(Q37851011)

24 August 2017

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title

The cancer stem cell: premises, promises and challenges (English)

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24 August 2017

main subject

neoplastic stem cells

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Hans Clevers

1

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24 August 2017

language of work or name

English

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publication date

1 March 2011

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24 August 2017

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24 August 2017

volume

17

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24 August 2017

issue

3

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24 August 2017

page(s)

313-319

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Models, mechanisms and clinical evidence for cancer dormancy

24 August 2017

cites work

1 reference

Stem cell concepts renew cancer research

21 January 2018

1 reference

Further evidence favoring the concept of the stem cell in ascites tumors of rats

21 January 2018

1 reference

Studies of the dissemination and quantitative transplantation of a lymphocytic leukaemia of CBA mice

21 January 2018

1 reference

The clonal evolution of tumor cell populations

21 January 2018

1 reference

A genetic model for colorectal tumorigenesis

21 January 2018

1 reference

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

21 January 2018

1 reference

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

1 reference

Prospective identification of tumorigenic breast cancer cells

21 January 2018

1 reference

Identification of human brain tumour initiating cells

21 January 2018

1 reference

Phenotypic characterization of human colorectal cancer stem cells

21 January 2018

1 reference

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

1 reference

Identification and expansion of human colon-cancer-initiating cells

21 January 2018

1 reference

The cancer stem cell paradigm: a new understanding of tumor development and treatment

21 January 2018

1 reference

Efficient tumour formation by single human melanoma cells

21 January 2018

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Heterogeneity in cancer: cancer stem cells versus clonal evolution

21 January 2018

1 reference

Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized

21 January 2018

1 reference

A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

21 January 2018

1 reference

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

21 January 2018

1 reference

Species specificity of iron delivery in hybridomas

21 January 2018

1 reference

Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

21 January 2018

1 reference

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

21 January 2018

1 reference

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 January 2018

1 reference

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia

21 January 2018

1 reference

Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors

21 January 2018

1 reference

Identification of tumor-initiating cells in a p53-null mouse model of breast cancer

21 January 2018

1 reference

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

21 January 2018

1 reference

Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia

21 January 2018

1 reference

Epithelial stem cells: turning over new leaves

21 January 2018

1 reference

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

21 January 2018

1 reference

Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas.

21 January 2018

1 reference

CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells

21 January 2018

1 reference

A hierarchy of self-renewing tumor-initiating cell types in glioblastoma

21 January 2018

1 reference

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

21 January 2018

1 reference

Identification of cells initiating human melanomas

21 January 2018

1 reference

The tortoise and the hair: slow-cycling cells in the stem cell race

21 January 2018

1 reference

Targeting leukemic stem cells by breaking their dormancy

21 January 2018

1 reference

Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content

21 January 2018

1 reference

Tumour-initiating cells: challenges and opportunities for anticancer drug discovery

21 January 2018

1 reference

Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

21 January 2018

1 reference

Association of reactive oxygen species levels and radioresistance in cancer stem cells

21 January 2018

1 reference

Targeted CML therapy: controlling drug resistance, seeking cure

21 January 2018

1 reference

Persistence of leukemia-initiating cells in a conditional knockin model of an imatinib-responsive myeloproliferative disorder

21 January 2018

1 reference

Curing metastatic cancer: lessons from testicular germ-cell tumours

21 January 2018

1 reference

Leukemia-initiating cells in human T-lymphoblastic leukemia exhibit glucocorticoid resistance.

21 January 2018

1 reference

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

21 January 2018

1 reference

Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype

21 January 2018

1 reference

Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues.

21 January 2018

1 reference

Genomic Instability and Cancer

21 January 2018

1 reference

Cancer genes and the pathways they control

21 January 2018

1 reference

Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency

21 January 2018

1 reference

The biology of CML blast crisis

21 January 2018

1 reference

21 January 2018

Mutations for the people

1 reference

Cancer genome sequencing: a review

21 January 2018

1 reference

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

21 January 2018

1 reference

Genome remodelling in a basal-like breast cancer metastasis and xenograft

21 January 2018

1 reference

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

21 January 2018

1 reference

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

21 January 2018

1 reference

A Quantitative Assay for the Number of Murine Lymphoma Cells capable of Proliferation in vivo

21 January 2018

1 reference

Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells

21 January 2018

1 reference

Tumors as caricatures of the process of tissue renewal: prospects for therapy by directing differentiation

21 January 2018

1 reference

12 December 2020

Tumor growth need not be driven by rare cancer stem cells

2 references

12 December 2020

7 January 2021

inferred from DOI database lookup

Acute leukemia: is there a relationship between cell growth kinetics and response to chemotherapy?

1 reference

12 December 2020

CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors

1 reference

12 December 2020

MULTIPOTENTIALITY OF SINGLE EMBRYONAL CARCINOMA CELLS

1 reference

12 December 2020

Review of recent studies of cellular proliferation in acute leukemia.

1 reference

12 December 2020

Differentiation of malignant to benign cells

1 reference

12 December 2020

Improved engraftment of human acute myeloid leukemia progenitor cells in beta 2-microglobulin-deficient NOD/SCID mice and in NOD/SCID mice transgenic for human growth factors

1 reference

12 December 2020

Leukemic cell growth in SCID mice as a predictor of relapse in high-risk B-lineage acute lymphoblastic leukemia

1 reference

12 December 2020

A method for locating radioactive elements in tissues by covering histological sections with a photographic emulsion

1 reference

12 December 2020

Treatment of acute leukemia in adults

1 reference

12 December 2020

Renewal of spermatogonia in the rat

1 reference

12 December 2020

Estimation of phases of the life cycle of leukemic cells from labeling in human beings in vivo with tritiated thymidine

1 reference

12 December 2020

Studies of cellular proliferation in human leukemia. 3. Behavior of leukemic cells in three adults with acute leukemia given continuous infusions of 3H-thymidine for 8 or 10 days

1 reference

12 December 2020

Changing concepts of treatment in acute leukemia

1 reference

12 December 2020

Identification of A2B5+CD133- tumor-initiating cells in adult human gliomas

1 reference

12 December 2020

Comment on "Tumor growth need not be driven by rare cancer stem cells".

1 reference

12 December 2020

The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis

1 reference

12 December 2020

Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.

1 reference

12 December 2020

Comment on "Tumor Growth Need Not Be Driven by Rare Cancer Stem Cells"

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.2304

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24 August 2017

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