(Q37824159)

23 August 2017

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title

Measuring low levels of protein aggregation by sedimentation velocity (English)

1 reference

23 August 2017

1 reference

John P Gabrielson

1

1 reference

PubMed ID

21187149

23 August 2017

Kelly K Arthur

series ordinal

2

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23 August 2017

25 December 2010

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23 August 2017

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23 August 2017

54

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23 August 2017

83-91

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23 August 2017

1

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Modern applications of analytical ultracentrifugation

23 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Role of analytical ultracentrifugation in assessing the aggregation of protein biopharmaceuticals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Effects of protein aggregates: an immunologic perspective

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Structure-immunogenicity relationships of therapeutic proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Quantitation of aggregate levels in a recombinant humanized monoclonal antibody formulation by size-exclusion chromatography, asymmetrical flow field flow fractionation, and sedimentation velocity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Is any measurement method optimal for all aggregate sizes and types?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Detection of protein aggregates by sedimentation velocity analytical ultracentrifugation (SV-AUC): sources of variability and their relative importance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

A bayesian approach for quantifying trace amounts of antibody aggregates by sedimentation velocity analytical ultracentrifugation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Common excipients impair detection of protein aggregates during sedimentation velocity analytical ultracentrifugation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Precision of protein aggregation measurements by sedimentation velocity analytical ultracentrifugation in biopharmaceutical applications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

A critical review of analytical ultracentrifugation and field flow fractionation methods for measuring protein aggregation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Quantitation of aggregates in therapeutic proteins using sedimentation velocity analytical ultracentrifugation: practical considerations that affect precision and accuracy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

A model for sedimentation in inhomogeneous media. I. Dynamic density gradients from sedimenting co-solutes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

A model for sedimentation in inhomogeneous media. II. Compressibility of aqueous and organic solvents.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Size-distribution analysis of proteins by analytical ultracentrifugation: strategies and application to model systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Determination of molecular parameters by fitting sedimentation data to finite-element solutions of the Lamm equation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Boundary analysis in sedimentation transport experiments: a procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

A method for directly fitting the time derivative of sedimentation velocity data and an alternative algorithm for calculating sedimentation coefficient distribution functions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Using prior knowledge in the determination of macromolecular size-distributions by analytical ultracentrifugation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

Calculating sedimentation coefficient distributions by direct modeling of sedimentation velocity concentration profiles.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

10.1016/J.YMETH.2010.12.030

7 January 2021

Identifiers

DOI

1 reference

23 August 2017

1 reference

PubMed ID

21187149