(Q37811961)

23 August 2017

title

In vitro and in vivo evidence of the importance of organic anion transporters (OATs) in drug therapy (English)

1 reference

23 August 2017

In Vitro and In Vivo Evidence of the Importance of Organic Anion Transporters (OATs) in Drug Therapy (English)

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

2 September 2024

author name string

Gerhard Burckhardt

1

1 reference

23 August 2017

Birgitta Christina Burckhardt

2

1 reference

23 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21103968

2 September 2024

publication date

1 January 2011

1 reference

full work available at URL

23 August 2017

http://link.springer.com/content/pdf/10.1007/978-3-642-14541-4_2.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Handbook of experimental pharmacology

2 September 2024

published in

1 reference

23 August 2017

issue

201

1 reference

23 August 2017

page(s)

29-104

1 reference

British Journal of Pharmacology

23 August 2017

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2 September 2024

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Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules

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2 September 2024

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2 September 2024

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2 September 2024

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Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells

2 September 2024

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The flounder organic anion transporter fOat has sequence, function, and substrate specificity similarity to both mammalian Oat1 and Oat3.

2 September 2024

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Xenobiotic and endobiotic transporter mRNA expression in the blood-testis barrier

2 September 2024

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Human organic anion transporters mediate the transport of tetracycline

2 September 2024

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Role of human organic anion transporter 4 in the transport of ochratoxin A.

2 September 2024

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https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Genomic structure and in vivo expression of the human organic anion transporter 1 (hOAT1) gene.

2 September 2024

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1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Interaction of the metal chelator 2,3-dimercapto-1-propanesulfonate with the rabbit multispecific organic anion transporter 1 (rbOAT1).

2 September 2024

17

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Expression studies and functional characterization of renal human organic anion transporter 1 isoforms.

2 September 2024

18

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites

2 September 2024

19

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13)

2 September 2024

20

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Human Organic Anion Transporter 3 (hOAT3) can Operate as an Exchanger and Mediate Secretory Urate Flux

2 September 2024

21

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Directing role of organic anion transporters in the excretion of mercapturic acids of alkylated polycyclic aromatic hydrocarbons

2 September 2024

22

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy.

2 September 2024

23

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Activation of protein kinase Czeta increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated transport

2 September 2024

24

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Molecular evidence of organic ion transporters in the rat adrenal cortex with adrenocorticotropin-regulated zonal expression

2 September 2024

25

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

'Benemid,' p-(di-n-propylsulfamyl)-benzoic acid; its renal affinity and its elimination

2 September 2024

26

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3).

2 September 2024

27

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6).

2 September 2024

28

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: a resource for investigations into drug disposition

2 September 2024

29

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

A novel putative transporter maps to the osteosclerosis (oc) mutation and is not expressed in the oc mutant mouse

2 September 2024

30

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Compensation Increase in Organic Anion Excretion in Rats with Acute Biliary Obstruction: Role of the Renal Organic Anion Transporter 1

2 September 2024

31

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3

2 September 2024

32

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Expression of rat renal cortical OAT1 and OAT3 in response to acute biliary obstruction

2 September 2024

33

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Cephalosporin-probenecid drug interactions

2 September 2024

34

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Rat and mouse differences in gender-predominant expression of organic anion transporter (Oat1-3; Slc22a6-8) mRNA levels

2 September 2024

35

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Gender-specific and developmental influences on the expression of rat organic anion transporters

2 September 2024

36

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Endocrine Regulation of Rat Organic Anion Transporters

2 September 2024

37

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Transport of organic anions across the basolateral membrane of proximal tubule cells

2 September 2024

38

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Structure of renal organic anion and cation transporters

2 September 2024

39

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Transport of cimetidine by flounder and human renal organic anion transporter 1.

2 September 2024

40

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta

2 September 2024

41

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Down-regulation of organic anion transporter 2 mRNA expression by nitric oxide in primary cultured rat hepatocytes

2 September 2024

43

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Adaptive responses of renal organic anion transporter 3 (OAT3) during cholestasis

2 September 2024

44

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Drug-metabolizing enzyme and transporter expression in a mouse model of diabetes and obesity.

2 September 2024

45

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Mutational analysis of idiopathic renal hypouricemia in Korea

2 September 2024

46

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats

2 September 2024

47

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats

2 September 2024

48

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein.

2 September 2024

49

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1.

