(Q37851541)

24 August 2017

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title

Genetic, molecular and physiological insights into human obesity (English)

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24 August 2017

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I Sadaf Farooqi

1

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24 August 2017

publication date

1 April 2011

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European Journal of Clinical Investigation

24 August 2017

published in

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24 August 2017

volume

41

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24 August 2017

issue

4

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24 August 2017

page(s)

451-455

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Positional cloning of the mouse obese gene and its human homologue

24 August 2017

cites work

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https://api.crossref.org/works/10.1111%2FJ.1365-2362.2010.02468.X

Role of leptin in the neuroendocrine response to fasting

21 January 2018

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Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

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Congenital leptin deficiency is associated with severe early-onset obesity in humans

21 January 2018

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Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor

21 January 2018

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Effects of recombinant leptin therapy in a child with congenital leptin deficiency.

21 January 2018

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Leptin regulates striatal regions and human eating behavior

21 January 2018

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Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.

21 January 2018

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Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

21 January 2018

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Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.

21 January 2018

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A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance

21 January 2018

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A role for beta-melanocyte-stimulating hormone in human body-weight regulation

21 January 2018

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Mutations in the amino-terminal region of proopiomelanocortin (POMC) in patients with early-onset obesity impair POMC sorting to the regulated secretory pathway

21 January 2018

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Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency

21 January 2018

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Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees.

21 January 2018

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Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

21 January 2018

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The central melanocortin system directly controls peripheral lipid metabolism

21 January 2018

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Obesity due to melanocortin 4 receptor (MC4R) deficiency is associated with increased linear growth and final height, fasting hyperinsulinemia, and incompletely suppressed growth hormone secretion

21 January 2018

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Melanocortin-4 receptor-deficient mice are not hypertensive or salt-sensitive despite obesity, hyperinsulinemia, and hyperleptinemia.

21 January 2018

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Modulation of blood pressure by central melanocortinergic pathways

21 January 2018

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Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene

21 January 2018

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A de novo mutation affecting human TrkB associated with severe obesity and developmental delay

21 January 2018

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Large, rare chromosomal deletions associated with severe early-onset obesity

21 January 2018

1 reference

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Prevalence and functionality of paucimorphic and privateMC4Rmutations in a large, unselected European British population, scanned by meltMADGE

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2010.02468.X

Heterozygosity for aPOMC-Null Mutation and Increased Obesity Risk in Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2010.02468.X

Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2362.2010.02468.X

10.1111/J.1365-2362.2010.02468.X

21 January 2018

Identifiers

DOI

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24 August 2017

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