(Q37832457)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21268062%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

review article

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title

Key roles of histone methyltransferase and demethylase in leukemogenesis (English)

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20 January 2020

1

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20 January 2020

author name string

Mineo Kurokawa

series ordinal

2

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20 January 2020

publication date

1 February 2011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21268062%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cellular Biochemistry

20 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21268062%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

112

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20 January 2020

issue

2

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20 January 2020

page(s)

415-424

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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

20 January 2020

cites work

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BMI-1 expression is enhanced through transcriptional and posttranscriptional regulation during the progression of chronic myeloid leukemia

21 January 2018

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The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)

21 January 2018

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The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation

21 January 2018

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Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

21 January 2018

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Recruitment of the histone methyltransferase SUV39H1 and its role in the oncogenic properties of the leukemia-associated PML-retinoic acid receptor fusion protein

21 January 2018

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EVI1 recruits the histone methyltransferase SUV39H1 for transcription repression

21 January 2018

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Expression of a CALM-AF10 fusion gene leads to Hoxa cluster overexpression and acute leukemia in transgenic mice

21 January 2018

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SUV39H1 interacts with AML1 and abrogates AML1 transactivity. AML1 is methylated in vivo

21 January 2018

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Protein arginine-methyltransferase-dependent oncogenesis

21 January 2018

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Identification of two critically deleted regions within chromosome segment 7q35-q36 in EVI1 deregulated myeloid leukemia cell lines

21 January 2018

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Mutation in TET2 in myeloid cancers

21 January 2018

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Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation

21 January 2018

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MLL5, a homolog of Drosophila trithorax located within a segment of chromosome band 7q22 implicated in myeloid leukemia

21 January 2018

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Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

21 January 2018

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Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation.

21 January 2018

1 reference

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

21 January 2018

1 reference

The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3

21 January 2018

1 reference

Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia.

21 January 2018

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Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells.

21 January 2018

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Gene expression profiling of Polycomb, Hox and Meis genes in patients with acute myeloid leukaemia.

21 January 2018

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The polycomb protein MPc3 interacts with AF9, an MLL fusion partner in t(9;11)(p22;q23) acute leukemias

21 January 2018

1 reference

A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31.

21 January 2018

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LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

21 January 2018

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The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling

21 January 2018

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JmjC-domain-containing proteins and histone demethylation

21 January 2018

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H3K79 methylation profiles define murine and human MLL-AF4 leukemias

21 January 2018

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Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase

21 January 2018

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The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3

21 January 2018

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Haploinsufficiency of NSD1 causes Sotos syndrome

21 January 2018

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Control of developmental regulators by Polycomb in human embryonic stem cells

21 January 2018

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Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

21 January 2018

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Imprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignancies

21 January 2018

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The polycomb group BMI1 gene is a molecular marker for predicting prognosis of chronic myeloid leukemia.

21 January 2018

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A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification

21 January 2018

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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

21 January 2018

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Alteration of enhancer of polycomb 1 at 10p11.2 is one of the genetic events leading to development of adult T-cell leukemia/lymphoma

21 January 2018

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Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

21 January 2018

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BMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas

21 January 2018

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hDOT1L links histone methylation to leukemogenesis

21 January 2018

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Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2

21 January 2018

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Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera

21 January 2018

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NSD1 is essential for early post-implantation development and has a catalytically active SET domain

21 January 2018

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Regulation of chromatin structure by site-specific histone H3 methyltransferases

21 January 2018

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RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription.

21 January 2018

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BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells

21 January 2018

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Selective interactions between vertebrate polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins

21 January 2018

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Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells

21 January 2018

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A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a

21 January 2018

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Methylation of histone H4 at arginine 3 occurs in vivo and is mediated by the nuclear receptor coactivator PRMT1

21 January 2018

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Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3

21 January 2018

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Prognostically useful gene-expression profiles in acute myeloid leukemia.

21 January 2018

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BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia

21 January 2018

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Identification of NUP98 abnormalities in acute leukemia: JARID1A (12p13) as a new partner gene

21 January 2018

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Role of the polycomb repressive complex 2 in acute promyelocytic leukemia

21 January 2018

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The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow

21 January 2018

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Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor

21 January 2018

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NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.

21 January 2018

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Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger

21 January 2018

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The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.

21 January 2018

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MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein

21 January 2018

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Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression

21 January 2018

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Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCB.22972

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21268062%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference