(Q37810487)

23 August 2017

Amphotericin B membrane action: role for two types of ion channels in eliciting cell survival and lethal effects (English)

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23 August 2017

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B Eleazar Cohen

1

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23 August 2017

18 November 2010

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23 August 2017

20

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Journal of Membrane Biology

inferred from page(s)

published in

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23 August 2017

238

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23 August 2017

1-3

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23 August 2017

1-20

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https://scigraph.springernature.com/pub.10.1007/s00232-010-9313-y

23 August 2017

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Effect of increasing intravesicular pH on nitrite production and leishmanicidal activity of activated macrophages

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Recovery of hepatocytes from attack by the pore former amphotericin B.

21 January 2018

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Stimulatory, permeabilizing, and toxic effects of amphotericin B on L cells

21 January 2018

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A survey of the interaction of calcium ions with mitochondria from different tissues and species

21 January 2018

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Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase

21 January 2018

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Ceramide signaling in apoptosis

21 January 2018

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Analysis of amphotericin B-induced cell signaling with chemical inhibitors of signaling molecules

21 January 2018

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Structure of lipid bilayers

21 January 2018

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Enhanced action of amphotericin B on Leishmania mexicana resulting from heat transformation

21 January 2018

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Comparative analysis of cholesterol sensitivity of Kir channels: role of the CD loop

21 January 2018

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Role of cell defense against oxidative damage in the resistance of Candida albicans to the killing effect of amphotericin B.

21 January 2018

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Microarray analysis of amphotericin B-treated THP-1 monocytic cells identifies unique gene expression profiles among lipid and non-lipid drug formulations

21 January 2018

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Ca2+ transport by digitonin-permeabilized Leishmania donovani. Effects of Ca2+, pentamidine and WR-6026 on mitochondrial membrane potential in situ

21 January 2018

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An amino acid channel activated by hypotonically induced swelling of Leishmania major promastigotes

21 January 2018

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Effect of amphotericin B on cholesterol-containing liposomes of egg phosphatidylcholine and didocosenoyl phosphatidylcholine. A refinement of the model for the formation of pores by amphotericin B in membranes

21 January 2018

1 reference

12 December 2020

Pharmacokinetics, excretion, and mass balance of liposomal amphotericin B (AmBisome) and amphotericin B deoxycholate in humans

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12 December 2020

Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane

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12 December 2020

Effect of Line Tension on the Lateral Organization of Lipid Membranes

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12 December 2020

Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites

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12 December 2020

Scrambling of phospholipids activates red cell membrane cholesterol

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12 December 2020

Amphotericin B Channels in the Bacterial Membrane: Role of Sterol and Temperature

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12 December 2020

Osmosis: a bimodal theory with implications for symmetry.

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12 December 2020

Enhancement of nitric oxide synthesis by macrophages represents an additional mechanism of action for amphotericin B.

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12 December 2020

A second osmosensing signal transduction pathway in yeast. Hypotonic shock activates the PKC1 protein kinase-regulated cell integrity pathway

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12 December 2020

A sequential mechanism for the formation of aqueous channels by amphotericin B in liposomes. The effect of sterols and phospholipid composition

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12 December 2020

Transcription profiling of cyclic AMP signaling in Candida albicans.

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12 December 2020

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12 December 2020

The effect of amphotericin B on the K-channel activity of MDCK cells

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12 December 2020

Structure, composition, and peptide binding properties of detergent soluble bilayers and detergent resistant rafts

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12 December 2020

Antifungal susceptibility testing: practical aspects and current challenges

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12 December 2020

Inducible defense mechanism against nitric oxide in Candida albicans

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12 December 2020

Pore-forming toxins and cellular non-immune defenses (CNIDs).

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12 December 2020

Genome-wide fitness and expression profiling implicate Mga2 in adaptation to hydrogen peroxide

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12 December 2020

Structural determinants of water permeability through the lipid membrane.

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12 December 2020

Response of the Saccharomyces cerevisiae Mpk1 mitogen-activated protein kinase pathway to increases in internal turgor pressure caused by loss of Ppz protein phosphatases

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12 December 2020

A signal-switch hypothesis for cross-regulation of cytokine and TLR signalling pathways

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12 December 2020

Actin-induced hyperactivation of the Ras signaling pathway leads to apoptosis in Saccharomyces cerevisiae.

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12 December 2020

Amphotericin B-induced renal tubular cell injury is mediated by Na+ Influx through ion-permeable pores and subsequent activation of mitogen-activated protein kinases and elevation of intracellular Ca2+ concentration.

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12 December 2020

Cell wall integrity signaling in Saccharomyces cerevisiae

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12 December 2020

Secretion of proinflammatory cytokines and chemokines during amphotericin B exposure is mediated by coactivation of toll-like receptors 1 and 2.

