(Q37816952)

23 August 2017

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title

The bone-cartilage unit in osteoarthritis (English)

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23 August 2017

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Rik J Lories

1

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23 August 2017

Frank P Luyten

series ordinal

2

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23 August 2017

language of work or name

English

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publication date

7 December 2010

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Nature Reviews Rheumatology

23 August 2017

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23 August 2017

7

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23 August 2017

1

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23 August 2017

43-49

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https://scigraph.springernature.com/pub.10.1038/nrrheum.2010.197

23 August 2017

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cites work

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Control of Dkk-1 ameliorates chondrocyte apoptosis, cartilage destruction, and subchondral bone deterioration in osteoarthritic knees.

21 January 2018

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ERK-1/2 and p38 in the regulation of hypertrophic changes of normal articular cartilage chondrocytes induced by osteoarthritic subchondral osteoblasts.

21 January 2018

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21 January 2018

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31 March 2020

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New horizons and perspectives in the treatment of osteoarthritis

31 March 2020

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The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis results of two metaanalyses

31 March 2020

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Lessons from genetic forms of osteoarthritis for the pathogenesis of the disease

31 March 2020

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A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis

31 March 2020

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The contribution of genes to osteoarthritis

31 March 2020

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The clinical relevance of genetic susceptibility to osteoarthritis

31 March 2020

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An SNP in the 5'-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage

31 March 2020

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Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand

31 March 2020

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Relationship between joint shape and the development of osteoarthritis

31 March 2020

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Yet more evidence that osteoarthritis is not a cartilage disease

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis

31 March 2020

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Contemporary concepts of inflammation, damage and repair in rheumatic diseases.

31 March 2020

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Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis

31 March 2020

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On new bone formation in the pre-osteoarthritic joint

31 March 2020

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A decreased subchondral trabecular bone tissue elastic modulus is associated with pre-arthritic cartilage damage.

31 March 2020

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Finite element studies of some juxtarticular stress changes due to localized subchondral stiffening.

31 March 2020

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A type I collagen defect leads to rapidly progressive osteoarthritis in a mouse model

31 March 2020

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Role of subchondral bone in osteoarthritis development: a comparative study of two strains of guinea pigs with and without spontaneously occurring osteoarthritis

31 March 2020

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GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes

31 March 2020

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Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss: the MOST Study. A longitudinal multicentre study of knee osteoarthritis

31 March 2020

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Pre-radiographic MRI findings are associated with onset of knee symptoms: the most study

31 March 2020

1 reference

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Correlation between bone lesion changes and cartilage volume loss in patients with osteoarthritis of the knee as assessed by quantitative magnetic resonance imaging over a 24-month period

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Cartilage loss occurs in the same subregions as subchondral bone attrition: a within-knee subregion-matched approach from the Multicenter Osteoarthritis Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Subchondral bone marrow lesions are highly associated with, and predict subchondral bone attrition longitudinally: the MOST study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Subchondral bone attrition may be a reflection of compartment-specific mechanical load: the MOST Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Subchondral pathways to the superior surface of the human talus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

The normal human chondro-osseous junctional region: evidence for contact of uncalcified cartilage with subchondral bone and marrow spaces

31 March 2020

1 reference

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Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis.

31 March 2020

1 reference

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The basic science of the subchondral bone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

In situ measurement of transport between subchondral bone and articular cartilage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Increased hydraulic conductance of human articular cartilage and subchondral bone plate with progression of osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Wnt signaling and osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Bone morphogenetic proteins and articular cartilage: To serve and protect or a wolf in sheep clothing's?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Inhibition of beta-catenin signaling in articular chondrocytes results in articular cartilage destruction

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Articular cartilage and biomechanical properties of the long bones in Frzb-knockout mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Bone morphogenetic protein signaling and arthritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Alteration of cartilage metabolism by cells from osteoarthritic bone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: possible role in subchondral bone sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Can altered production of interleukin-1beta, interleukin-6, transforming growth factor-beta and prostaglandin E(2) by isolated human subchondral osteoblasts identify two subgroups of osteoarthritic patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Phenotypic characterization of osteoblasts from the sclerotic zones of osteoarthritic subchondral bone.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Osteoblasts from the sclerotic subchondral bone downregulate aggrecan but upregulate metalloproteinases expression by chondrocytes. This effect is mimicked by interleukin-6, -1beta and oncostatin M pre-treated non-sclerotic osteoblasts.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Subchondral bone osteoblasts induce phenotypic changes in human osteoarthritic chondrocytes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Applying an excessive mechanical stress alters the effect of subchondral osteoblasts on chondrocytes in a co-culture system.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Osteoarthritic cartilage chondrocytes alter subchondral bone osteoblast differentiation via MAPK signalling pathway involving ERK1/2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Protease-activated receptor 2: a novel pathogenic pathway in a murine model of osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.197

Importance of subchondral bone to articular cartilage in health and disease

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21135881

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of subchondral bone in the initiation and progression of cartilage damage.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21135881

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRRHEUM.2010.197

1 reference

Dimensions Publication ID

23 August 2017

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1 reference