2 September 2024

50

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Organic anion transporter 2 (SLC22A7) is a facilitative transporter of cGMP

2 September 2024

52

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients

2 September 2024

53

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Drug Metabolism and Disposition

2 September 2024

54

24

315

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1996

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Clinical pharmacokinetics of probenecid

2 September 2024

55

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport

2 September 2024

56

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Segment-specific proximal tubule injury in tripterygium glycosides intoxicated rats

2 September 2024

57

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Aristolochic acid nephropathy: a worldwide problem

2 September 2024

58

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Characterization of uremic toxin transport by organic anion transporters in the kidney

2 September 2024

59

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Elimination of organic anions in response to an early stage of renal ischemia-reperfusion in the rat: role of basolateral plasma membrane transporters and cortical renal blood flow

2 September 2024

60

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Expression and function of Oat1 and Oat3 in rat kidney exposed to mercuric chloride.

2 September 2024

61

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

The influence of chronic renal failure on drug metabolism and transport

2 September 2024

62

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

The effect of chronic renal failure on drug metabolism and transport

2 September 2024

63

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Transporters involved in the elimination of drugs in the kidney: organic anion transporters and organic cation transporters

2 September 2024

64

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules

2 September 2024

65

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease

2 September 2024

66

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Roles of organic anion transporters in the progression of chronic renal failure

2 September 2024

67

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Molecular identification of a renal urate anion exchanger that regulates blood urate levels

2 September 2024

68

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors.

2 September 2024

69

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity

2 September 2024

70

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Interactions of human organic anion as well as cation transporters with indoxyl sulfate

2 September 2024

71

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Novel aspects of renal organic anion transporters

2 September 2024

72

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Organic anion and cation transporters occur in pairs of similar and similarly expressed genes

2 September 2024

73

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice.

2 September 2024

74

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics

2 September 2024

75

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3.

2 September 2024

76

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Role of aromatic transmembrane residues of the organic anion transporter, rOAT3, in substrate recognition

2 September 2024

77

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Methotrexate and nonsteroidal antiinflammatory drug interactions

2 September 2024

78

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1).

2 September 2024

79

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate

2 September 2024

81

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Sex differences in the mRNA, protein, and functional expression of organic anion transporter (Oat) 1, Oat3, and organic cation transporter (Oct) 2 in rabbit renal proximal tubules

2 September 2024

82

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Restored expression and activity of organic ion transporters rOAT1, rOAT3 and rOCT2 after hyperuricemia in the rat kidney

2 September 2024

83

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Cloning of the pig renal organic anion transporter 1 (pOAT1).

2 September 2024

84

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Functional expression of pig renal organic anion transporter 3 (pOAT3).

2 September 2024

85

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Torasemide transport by organic anion transporters contributes to hyperuricemia

2 September 2024

86

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https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Human renal organic anion transporter 4 operates as an asymmetric urate transporter

2 September 2024

87

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias

2 September 2024

88

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Interactions of human organic anion transporters with diuretics.

2 September 2024

89

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions

2 September 2024

90

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Contribution of organic anion transporters to the renal uptake of anionic compounds and nucleoside derivatives in rat.

2 September 2024

91

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Molecular physiology of urate transport

2 September 2024

93

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines.

2 September 2024

94

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Transporters and drug therapy: implications for drug disposition and disease

2 September 2024

95

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

COX-2 inhibition attenuates endotoxin-induced downregulation of organic anion transporters in the rat renal cortex

2 September 2024

97

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Influence of probenecid and spironolactone on furosemide kinetics and dynamics in man

2 September 2024

98

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Effects of probenecid on furosemide kinetics and natriuresis in man

2 September 2024

99

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Critical amino acid residues in transmembrane domain 1 of the human organic anion transporter hOAT1.

2 September 2024

100

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Determination of the external loops and the cellular orientation of the N- and the C-termini of the human organic anion transporter hOAT1.

2 September 2024

101

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney

2 September 2024

102

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Function and localization of urate transporter 1 in mouse kidney

2 September 2024

103

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Interaction of imatinib with human organic ion carriers

2 September 2024

104

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Assessment of cisplatin-induced nephrotoxicity by microarray technology

2 September 2024

105

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Urate transport via human PAH transporter hOAT1 and its gene structure

2 September 2024

106

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion

2 September 2024

107

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules

2 September 2024

108

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Drug Metabolism and Disposition

2 September 2024

110

33

1791

T Iwanaga

2005

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Concentration-dependent mode of interaction of angiotensin II receptor blockers with uric acid transporter

2 September 2024

111

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family

2 September 2024

112

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy

2 September 2024

114

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes

2 September 2024

115

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Characterization of ochratoxin A transport by human organic anion transporters

2 September 2024

117

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Involvement of rat organic anion transporter 3 (rOAT3) in cephaloridine-induced nephrotoxicity: in comparison with rOAT1.

