(Q37800506)

20950328

23 August 2017

title

Role of spinal neurotransmitter receptors in itch: new insights into therapies and drug development (English)

1 reference

23 August 2017

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493876&resulttype=core&format=json

14 May 2020

author name string

Ferda Cevikbas

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493876&resulttype=core&format=json

14 May 2020

Akihiko Ikoma

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493876&resulttype=core&format=json

14 May 2020

publication date

15 October 2010

1 reference

20950328

CNS Neuroscience & Therapeutics

23 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493876&resulttype=core&format=json

14 May 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493876&resulttype=core&format=json

14 May 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493876&resulttype=core&format=json

14 May 2020

page(s)

742-749

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493876&resulttype=core&format=json

14 May 2020

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Norbinaltorphimine, a selective kappa-opioid receptor antagonist, induces an itch-associated response in mice

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Nalfurafine prevents 5'-guanidinonaltrindole- and compound 48/80-induced spinal c-fos expression and attenuates 5'-guanidinonaltrindole-elicited scratching behavior in mice

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Kappa-opioid system in uremic pruritus: multicenter, randomized, double-blind, placebo-controlled clinical studies

21 January 2018

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Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: a Phase III, randomized, double-blind, placebo-controlled study.

21 January 2018

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Gastrin-releasing peptide receptor as a molecular target in experimental anticancer therapy

21 January 2018

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Gastrin-releasing peptide: different forms, different functions.

21 January 2018

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Loss of bombesin-induced feeding suppression in gastrin-releasing peptide receptor-deficient mice

21 January 2018

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A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord

21 January 2018

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Cellular basis of itch sensation

21 January 2018

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Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus

21 January 2018

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A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons

21 January 2018

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Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family

21 January 2018

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21 January 2018

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Plasticity of NMDA receptor NR2B subunit in memory and chronic pain

21 January 2018

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Neuronal plasticity: increasing the gain in pain

21 January 2018

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Neuronal sensitization for histamine-induced itch in lesional skin of patients with atopic dermatitis

21 January 2018

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Painful stimuli evoke itch in patients with chronic pruritus: central sensitization for itch

21 January 2018

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NMDA antagonists and neuropathic pain--multiple drug targets and multiple uses

21 January 2018

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Ketamine in chronic pain management: an evidence-based review

21 January 2018

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Effect of ketamine, an NMDA receptor inhibitor, in acute and chronic orofacial pain

21 January 2018

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Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn.

21 January 2018

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Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

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21 January 2018

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Treatment of neuropathic pain: an overview of recent guidelines

21 January 2018

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The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel

21 January 2018

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21 January 2018

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21 January 2018

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Brachioradial pruritus: response to treatment with gabapentin

21 January 2018

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21 January 2018

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21 January 2018

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Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P

21 January 2018

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Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice

21 January 2018

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Occurrence of substance P, vasoactive intestinal peptide, and calcitonin gene-related peptide in dermographism and cold urticaria

21 January 2018

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Flare and Itch Induced by Substance P in Human Skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

How important are NK1 receptors for influencing microvascular inflammation and itch in the skin? Studies using Phoneutria nigriventer venom.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Immunohistochemical localization of substance P receptor in the central nervous system of the adult rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

A quantitative and morphological study of projection neurons in lamina I of the rat lumbar spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Study of the analgesic effect of lanepitant in patients with osteoarthritis pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Lanepitant, an NK-1 antagonist, in migraine prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Dose-response study of the analgesic effect of lanepitant in patients with painful diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Aprepitant as an antipruritic agent?

21 January 2018

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Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategy

21 January 2018

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Kinins in pain and inflammation.

21 January 2018

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Kinin receptors in pain and inflammation

21 January 2018

1 reference

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Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission.

21 January 2018

1 reference

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Reduction of sodium deoxycholic acid-induced scratching behaviour by bradykinin B2 receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Potent pruritogenic action of tryptase mediated by PAR-2 receptor and its involvement in anti-pruritic effect of nafamostat mesilate in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Scratching behavior in mice induced by the proteinase-activated receptor-2 agonist, SLIGRL-NH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Different dorsal horn neurons responding to histamine and allergic itch stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Excitation of mouse superficial dorsal horn neurons by histamine and/or PAR-2 agonist: potential role in itch

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

The role of kinin B1 and B2 receptors in the scratching behaviour induced by proteinase-activated receptor-2 agonists in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