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12 December 2020

Dynamic domain formation in membranes: Thickness-modulation-induced phase separation

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12 December 2020

The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response

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12 December 2020

Molecular aspects of the interaction between amphotericin B and a phospholipid bilayer: molecular dynamics studies.

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12 December 2020

Protein sensors for membrane sterols

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12 December 2020

In vitro activity of nystatin compared with those of liposomal nystatin, amphotericin B, and fluconazole against clinical Candida isolates

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12 December 2020

Antimonial-induced Increase in Intracellular Ca2+ through Non-selective Cation Channels in the Host and the Parasite Is Responsible for Apoptosis of Intracellular Leishmania donovani Amastigotes

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12 December 2020

Formation of two different types of ion channels by amphotericin B in human erythrocyte membranes.

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12 December 2020

Modifications of pH and K+ gradients in Candida albicans blastospores induced by amphotericin B. A 31P NMR and K+ atomic absorption study

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12 December 2020

One-sided action of amphotericin B on cholesterol-containing membranes is determined by its self-association in the medium

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12 December 2020

Oxidative and amphotericin B-mediated cell death in the opportunistic pathogen Aspergillus fumigatus is associated with an apoptotic-like phenotype

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12 December 2020

Concentration- and time-dependence of amphotericin-B induced permeability changes across ergosterol-containing liposomes

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12 December 2020

Monolayer interactions of individual lecithins with natural sterols

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12 December 2020

Visualizing association of N-ras in lipid microdomains: influence of domain structure and interfacial adsorption

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12 December 2020

GPI-anchored proteins and glycoconjugates segregate into lipid rafts in Kinetoplastida

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12 December 2020

The water and ionic permeability induced by polyene antibiotics across plasma membrane vesicles from Leishmania sp.

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12 December 2020

Nystatin-induced nitric oxide production in mouse macrophage-like cell line RAW264.7.

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12 December 2020

Temperature-dependent modes for the binding of the polyene antibiotic amphotericin B to human erythrocyte membranes. A circular dichroism study

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12 December 2020

The challenge of finding a cure for HIV infection

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12 December 2020

Model systems, lipid rafts, and cell membranes

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12 December 2020

The genetic landscape of a cell

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12 December 2020

Amphotericin B severely affects expression and activity of the endothelial constitutive nitric oxide synthase involving altered mRNA stability

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12 December 2020

Mesoscopic undulations and thickness fluctuations in lipid bilayers from molecular dynamics simulations

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12 December 2020

The bound states of amphipathic drugs in lipid bilayers: study of curcumin

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12 December 2020

Calcium and cell death: the mitochondrial connection.

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12 December 2020

Differential expression of genes encoding immunomodulatory proteins in response to amphotericin B in human mononuclear cells identified by cDNA microarray analysis

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12 December 2020

Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans

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12 December 2020

Intracellular Na+ controls cell surface expression of Na,K-ATPase via a cAMP-independent PKA pathway in mammalian kidney collecting duct cells

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12 December 2020

The diploid genome sequence of Candida albicans

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12 December 2020

Interrelationships among quinidine, amiloride, and lithium as inhibitors of the renal Na+-H+ exchanger

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12 December 2020

Integrative model of the response of yeast to osmotic shock

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12 December 2020

Transcriptional regulation of the human iNOS gene by IL-1beta in endothelial cells

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12 December 2020

Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay

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12 December 2020

The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism

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12 December 2020

Identification of the structural elements of amphotericin B and other polyene macrolide antibiotics of the hepteane group influencing the ionic selectivity of the permeability pathways formed in the red cell membrane

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12 December 2020

Identification of a conserved domain of the HIV-1 transmembrane protein gp41 which interacts with cholesteryl groups

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12 December 2020

Down-regulation of fatty acid synthase increases the resistance of Saccharomyces cerevisiae cells to H2O2.

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12 December 2020

Amiloride and the regulation of NF-kappaB: an unsung crosstalk and missing link between fluid dynamics and oxidative stress-related inflammation--controversy or pseudo-controversy?

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12 December 2020

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

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12 December 2020

Changes in the proteome of Candida albicans in response to azole, polyene, and echinocandin antifungal agents

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12 December 2020

Polyene antibiotic-sterol interactions in membranes of Acholeplasma laidlawii cells and lecithin liposomes. 3. Molecular structure of the polyene antibiotic-cholesterol complexes

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12 December 2020

NO-mediated apoptosis in yeast.