2 September 2024

118

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members

2 September 2024

119

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions

2 September 2024

120

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Gender difference in the urinary excretion of organic anions in rats

2 September 2024

121

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Screening of the interaction between xenobiotic transporters and PDZ proteins

2 September 2024

122

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Cell free expression and functional reconstitution of eukaryotic drug transporters

2 September 2024

123

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs

2 September 2024

124

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.

2 September 2024

125

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine.

2 September 2024

126

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier

2 September 2024

127

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation

2 September 2024

128

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation

2 September 2024

129

1 reference

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Up-regulation of organic anion transporter 1 protein is induced by chronic furosemide or hydrochlorothiazide infusion in rat kidney

2 September 2024

130

1 reference

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Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins.

2 September 2024

131

1 reference

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Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

2 September 2024

132

1 reference

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Development and characterization of immobilized human organic anion transporter-based liquid chromatographic stationary phase: hOAT1 and hOAT2.

2 September 2024

133

1 reference

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Differential gene expression of organic anion transporters in male and female rats

2 September 2024

134

1 reference

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Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice

2 September 2024

135

1 reference

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Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3.

2 September 2024

136

1 reference

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Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]).

2 September 2024

137

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

The SLC22 drug transporter family

2 September 2024

138

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia

2 September 2024

140

1 reference

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Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain

2 September 2024

141

1 reference

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Heterologous Expression and Functional Characterization of a Mouse Renal Organic Anion Transporter in Mammalian Cells

2 September 2024

142

1 reference

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Characterization of mouse organic anion transporter 5 as a renal steroid sulfate transporter

2 September 2024

143

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Co-localization and interaction of organic anion transporter 1 with caveolin-2 in rat kidney

2 September 2024

144

1 reference

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Alteration in renal organic anion transporter 1 after ischemia/reperfusion in cadaveric renal allografts

2 September 2024

145

1 reference

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(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (cidofovir): results of a phase I/II study of a novel antiviral nucleotide analogue

2 September 2024

147

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

The presence of xenobiotic transporters in rat placenta.

2 September 2024

148

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Transporters and renal drug elimination

2 September 2024

149

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Molecular cloning and characterization of a human urate transporter (hURAT1) gene promoter

2 September 2024

150

1 reference

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Drug-drug interactions involving membrane transporters in the human kidney

2 September 2024

151

1 reference

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Effects of angiotensin II receptor blockers on renal handling of uric acid in rats

2 September 2024

152

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition

2 September 2024

153

1 reference

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Renal expression of organic anion transporter OAT2 in rats and mice is regulated by sex hormones

2 September 2024

154

1 reference

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Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney

2 September 2024

155

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C

2 September 2024

156

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1alpha.

2 September 2024

157

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Renal and hepatic transporter expression in type 2 diabetic rats

2 September 2024

158

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Involvement of rat and human organic anion transporter 3 in the renal tubular secretion of topotecan [(S)-9-dimethylaminomethyl-10-hydroxy-camptothecin hydrochloride].

2 September 2024

159

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Downregulation of organic anion transporters in rat kidney under ischemia/reperfusion-induced acute [corrected] renal failure

2 September 2024

160

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Role of organic anion transporters in the pharmacokinetics of zonampanel, an alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, in rats

2 September 2024

161

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins

2 September 2024

162

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Impact of drug transporter studies on drug discovery and development

2 September 2024

163

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa

2 September 2024

164

1 reference

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Kidney-specific expression of a novel mouse organic cation transporter-like protein

2 September 2024

165

1 reference

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Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells

2 September 2024

166

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Organic anion transporter 3 is involved in the brain-to-blood efflux transport of thiopurine nucleobase analogs

2 September 2024

167

1 reference

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Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A).

2 September 2024

170

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake

2 September 2024

171

1 reference

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Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus

2 September 2024

173

1 reference

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Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans

2 September 2024

174

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Developmental changes in multispecific organic anion transporter 1 expression in the rat kidney.

