(Q37813401)

23 August 2017

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title

T-cell alloimmunity and chronic allograft dysfunction (English)

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23 August 2017

1

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Behdad Afzali

2

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author name string

Kerem Atalar

3

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23 August 2017

Giovanna Lombardi

4

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23 August 2017

Robert I Lechler

5

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23 August 2017

publication date

1 December 2010

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Kidney International. Supplement

23 August 2017

published in

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23 August 2017

issue

119

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23 August 2017

page(s)

S2-12

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Molecular mechanisms of renal allograft fibrosis

23 August 2017

cites work

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Chronic allograft nephropathy

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Pathogenesis of chronic allograft rejection

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7 January 2021

The aetiology and pathogenesis of chronic allograft nephropathy

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7 January 2021

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MHC and MHC-Like Molecules: Structural Perspectives on the Design of Molecular Vaccines

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7 January 2021

The molecular basis of allorecognition

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7 January 2021

Weaning of immunosuppression in living donor liver transplant recipients

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7 January 2021

An appraisal of tolerance in liver transplantation

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7 January 2021

Complete weaning off immunosuppression in HCV liver transplant recipients is feasible and favourably impacts on the progression of disease recurrence

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https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Induction of immunological tolerance by porcine liver allografts

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https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Presentation and recognition of major and minor histocompatibility antigens

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https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

The structural basis of T-cell allorecognition

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells

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https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

A novel pathway of alloantigen presentation by dendritic cells

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https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

The homograft reaction

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Activation of cytotoxic T cells by nonstimulating tumor cells and spleen cell factor(s)

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Activation of Transplant Immunity: Effect of Donor Leukocytes on Thyroid Allograft Rejection

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https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Successful allotransplantation of mouse pancreatic islets to nonimmunosuppressed recipients

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

CD4 T cell-mediated cardiac allograft rejection requires donor but not host MHC class II.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

The role of the allograft in the induction of donor-specific T cell hyporesponsiveness.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Are primary alloresponses truly primary?

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Allorecognition of HLA-DR and -DQ transfectants by human CD45RA and CD45R0 CD4 T cells: repertoire analysis and activation requirements

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

T cell receptor expression and receptor-mediated induction of clonal growth in the developing mouse thymus. High surface beta-chain density is a requirement for functional maturity

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens?

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Inhibition of allorecognition by an H-2Kb-derived peptide is evidence for a T-cell binding region on a major histocompatibility complex molecule

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

The specificity of alloreactive T cells is determined by MHC polymorphisms which contact the T cell receptor and which influence peptide binding

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Peptide-independent recognition by alloreactive cytotoxic T lymphocytes (CTL).

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Structural studies on the alphabeta T-cell receptor

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Structural determinants of T-cell receptor bias in immunity

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Peptide-mediated modulation of T-cell allorecognition

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

On the nature of peptides involved in T cell alloreactivity

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Overlap in the repertoires of peptides bound in vivo by a group of related class I HLA-B allotypes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Assessment of the contribution that direct allorecognition makes to the progression of chronic cardiac transplant rejection in humans

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Immunogenicity of retransplanted rat kidney allografts. Effect of inducing chimerism in the first recipient and quantitative studies on immunosuppression of the second recipient

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Corecognition of HLA-A1 and HLA-DPw3 by a human CD4+ alloreactive T lymphocyte clone

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

T cells sensitized to synthetic HLA-DR3 peptide give evidence of continuous presentation of denatured HLA-DR3 molecules by HLA-DP.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

A subpopulation of mouse cytotoxic T lymphocytes recognizes allogeneic H-2 class I antigens in the context of other H-2 class I molecules

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Cross-primed CD8(+) T cells mediate graft rejection via a distinct effector pathway

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

CD8 T cells specific for a donor-derived, self-restricted transplant antigen are nonpathogenic bystanders after vascularized heart transplantation in mice.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Two levels of help for B cell alloantibody production

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Pathways of helper CD4 T cell allorecognition in generating alloantibody and CD8 T cell alloimmunity

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

B cell-mediated antigen presentation is required for the pathogenesis of acute cardiac allograft rejection

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Acquisition of HLA-DR and costimulatory molecules by T cells from allogeneic antigen presenting cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Intercellular transfer of MHC and immunological molecules: molecular mechanisms and biological significance

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Embryonic thymic epithelium naturally devoid of APCs is acutely rejected in the absence of indirect recognition.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Rejection of mouse cardiac allografts by costimulation in trans