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12 December 2020

Proton permeability induced by polyene antibiotics. A plausible mechanism for their inhibition of maltose fermentation in yeast

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12 December 2020

Central roles of small GTPases in the development of cell polarity in yeast and beyond

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12 December 2020

Amphotericins A and B, antifungal antibiotics produced by a streptomycete. I. In vitro studies

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12 December 2020

Thermodynamic analysis of the permeability of biological membranes to non-electrolytes

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12 December 2020

On the mechanism of ionic regulation of apoptosis: would the Na+/K+-ATPase please stand up?

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12 December 2020

Dimers of polyene antibiotic amphotericin B detected by means of fluorescence spectroscopy: molecular organization in solution and in lipid membranes

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12 December 2020

Measurement of the ADP:ATP ratio in human leukaemic cell lines can be used as an indicator of cell viability, necrosis and apoptosis.

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12 December 2020

Lipid and stress dependence of amphotericin B ion selective channels in sterol-free membranes

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12 December 2020

Spatial compartmentalization of tumor necrosis factor (TNF) receptor 1-dependent signaling pathways in human airway smooth muscle cells. Lipid rafts are essential for TNF-alpha-mediated activation of RhoA but dispensable for the activation of the NF

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12 December 2020

Amphotericin B kills unicellular leishmanias by forming aqueous pores permeable to small cations and anions

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12 December 2020

Methyl beta-cyclodextrin reduces accumulation of reactive oxygen species and cell death in yeast

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12 December 2020

The activity of amphotericin B against Candida albicans is not directly associated with extracellular calcium concentration

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12 December 2020

Amphotericin B-induced oxidative damage and killing of Candida albicans

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12 December 2020

Inhibition of HIV-1 Replication by Amphotericin B Methyl Ester

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12 December 2020

Revisiting an old antimicrobial drug: amphotericin B induces interleukin-1-converting enzyme as the main factor for inducible nitric-oxide synthase expression in activated endothelia

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12 December 2020

Ras pathway signaling accelerates programmed cell death in the pathogenic fungus Candida albicans

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12 December 2020

The polyene antibiotic amphotericin B acts as a Ca2+ ionophore in sterol-containing liposomes.

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12 December 2020

Assessment of the effect of amphotericin B on the vitality of Candida albicans.

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12 December 2020

Comparative transcriptome analysis reveals novel roles of the Ras and cyclic AMP signaling pathways in environmental stress response and antifungal drug sensitivity in Cryptococcus neoformans

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12 December 2020

Line tension and interaction energies of membrane rafts calculated from lipid splay and tilt

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12 December 2020

Apoptosis induced by environmental stresses and amphotericin B in Candida albicans.

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12 December 2020

Binding of antibiotic amphotericin B to lipid membranes: A1H NMR study

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12 December 2020

Complex formation of amphotericin B in sterol-containing membranes as evidenced by surface plasmon resonance.

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12 December 2020

Polyene macrolide antibiotic amphotericin B. Crystal structure of the N-iodoacetyl derivative

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12 December 2020

Areas of molecules in membranes consisting of mixtures

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12 December 2020

Rom2p, the Rho1 GTP/GDP exchange factor of Saccharomyces cerevisiae, can mediate stress responses via the Ras-cAMP pathway.

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12 December 2020

Lipid perturbations sensitize osmotic down-shock activated Ca2+ influx, a yeast "deletome" analysis

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12 December 2020

Possible mechanism of miltefosine-mediated death of Leishmania donovani

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12 December 2020

Heat-induced superaggregation of amphotericin B attenuates its ability to induce cytokine and chemokine production in the human monocytic cell line THP-1.

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12 December 2020

Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF

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12 December 2020

Amphotericin B-induced interleukin-1beta expression in human monocytic cells is calcium and calmodulin dependent

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12 December 2020

Determination of the effective hydrodynamic radii of small molecules by viscometry

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12 December 2020

Functions and metabolism of sphingolipids in Saccharomyces cerevisiae

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12 December 2020

Anticryptococcal effect of amphotericin B is mediated through macrophage production of nitric oxide.

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12 December 2020

Programmed cell death in the unicellular protozoan parasite Leishmania

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12 December 2020

Concentration and time dependence of amphotericin B-induced permeability changes across plasma membrane vesicles from Leishmania sp

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12 December 2020

Signalling mechanisms and oxidative stress in apoptosis

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12 December 2020

Osmotic flow in membrane pores of molecular size

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12 December 2020

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

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12 December 2020

Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae

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12 December 2020

Molecular order and dynamics of phosphatidylcholine bilayer membranes in the presence of cholesterol, ergosterol and lanosterol: a comparative study using 2H-, 13C- and 31P-NMR spectroscopy

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12 December 2020

The sodium/hydrogen exchanger: a possible mediator of immunity

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12 December 2020

Molecular properties of amphotericin B membrane channel: a molecular dynamics simulation.

