(Q37804266)

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Is the toxicity of cysteine conjugates formed during mercapturic acid biosynthesis relevant to the toxicity of covalently bound drug residues?

scientific article published on January 1990

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scholarly article

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Europe PubMed Central

23 August 2017

1 reference

Europe PubMed Central

Is the toxicity of cysteine conjugates formed during mercapturic acid biosynthesis relevant to the toxicity of covalently bound drug residues? (English)

1 reference

Europe PubMed Central

23 August 2017

1 reference

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Stevens JL

1

1 reference

Europe PubMed Central

23 August 2017

Wallin A

2

1 reference

Europe PubMed Central

23 August 2017

language of work or name

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publication date

1 January 1990

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Europe PubMed Central

23 August 2017

Drug Metabolism Reviews

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Europe PubMed Central

23 August 2017

22

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Europe PubMed Central

23 August 2017

6-8

1 reference

Europe PubMed Central

23 August 2017

617-635

1 reference

Europe PubMed Central

23 August 2017

Mutagenicity of nitrofuran derivatives: Review

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

Formation of toxic metabolites from drugs and other xenobiotics by glutathione conjugation

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

Studies on the mechanism of nephrotoxicity and nephrocarcinogenicity of halogenated alkenes

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

Biochemistry of sulfur-containing amino acids

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

Glutathione S-conjugate formation from 1-chloro-2,4-dinitrobenzene and biliary S-conjugate excretion in the perfused rat liver

1 reference

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21 January 2018

The metabolism and disposition of hexachloro-1:3-butadiene in the rat and its relevance to nephrotoxicity

1 reference

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21 January 2018

Enterohepatic circulation in formation of propachlor (2-chloro-N-isopropylacetanilide) metabolites in the rat

1 reference

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21 January 2018

Biliary Excretion of Drugs and Other Xenobiotics

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

Methylthlolated Metabolites

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

Metabolism of polycyclic compounds. 18. The secretion of metabolites of naphthalene, 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene in rat bile

1 reference

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21 January 2018

Effect of the organic acid transport inhibitor probenecid on renal cortical uptake and proximal tubular toxicity of hexachloro-1,3-butadiene and its conjugates.

1 reference

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21 January 2018

Differential toxicity as a result of apical and basolateral treatment of LLC-PK1 monolayers with S-(1,2,3,4,4-pentachlorobutadienyl)glutathione and N-acetyl-S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine

1 reference

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21 January 2018

Sugar, Amino Acid, and NA+ Cotransport in the Proximal Tubule

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

Drug transport in intestine, liver and kidney

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

S-[2-(N7-guanyl)ethyl]glutathione, the major DNA adduct formed from 1,2-dibromoethane.

1 reference

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21 January 2018

Formation of S-[2-(N7-guanyl)ethyl] adducts by the postulated S-(2-chloroethyl)cysteinyl and S-(2-chloroethyl)glutathionyl conjugates of 1,2-dichloroethane

1 reference

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21 January 2018

Hepatic low-level chemiluminescence during redox cycling of menadione and the menadione-glutathione conjugate: relation to glutathione and NAD(P)H:quinone reductase (DT-diaphorase) activity.

1 reference

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21 January 2018

Bacterial cysteine conjugate beta-lyase and the metabolism of cysteine S-conjugates: structural requirements for the cleavage of S-conjugates and the formation of reactive intermediates

1 reference

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21 January 2018

Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2,2-trichlorovinyl)-L-cysteine formed by cysteine conjugate beta-lyase

1 reference

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21 January 2018

Enzymatic transformation of mercapturic acids derived from halogenated alkenes to reactive and mutagenic intermediates

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

Structure/activity studies of the nephrotoxic and mutagenic action of cysteine conjugates of chloro- and fluoroalkenes

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

The mechanism of pentachlorobutadienyl-glutathione nephrotoxicity studied with isolated rat renal epithelial cells

1 reference

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21 January 2018

Purification and characterization of human hepatic cysteine-conjugate beta-lyase

1 reference

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21 January 2018

The metabolism of bromazepam in the rat—identification of mercapturic acid and its conversion in vitro to methylthio-bromazepam

1 reference

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21 January 2018

Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

Bioactivation mechanism of the cytotoxic and nephrotoxic S-conjugate S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

Mutagenicity of hexachloro-1,3-butadiene and its S-conjugates in the Ames test--role of activation by the mercapturic acid pathway in its nephrocarcinogenicity

1 reference

https://api.crossref.org/works/10.3109%2F03602539008991457

21 January 2018

Identifiers

10.3109/03602539008991457

1 reference

Europe PubMed Central

23 August 2017

1 reference

Europe PubMed Central

23 August 2017

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