(Q37826382)

23 August 2017

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title

The molecular basis of iron overload disorders and iron-linked anemias (English)

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23 August 2017

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Jerry Kaplan

1

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PubMed ID

21210258

23 August 2017

Diane M Ward

series ordinal

2

1 reference

PubMed ID

21210258

23 August 2017

Ivana De Domenico

series ordinal

3

1 reference

23 August 2017

7 January 2011

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International Journal of Hematology

23 August 2017

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23 August 2017

93

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23 August 2017

1

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23 August 2017

14-20

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https://scigraph.springernature.com/pub.10.1007/s12185-010-0760-0

23 August 2017

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cites work

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

RETRACTED: The hepcidin-binding site on ferroportin is evolutionarily conserved

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Severe iron deficiency anemia in transgenic mice expressing liver hepcidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

The molecular mechanism of hepcidin-mediated ferroportin down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

The molecular basis of ferroportin-linked hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Resistance to hepcidin is conferred by hemochromatosis-associated mutations of ferroportin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Functional consequences of ferroportin 1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Impaired iron transport activity of ferroportin 1 in hereditary iron overload

21 January 2018

1 reference

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Zebrafish as a model for defining the functional impact of mammalian ferroportin mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Evidence for the multimeric structure of ferroportin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

The molecular basis of hepcidin-resistant hereditary hemochromatosis

21 January 2018

1 reference

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Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

21 January 2018

1 reference

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BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

21 January 2018

1 reference

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The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

21 January 2018

The ferroportin disease

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Human mutation D157G in ferroportin leads to hepcidin-independent binding of Jak2 and ferroportin down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Functional analysis and theoretical modeling of ferroportin reveals clustering of mutations according to phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Toll-like receptors mediate induction of hepcidin in mice infected with Borrelia burgdorferi

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Regulation of hepcidin transcription by interleukin-1 and interleukin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

The serine protease TMPRSS6 is required to sense iron deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Role of ceruloplasmin in macrophage iron efflux during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Ferroxidase activity is required for the stability of cell surface ferroportin in cells expressing GPI-ceruloplasmin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-010-0760-0

Function and regulation of transferrin and ferritin.

21 January 2018

1 reference

12 December 2020

Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter

1 reference

12 December 2020

1 reference

12 December 2020

Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux

1 reference

12 December 2020

Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene

1 reference

12 December 2020

Iron-Induced Expression of Bone Morphogenic Protein 6 in Intestinal Cells Is the Main Regulator of Hepatic Hepcidin Expression In Vivo

1 reference

12 December 2020

10.1007/S12185-010-0760-0

Identifiers

DOI

1 reference

23 August 2017

1 reference

PubMed ID

21210258