5-Hydroxytryptamine (5-HT)2 receptor involvement in acute 5-HT-evoked scratching but not in allergic pruritus induced by dinitrofluorobenzene in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Responses of superficial dorsal horn neurons to intradermal serotonin and other irritants: comparison with scratching behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Activation of superficial dorsal horn neurons in the mouse by a PAR-2 agonist and 5-HT: potential role in itch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Serotonin receptor antagonists for the prevention and treatment of pruritus, nausea, and vomiting in women undergoing cesarean delivery with intrathecal morphine: a systematic review and meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Effect of prophylactic 5-HT3 receptor antagonists on pruritus induced by neuraxial opioids: a quantitative systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Systemic morphine produce antinociception mediated by spinal 5-HT7, but not 5-HT1A and 5-HT2 receptors in the spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Spinal 5-HT7 receptors play an important role in the antinociceptive and antihyperalgesic effects of tramadol and its metabolite, O-Desmethyltramadol, via activation of descending serotonergic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Histamine, histamine receptors and their role in immune pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Histamine H4 receptor antagonism reduces hapten-induced scratching behaviour but not inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Involvement of histamine H3 receptors in scratching behaviour in mast cell-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

The binding of [3H]mepyramine to histamine H1 receptors in guinea-pig brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Localization of opiate and histamine H1-receptors in the primate sensory ganglia and spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Histamine H1 receptors in the brain and spinal cord of the cat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Involvement of the histaminergic system in the nociceptin-induced pain-related behaviors in the mouse spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Intrathecally-administered histamine facilitates nociception through tachykinin NK1 and histamine H1 receptors: a study in histidine decarboxylase gene knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Enhanced antinociception by intrathecally-administered morphine in histamine H1 receptor gene knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Enhanced antinociceptive effects of morphine in histamine H2 receptor gene knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Enhanced morphine-induced antinociception in histamine H3 receptor gene knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Localization of histamine H4 receptors in the central nervous system of human and rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

The use of kinin B1 and B2 receptor knockout mice and selective antagonists to characterize the nociceptive responses caused by kinins at the spinal level

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00201.X

Transmission of chronic nociception by spinal neurons expressing the substance P receptor

21 January 2018

1 reference

12 December 2020

Itch-associated response induced by intradermal serotonin through 5-HT2 receptors in mice

1 reference

12 December 2020

Intrathecally administered spermine produces the scratching, biting and licking behaviour in mice

1 reference

12 December 2020

Acute Effects of Substance P and Calcitonin Gene-Related Peptide in Human Skin – A Microdialysis Study

1 reference

12 December 2020

Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway

1 reference

12 December 2020

GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus monkeys

1 reference

12 December 2020

Pain as a complication of use of opiate antagonists for symptom control in cholestasis

1 reference

12 December 2020

The spinal and peripheral roles of bradykinin and prostaglandins in nociceptive processing in the rat

1 reference

12 December 2020

Peripheral and central mediators of itch

1 reference

12 December 2020

The pruritus of cholestasis

1 reference

12 December 2020

Role of substance P on histamine H(3) antagonist-induced scratching behavior in mice

1 reference

12 December 2020

Bradykinin is a potent pruritogen in atopic dermatitis: A switch from pain to itch

1 reference

12 December 2020

Neuropeptides in skin from patients with atopic dermatitis: an immunohistochemical study

1 reference

12 December 2020

Efficacy of pregabalin in the management of cetuximab-related itch

1 reference

12 December 2020

Itch without pain—a labeled line for itch sensation?

1 reference

12 December 2020

Mechanism of action of antipruritic drugs

1 reference

12 December 2020

Histamine Release during Morphine and Fentanyl Anesthesia

1 reference

12 December 2020

Rostral spread of epidural morphine.

1 reference

12 December 2020

Histamine receptors in human skin: indirect evidence

1 reference

12 December 2020

The correlation between the distribution of the NK1 receptor and the actions of tachykinin agonists in the dorsal horn of the rat indicates that substance P does not have a functional role on substantia gelatinosa (lamina II) neurons

1 reference

12 December 2020

Nonopioid mechanism of morphine modulation of the activation of 5-hydroxytryptamine type 3 receptors.

1 reference

12 December 2020

The types of neuron in spinal dorsal horn which possess neurokinin-1 receptors

1 reference

12 December 2020

The medullary dorsal horn. A site of action of morphine in producing facial scratching in monkeys

1 reference

12 December 2020

Randomised crossover trial of naltrexone in uraemic pruritus

1 reference

12 December 2020

Specific C-receptors for itch in human skin.

1 reference

12 December 2020

Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor

1 reference

12 December 2020

Opiate and H1 antagonist effects on histamine induced pruritus and alloknesis

1 reference

12 December 2020

Intraepidermal nerve fiber expression of calcitonin gene-related peptide, vasoactive intestinal peptide and substance P in psoriasis

1 reference

12 December 2020

Spinal NMDA receptor involvement in expansion of dorsal horn neuronal receptive field area produced by intracutaneous histamine

1 reference

12 December 2020

Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients

1 reference

12 December 2020

Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice

1 reference

12 December 2020

10.1111/J.1755-5949.2010.00201.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493876&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493876&resulttype=core&format=json

14 May 2020

20950328

1 reference