(Q37848274)

24 August 2017

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title

The thrombopoietin/MPL pathway in hematopoiesis and leukemogenesis (English)

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24 August 2017

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Fu-Sheng Chou

1

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24 August 2017

James C Mulloy

series ordinal

2

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24 August 2017

publication date

1 June 2011

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Journal of Cellular Biochemistry

24 August 2017

published in

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24 August 2017

volume

112

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24 August 2017

issue

6

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24 August 2017

page(s)

1491-1498

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c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia

24 August 2017

cites work

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The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity

21 January 2018

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Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

21 January 2018

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Circulating thrombopoietin as an in vivo growth factor for blast cells in acute myeloid leukemia

21 January 2018

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The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential

21 January 2018

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Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia

21 January 2018

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Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis

21 January 2018

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Thrombopoietin expands hematopoietic stem cells after transplantation

21 January 2018

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Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.

21 January 2018

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Thrombocytopenia in c-mpl-deficient mice

21 January 2018

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Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation

21 January 2018

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MPLW515L mutation in acute megakaryoblastic leukaemia.

21 January 2018

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AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

21 January 2018

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A prototype nonpeptidyl, hydrazone class, thrombopoietin receptor agonist, SB-559457, is toxic to primary human myeloid leukemia cells.

21 January 2018

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Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

21 January 2018

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Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin.

21 January 2018

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Thrombopoietin stimulates Hoxb4 expression: an explanation for the favorable effects of TPO on hematopoietic stem cells.

21 January 2018

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Thrombopoietin induces HOXA9 nuclear transport in immature hematopoietic cells: potential mechanism by which the hormone favorably affects hematopoietic stem cells

21 January 2018

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Continuous expression of Bcl-xL protein during megakaryopoiesis is post-translationally regulated by thrombopoietin-mediated Akt activation, which prevents the cleavage of Bcl-xL.

21 January 2018

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Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

21 January 2018

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Posttransplant thrombopoiesis predicts survival in patients undergoing autologous hematopoietic progenitor cell transplantation

21 January 2018

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Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

21 January 2018

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The role of apoptosis in the development of AGM hematopoietic stem cells revealed by Bcl-2 overexpression.

21 January 2018

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MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients

21 January 2018

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Dual role of Mpl receptor during the establishment of definitive hematopoiesis.

21 January 2018

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MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia

21 January 2018

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Critical Role of Thrombopoietin in Maintaining Adult Quiescent Hematopoietic Stem Cells

21 January 2018

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Antiapoptotic protein Bcl-x(L) is up-regulated during megakaryocytic differentiation of CD34(+) progenitors but is absent from senescent megakaryocytes.

21 January 2018

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AML1/RUNX1 works as a negative regulator of c-Mpl in hematopoietic stem cells

21 January 2018

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A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors

21 January 2018

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Congenital amegakaryocytic thrombocytopenia-3 novel c-MPL mutations and their phenotypic correlations

21 January 2018

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Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily

21 January 2018

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cMpl ligand is a humoral regulator of megakaryocytopoiesis

21 January 2018

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Balancing dormant and self-renewing hematopoietic stem cells

21 January 2018

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Sustained ex vivo expansion of hematopoietic stem cells mediated by thrombopoietin

21 January 2018

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Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCB.23089

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release_txdnsszahrfjbc22n6bw7a3q2y

24 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/txdnsszahrfjbc22n6bw7a3q2y

mapped directly with Wikidata item

24 November 2022

based on heuristic

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