2 September 2024

175

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Organic anion transporter OAT1 is involved in renal handling of citrulline

2 September 2024

176

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Down-regulation of intestinal drug transporters in chronic renal failure in rats

2 September 2024

177

1 reference

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Role of mouse organic anion transporter 3 (mOat3) as a basolateral prostaglandin E2 transport pathway

2 September 2024

178

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Tissue-specific mRNA expression profiles of human ATP-binding cassette and solute carrier transporter superfamilies

2 September 2024

179

1 reference

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Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3 and ORCTL4, bearing homology to organic-cation transporters

2 September 2024

180

1 reference

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Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

2 September 2024

181

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Quantitative evaluation of the drug-drug interactions between methotrexate and nonsteroidal anti-inflammatory drugs in the renal uptake process based on the contribution of organic anion transporters and reduced folate carrier

2 September 2024

182

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Characterization of the uptake of organic anion transporter (OAT) 1 and OAT3 substrates by human kidney slices

2 September 2024

183

1 reference

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Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices

2 September 2024

184

1 reference

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Elevated uric acid increases the risk for kidney disease

2 September 2024

185

1 reference

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Human organic anion transporter 3 gene is regulated constitutively and inducibly via a cAMP-response element

2 September 2024

186

1 reference

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Hepatocyte nuclear factor-4{alpha} regulates the human organic anion transporter 1 gene in the kidney

2 September 2024

187

1 reference

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Analysis of regulatory polymorphisms in organic ion transporter genes (SLC22A) in the kidney.

2 September 2024

188

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain

2 September 2024

189

1 reference

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Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier

2 September 2024

190

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

The effect of probenecid on the renal tubular excretion of benzylpenicillin

2 September 2024

191

1 reference

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Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct

2 September 2024

192

1 reference

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A three-dimensional model of human organic anion transporter 1: aromatic amino acids required for substrate transport

2 September 2024

193

1 reference

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Ochratoxin A: An overview on toxicity and carcinogenicity in animals and humans

2 September 2024

194

1 reference

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Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1.

2 September 2024

195

1 reference

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The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4 alpha and suppressed by bile acids.

2 September 2024

196

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Human vascular smooth muscle cells express a urate transporter

2 September 2024

197

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Mechanism of organic anion transport across the apical membrane of choroid plexus

2 September 2024

198

1 reference

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Renal elimination of a novel and potent alphavbeta3 integrin antagonist in animals

2 September 2024

199

1 reference

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Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3)

2 September 2024

200

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Cloning of a human renal p-aminohippurate transporter, hROAT1

2 September 2024

201

1 reference

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Organic anion transporters of the SLC22 family: biopharmaceutical, physiological, and pathological roles

2 September 2024

202

1 reference

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The chloride dependence of the human organic anion transporter 1 (hOAT1) is blunted by mutation of a single amino acid

2 September 2024

203

1 reference

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Pathophysiological regulation of renal SLC22A organic ion transporters in acute kidney injury: pharmacological and toxicological implications

2 September 2024

204

1 reference

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Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 alpha/beta

2 September 2024

205

1 reference

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Expression levels of renal organic anion transporters (OATs) and their correlation with anionic drug excretion in patients with renal diseases

2 September 2024

206

1 reference

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Involvement of uric acid transporters in alteration of serum uric acid level by angiotensin II receptor blockers

2 September 2024

207

1 reference

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Short-term regulation of basolateral organic anion uptake in proximal tubular OK cells: EGF acts via MAPK, PLA(2), and COX1.

2 September 2024

208

1 reference

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Short-term regulation of basolateral organic anion uptake in proximal tubular opossum kidney cells: prostaglandin E2 acts via receptor-mediated activation of protein kinase A.

2 September 2024

209

1 reference

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Action of EGF and PGE2 on basolateral organic anion uptake in rabbit proximal renal tubules and hOAT1 expressed in human kidney epithelial cells

2 September 2024

210

1 reference

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Prostaglandin E2 inhibits its own renal transport by downregulation of organic anion transporters rOAT1 and rOAT3.

2 September 2024

211

1 reference

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Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20)

2 September 2024

212

1 reference

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Downregulation of organic anion transporters OAT1 and OAT3 correlates with impaired secretion of para-aminohippurate after ischemic acute renal failure in rats.

2 September 2024

213

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome

2 September 2024

214

1 reference

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Molecular cloning and characterization of two novel transport proteins from rat kidney

2 September 2024

215

1 reference

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Expression cloning and characterization of a novel multispecific organic anion transporter

2 September 2024

216

1 reference

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Identification of multispecific organic anion transporter 2 expressed predominantly in the liver

2 September 2024

217

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

The multispecific organic anion transporter (OAT) family.

