain

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12 December 2020

Neuropathic sensitization of behavioral reflexes and spinal NMDA receptor/CaM kinase II interactions are disrupted in PSD-95 mutant mice

1 reference

12 December 2020

Roles of the AMPA receptor subunit GluA1 but not GluA2 in synaptic potentiation and activation of ERK in the anterior cingulate cortex

1 reference

12 December 2020

Activation of the opioidergic descending pain control system underlies placebo analgesia.

1 reference

12 December 2020

Activation of extracellular signal-regulated kinase in the anterior cingulate cortex contributes to the induction and expression of affective pain

1 reference

12 December 2020

Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit

1 reference

12 December 2020

Thalamic NMDA receptors modulate inflammation-produced hyperalgesia in the rat.

1 reference

12 December 2020

Psychological and neural mechanisms of the affective dimension of pain

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12 December 2020

Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine

1 reference

12 December 2020

Unmasking the tonic-aversive state in neuropathic pain

1 reference

12 December 2020

Regulation of spine and synapse formation by activity-dependent intracellular signaling pathways

1 reference

12 December 2020

Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors

1 reference

12 December 2020

Reversal of pathological pain through specific spinal GABAA receptor subtypes.

1 reference

12 December 2020

Dynamic balance of metabotropic inputs causes dorsal horn neurons to switch functional states

1 reference

12 December 2020

Tissue plasminogen activator in primary afferents induces dorsal horn excitability and pain response after peripheral nerve injury

1 reference

12 December 2020

Paclitaxel- and vincristine-evoked painful peripheral neuropathies: loss of epidermal innervation and activation of Langerhans cells

1 reference

12 December 2020

Homer: a link between neural activity and glutamate receptor function

1 reference

12 December 2020

The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain

1 reference

12 December 2020

Morphing voxels: the hype around structural imaging of headache patients

1 reference

12 December 2020

Peripheral axotomy induces only very limited sprouting of coarse myelinated afferents into inner lamina II of rat spinal cord

1 reference

12 December 2020

Synaptic strengthening through activation of Ca2+-permeable AMPA receptors

1 reference

12 December 2020

An improved behavioural assay demonstrates that ultrasound vocalizations constitute a reliable indicator of chronic cancer pain and neuropathic pain

1 reference

12 December 2020

Nociceptive tuning by stem cell factor/c-Kit signaling

1 reference

12 December 2020

Medullary pain facilitating neurons mediate allodynia in headache-related pain

1 reference

12 December 2020

Functional interactions between tumor and peripheral nerve: changes in excitability and morphology of primary afferent fibers in a murine model of cancer pain

1 reference

12 December 2020

Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity.

1 reference

12 December 2020

Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons.

1 reference

12 December 2020

Models and mechanisms of hyperalgesia and allodynia

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12 December 2020

Dendritic spines: the stuff that memories are made of?

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12 December 2020

Both Ca2+-permeable and -impermeable AMPA receptors contribute to primary synaptic drive onto rat dorsal horn neurons

1 reference

12 December 2020

Spinal cord injury-induced attenuation of GABAergic inhibition in spinal dorsal horn circuits is associated with down-regulation of the chloride transporter KCC2 in rat.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.2231

1 reference

23 August 2017

1 reference

PubMed ID

20948531