(Q37810643)

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Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations. Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21087454%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations. Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21087454%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Inmaculada Moreno-Gimeno

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21087454%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21087454%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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Maria H Ledran

2

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Europe PubMed Central

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16 January 2020

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19 November 2010

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Europe PubMed Central

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16 January 2020

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Europe PubMed Central

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16 January 2020

277

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16 January 2020

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16 January 2020

5014-5025

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21087454%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Embryonic stem cell lines derived from human blastocysts

1 reference

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Human embryonic stem cell technologies and drug discovery

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Hematopoietic colony-forming cells derived from human embryonic stem cells

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Globin switches in yolk sac-like primitive and fetal-like definitive red blood cells produced from human embryonic stem cells.

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T lineage differentiation from human embryonic stem cells

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Human embryonic stem cell-derived NK cells acquire functional receptors and cytolytic activity

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Retroviral transduction of hematopoietic cells differentiated from human embryonic stem cell-derived CD45(neg)PFV hemogenic precursors

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Definitive-like erythroid cells derived from human embryonic stem cells coexpress high levels of embryonic and fetal globins with little or no adult globin

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Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro

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Derivation of normal macrophages from human embryonic stem (hES) cells for applications in HIV gene therapy

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Differentiation of human embryonic stem cells into immunostimulatory dendritic cells under feeder-free culture conditions.

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Pluripotent stem cells as source of dendritic cells for immune therapy

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Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy

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Inhibition of HIV-1 infection by a unique short hairpin RNA to chemokine receptor 5 delivered into macrophages through hematopoietic progenitor cell transduction

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Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

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Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

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Cancer regression in patients after transfer of genetically engineered lymphocytes

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Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

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Induced pluripotent stem cell lines derived from human somatic cells

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Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin

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Phenotypic correction of murine hemophilia A using an iPS cell-based therapy

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Extensive hematopoietic stem cell generation in the AGM region via maturation of VE-cadherin+CD45+ pre-definitive HSCs

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Fate tracing reveals the endothelial origin of hematopoietic stem cells

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In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

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Blood stem cells emerge from aortic endothelium by a novel type of cell transition.

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Evidence for a fruit fly hemangioblast and similarities between lymph-gland hematopoiesis in fruit fly and mammal aorta-gonadal-mesonephros mesoderm.

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A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula

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Haemangioblast commitment is initiated in the primitive streak of the mouse embryo

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The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

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Continuous single-cell imaging of blood generation from haemogenic endothelium.

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SCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast but not for its development

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Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

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The human placenta is a hematopoietic organ during the embryonic and fetal periods of development

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Human placenta is a potent hematopoietic niche containing hematopoietic stem and progenitor cells throughout development

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Human term placenta as a source of hematopoietic cells

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Wnt signaling promotes hematoendothelial cell development from human embryonic stem cells

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OP9 stroma augments survival of hematopoietic precursors and progenitors during hematopoietic differentiation from human embryonic stem cells

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Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures

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Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.

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Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells

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Hematopoietic development from human embryonic stem cell lines.

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Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation.

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Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression

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Comparison of human cord blood engraftment between immunocompromised mouse strains

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Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.

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Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients

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Bioluminescent imaging demonstrates that transplanted human embryonic stem cell-derived CD34(+) cells preferentially develop into endothelial cells

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Emerging use of stem cells in regenerative medicine.

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Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence

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Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

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Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures

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Clone- and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells

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Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

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Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection

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Epigenetic memory in induced pluripotent stem cells

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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

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Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

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