2 September 2024

218

1 reference

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The instructive role of metanephric mesenchyme in ureteric bud patterning, sculpting, and maturation and its potential ability to buffer ureteric bud branching defects

2 September 2024

219

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Effect of methotrexate treatment on expression levels of multidrug resistance protein 2, breast cancer resistance protein and organic anion transporters Oat1, Oat2 and Oat3 in rats

2 September 2024

220

1 reference

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Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate

2 September 2024

222

1 reference

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Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs

2 September 2024

223

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Acute regulation of OAT3-mediated estrone sulfate transport in isolated rabbit renal proximal tubules

2 September 2024

225

1 reference

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Involvement of tyrosine kinase and PI3K in the regulation of OAT3-mediated estrone sulfate transport in isolated rabbit renal proximal tubules

2 September 2024

226

1 reference

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Transport of the natural sweetener stevioside and its aglycone steviol by human organic anion transporter (hOAT1; SLC22A6) and hOAT3 (SLC22A8).

2 September 2024

227

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Interactions of stevioside and steviol with renal organic anion transporters in S2 cells and mouse renal cortical slices

2 September 2024

228

1 reference

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Physiology, structure, and regulation of the cloned organic anion transporters

2 September 2024

229

1 reference

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Structure-affinity relationship in the interactions of human organic anion transporter 1 with caffeine, theophylline, theobromine and their metabolites

2 September 2024

230

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Isolation of a family of organic anion transporters from human liver and kidney

2 September 2024

232

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Organic anion transporter (Slc22a) family members as mediators of toxicity

2 September 2024

233

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Expression cloning and characterization of ROAT1. The basolateral organic anion transporter in rat kidney

2 September 2024

234

1 reference

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Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

2 September 2024

235

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient

2 September 2024

236

1 reference

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Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models

2 September 2024

237

1 reference

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A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters

2 September 2024

238

1 reference

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Molecular cloning and functional analyses of OAT1 and OAT3 from cynomolgus monkey kidney

2 September 2024

239

1 reference

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Is the monkey an appropriate animal model to examine drug-drug interactions involving renal clearance? Effect of probenecid on the renal elimination of H2 receptor antagonists

2 September 2024

240

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid

2 September 2024

241

1 reference

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Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity

2 September 2024

242

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Hydrogen peroxide downregulates human organic anion transporters in the basolateral membrane of the proximal tubule

2 September 2024

243

1 reference

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Regulation by protein kinase C of organic anion transport driven by rat organic anion transporter 3 (rOAT3)

2 September 2024

244

1 reference

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Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters

2 September 2024

245

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Interaction of human organic anion transporters with various cephalosporin antibiotics

2 September 2024

246

1 reference

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Human organic anion transporters and human organic cation transporters mediate renal antiviral transport

2 September 2024

247

1 reference

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Characterization of methotrexate transport and its drug interactions with human organic anion transporters

2 September 2024

248

1 reference

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Evidence for a role of human organic anion transporters in the muscular side effects of HMG-CoA reductase inhibitors

2 September 2024

249

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Role of glycosylation in the organic anion transporter OAT1

2 September 2024

250

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Modulatory effects of hormones, drugs, and toxic events on renal organic anion transport

2 September 2024

251

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen

2 September 2024

252

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Renal elimination of organic anions in cholestasis

2 September 2024

254

1 reference

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Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination

2 September 2024

255

1 reference

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Human organic anion transporter hOAT3 is a potent transporter of cephalosporin antibiotics, in comparison with hOAT1.

2 September 2024

258

1 reference

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Cl- -dependent upregulation of human organic anion transporters: different effects on transport kinetics between hOAT1 and hOAT3.

2 September 2024

259

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Characterization and identification of steroid sulfate transporters of human placenta

2 September 2024

260

1 reference

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Functional differences in steroid sulfate uptake of organic anion transporter 4 (OAT4) and organic anion transporting polypeptide 2B1 (OATP2B1) in human placenta

2 September 2024

261

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Gender differences in expression of organic cation transporter OCT2 in rat kidney

2 September 2024

262

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Functional genomics of membrane transporters in human populations

2 September 2024

263

1 reference

https://api.crossref.org/works/10.1007/978-3-642-14541-4_2

Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney

2 September 2024

264

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Inhibitory effect of anti-diabetic agents on rat organic anion transporter rOAT1.