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Migration and maturation of Langerhans cells in skin transplants and explants

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

New TCR transgenic model for tracking allospecific CD4 T-cell activation and tolerance in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Alloreactive CD4 T cell activation in vivo: an autonomous function of the indirect pathway of alloantigen presentation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Antigen presentation by keratinocytes induces tolerance in human T cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Antigen presentation by interferon-γ-treated thyroid follicular cells inhibits interleukin-2 (IL-2) and supports IL-4 production by B7-dependent human T cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Major histocompatibility complex class II-expressing endothelial cells induce allospecific nonresponsiveness in naive T cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

A T cell clone expresses two T cell receptor alpha genes but uses one alpha beta heterodimer for allorecognition and self MHC-restricted antigen recognition.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Cognate recognition of the endothelium induces HY-specific CD8+ T-lymphocyte transendothelial migration (diapedesis) in vivo

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Neointimal and tubulointerstitial infiltration by recipient mesenchymal cells in chronic renal-allograft rejection.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

The replacement of graft endothelium by recipient-type cells conditions allograft rejection mediated by indirect pathway CD4+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Relative roles of Th1 and Th17 effector cells in allograft rejection.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Th17 cell differentiation: the long and winding road

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Role of IL-4 and Th2 responses in allograft rejection and tolerance

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

IL-17 family cytokines and the expanding diversity of effector T cell lineages

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

A novel transcription factor, T-bet, directs Th1 lineage commitment

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Cytokines and the Th1/Th2 paradigm in transplantation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Neutrophils mediate parenchymal tissue necrosis and accelerate the rejection of complete major histocompatibility complex-disparate cardiac allografts in the absence of interferon-gamma

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Early immunological monitoring after pediatric liver transplantation: cytokine immune deviation and graft acceptance in 40 recipients

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Evidence for IFN-gamma up- and IL-4 downregulation late post-transplant in patients with good kidney graft outcome

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Functionally significant renal allograft rejection is defined by transcriptional criteria

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Evidence for the early involvement of interleukin 17 in human and experimental renal allograft rejection

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Regulatory T cells - a brief history and perspective

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked: forkhead box protein 3 mutations and lack of regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

IPEX, FOXP3 and regulatory T-cells: a model for autoimmunity.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. III. Further characterization of the CD4+ suppressor cell and its mechanisms of action

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Identification of regulatory T cells in tolerated allografts

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Induction of operational tolerance and generation of regulatory cells after intratracheal delivery of alloantigen combined with nondepleting anti-CD4 monoclonal antibody

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Influence of direct and indirect allorecognition pathways on CD4+CD25+ regulatory T-cell function in transplantation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Modified dendritic cells coexpressing self and allogeneic major histocompatability complex molecules: an efficient way to induce indirect pathway regulation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Significant frequencies of T cells with indirect anti-donor specificity in heart graft recipients with chronic rejection

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

CD4+CD25+ regulatory T cells do not significantly contribute to direct pathway hyporesponsiveness in stable renal transplant patients

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Regulatory CD25+ T cells in human kidney transplant recipients

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Relative contribution of direct and indirect allorecognition in developing tolerance after liver transplantation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

FoxP3+ regulatory T cells suppress early stages of granuloma formation but have little impact on sarcoidosis lesions

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Regulatory T cells in kidney allograft infiltrates correlate with initial inflammation and graft function

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

FOXP3-enriched infiltrates associated with better outcome in renal allografts with inflamed fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Abrogation of antibody-mediated allograft rejection by regulatory CD4 T cells with indirect allospecificity

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Mixed allogeneic chimerism as an approach to transplantation tolerance

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

HLA-mismatched renal transplantation without maintenance immunosuppression

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Plasmacytoid dendritic cells in immunity

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Antigen-presentation properties of plasmacytoid dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Plasmacytoid dendritic cells in autoimmune diabetes - potential tools for immunotherapy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Targeting MHC class I monomers to dendritic cells inhibits the indirect pathway of allorecognition and the production of IgG alloantibodies leading to long-term allograft survival.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

B-cell-depleting induction therapy and acute cellular rejection

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

A randomized, doubleblind, placebo-controlled, study of single-dose rituximab as induction in renal transplantation.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2010.416

7 January 2021

Identifiers

DOI

10.1038/KI.2010.416

1 reference

23 August 2017

1 reference