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12 December 2020

In vitro and in vivo interactions between miltefosine and other antileishmanial drugs

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12 December 2020

Binding of antibiotic amphotericin B to lipid membranes: monomolecular layer technique and linear dichroism-FTIR studies

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12 December 2020

A microscopic interaction model of maximum solubility of cholesterol in lipid bilayers

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12 December 2020

Liposomal amphotericin B and leishmaniasis: dose and response

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12 December 2020

Influence of net charge on the aggregation and solubility behaviour of amphotericin B and its derivatives in aqueous media

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12 December 2020

Cholesterol and ion channels

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12 December 2020

The effect of sterol structure on the permeability of lipomes to glucose, glycerol and Rb+

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12 December 2020

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

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12 December 2020

Amphotericin B susceptibility testing ofCandida species by flow cytometry

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12 December 2020

The sodium-hydrogen exchanger NHE1 is an Akt substrate necessary for actin filament reorganization by growth factors

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12 December 2020

Bacterial cytotoxins, amphotericin B and local anesthetics enhance transbilayer mobility of phospholipids in erythrocyte membranes. Consequences for phospholipid asymmetry.

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12 December 2020

Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM.

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12 December 2020

Amphotericin-B-mediated reactivation of latent HIV-1 infection

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12 December 2020

Remodeling of global transcription patterns of Cryptococcus neoformans genes mediated by the stress-activated HOG signaling pathways

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12 December 2020

Increased calcium permeability is not responsible for the rapid lethal effects of amphotericin B on Leishmania sp.

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12 December 2020

Effect of the structure of natural sterols and sphingolipids on the formation of ordered sphingolipid/sterol domains (rafts). Comparison of cholesterol to plant, fungal, and disease-associated sterols and comparison of sphingomyelin, cerebrosides, a

1 reference

12 December 2020

Effect of cholesterol and ergosterol on the compressibility and volume fluctuations of phospholipid-sterol bilayers in the critical point region: a molecular acoustic and calorimetric study

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12 December 2020

The PPZ protein phosphatases are involved in the maintenance of osmotic stability of yeast cells

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12 December 2020

Aqueous pores created in thin lipid membranes by the polyene antibiotics nystatin and amphotericin B.

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12 December 2020

eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues.

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12 December 2020

Dissection of transient oxidative stress response in Saccharomyces cerevisiae by using DNA microarrays

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12 December 2020

Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis

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12 December 2020

A simple method of determining relative permeabilities of liposomes to non-electrolytes

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12 December 2020

Apoptosis in Leishmania species & its relevance to disease pathogenesis

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12 December 2020

Release of amphotericin B from delivery systems and its action against fungal and mammalian cells

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12 December 2020

Polyene antibiotics: relative degrees of in vitro cytotoxicity and potential effects on tubule phospholipid and ceramide content

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12 December 2020

Cellular activation by Ca2+ release from stores in the endoplasmic reticulum but not by increased free Ca2+ in the cytosol

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12 December 2020

Mechanism of blockage of amphotericin B channels in a lipid bilayer

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12 December 2020

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

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12 December 2020

Apoptosis in yeast: a new model system with applications in cell biology and medicine.

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12 December 2020

Direct interaction between amphotericin B and ergosterol in lipid bilayers as revealed by 2H NMR spectroscopy.

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12 December 2020

Kinetic study of interaction between [14C]amphotericin B derivatives and human erythrocytes: relationship between binding and induced K+ leak

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12 December 2020

Amiloride for the prevention of amphotericin B-induced hypokalemia and hypomagnesemia

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12 December 2020

Possible reason for preferential damage to renal tubular epithelial cells evoked by amphotericin B.

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12 December 2020

Membrane sterol depletion impairs miltefosine action in wild-type and miltefosine-resistant Leishmania donovani promastigotes

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12 December 2020

Liposomal amphotericin B: a review of its use as empirical therapy in febrile neutropenia and in the treatment of invasive fungal infections

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12 December 2020

Interactions of the drug amphotericin B with phospholipid membranes containing or not ergosterol: new insight into the role of ergosterol

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12 December 2020

How do the polyene macrolide antibiotics affect the cellular membrane properties?

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12 December 2020

Sizing the radius of the pore formed in erythrocytes and lipid vesicles by the toxin sticholysin I from the sea anemone Stichodactyla helianthus

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12 December 2020

Role of the Hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen Candida albicans

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12 December 2020

Single-length and double-length channels formed by nystatin in lipid bilayer membranes

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12 December 2020

Direct regulation of prokaryotic Kir channel by cholesterol

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12 December 2020

Na+, K+ and Cl- selectivity of the permeability pathways induced through sterol-containing membrane vesicles by amphotericin B and other polyene antibiotics

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12 December 2020

10.1007/S00232-010-9313-Y

Identifiers

DOI

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23 August 2017

1 reference

PubMed ID

21085940