2 September 2024

265

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Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter

2 September 2024

267

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Methotrexate-loxoprofen interaction: involvement of human organic anion transporters hOAT1 and hOAT3.

2 September 2024

268

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Renal transport of adefovir, cidofovir, and tenofovir by SLC22A family members (hOAT1, hOAT3, and hOCT2).

2 September 2024

269

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Interaction and transport characteristics of mycophenolic acid and its glucuronide via human organic anion transporters hOAT1 and hOAT3

2 September 2024

270

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Organic anion transporter 3 contributes to the regulation of blood pressure

2 September 2024

271

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Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics.

2 September 2024

272

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Molecular pharmacology of renal organic anion transporters

2 September 2024

273

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Drug uptake systems in liver and kidney

2 September 2024

274

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Review on uremic toxins: classification, concentration, and interindividual variability

2 September 2024

275

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Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G

2 September 2024

276

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Impaired clearance of methotrexate in organic anion transporter 3 (Slc22a8) knockout mice: a gender specific impact of reduced folates

2 September 2024

277

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Organic anion transporter 3 (oat3/slc22a8) interacts with carboxyfluoroquinolones, and deletion increases systemic exposure to ciprofloxacin

2 September 2024

278

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Organic anion transporters: discovery, pharmacology, regulation and roles in pathophysiology.

2 September 2024

279

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Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction

2 September 2024

280

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Time course of organic anion excretion in rats with bilateral ureteral obstruction: role of organic anion transporters (Oat1 and Oat3)

2 September 2024

281

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The contribution of organic anion transporters OAT1 and OAT3 to the renal uptake of rosuvastatin

2 September 2024

284

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Expression cloning and characterization of a renal organic anion transporter from winter flounder

2 September 2024

285

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Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization

2 September 2024

286

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Mycophenolic acid (MPA) and its glucuronide metabolites interact with transport systems responsible for excretion of organic anions in the basolateral membrane of the human kidney

2 September 2024

287

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Ontogeny of expression of organic anion transporters 1 and 3 in ovine fetal and neonatal kidney

2 September 2024

288

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Molecular and cellular physiology of renal organic cation and anion transport

2 September 2024

289

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Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)].

2 September 2024

290

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Functional role of the C terminus of human organic anion transporter hOAT1

2 September 2024

292

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Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor

2 September 2024

293

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Inhibitory effects of angiotensin II receptor antagonists and leukotriene receptor antagonists on the transport of human organic anion transporter 4.

2 September 2024

294

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Functional and immunochemical characterization of a novel organic anion transporter Oat8 (Slc22a9) in rat renal collecting duct

2 September 2024

295

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Regulation of mOAT-mediated organic anion transport by okadaic acid and protein kinase C in LLC-PK(1) cells

2 September 2024

296

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Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney

2 September 2024

297

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Renal organic anion transporter-mediated drug-drug interaction between gemcabene and quinapril

2 September 2024

298

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Transport of N-acetylcysteine s-conjugates of methylmercury in Madin-Darby canine kidney cells stably transfected with human isoform of organic anion transporter 1.

2 September 2024

299

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Relative contribution of OAT and OCT transporters to organic electrolyte transport in rabbit proximal tubule

2 September 2024

300

1 reference

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Organic anion transporter OAT1 undergoes constitutive and protein kinase C-regulated trafficking through a dynamin- and clathrin-dependent pathway

2 September 2024

301

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Mutational analysis of histidine residues in human organic anion transporter 4 (hOAT4)

2 September 2024

302

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The role of glycine residues in the function of human organic anion transporter 4

2 September 2024

303

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The role of N-linked glycosylation in protein folding, membrane targeting, and substrate binding of human organic anion transporter hOAT4.

2 September 2024

304

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Functional characterization of a human organic anion transporter hOAT4 in placental BeWo cells

2 September 2024

305

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Regulation of human organic anion transporter 4 by progesterone and protein kinase C in human placental BeWo cells

2 September 2024

306

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Comparison of the interaction of human organic anion transporter hOAT4 with PDZ proteins between kidney cells and placental cells

2 September 2024

307

1 reference

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Low doses of ochratoxin A upregulate the protein expression of organic anion transporters Oat1, Oat2, Oat3 and Oat5 in rat kidney cortex

2 September 2024

308

1 reference

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2 September 2024

Identifiers

1 reference

23 August 2017

1 reference