(Q37853118)

24 August 2017

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title

Heads-up: new roles for the fragile X mental retardation protein in neural stem and progenitor cells (English)

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24 August 2017

Matthew A Callan

1

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24 August 2017

Daniela C Zarnescu

series ordinal

2

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24 August 2017

publication date

31 May 2011

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24 August 2017

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24 August 2017

volume

49

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24 August 2017

issue

6

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24 August 2017

page(s)

424-440

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Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain.

24 August 2017

cites work

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In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog

21 January 2018

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FMR1 protein: conserved RNP family domains and selective RNA binding

21 January 2018

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Establishing embryonic mouse neural stem cell culture using the neurosphere assay.

21 January 2018

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From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome

21 January 2018

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The mystery and magic of glia: a perspective on their roles in health and disease

21 January 2018

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Branchless and Hedgehog operate in a positive feedback loop to regulate the initiation of neuroblast division in the Drosophila larval brain

21 January 2018

1 reference

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

21 January 2018

1 reference

Genetic and systems level analysis of Drosophila sticky/citron kinase and dFmr1 mutants reveals common regulation of genetic networks

21 January 2018

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Therapeutic implications of the mGluR theory of fragile X mental retardation

21 January 2018

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The mGluR theory of fragile X mental retardation

21 January 2018

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Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain development

21 January 2018

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Normal Neurogenesis but Abnormal Gene Expression in Human Fragile X Cortical Progenitor Cells.

21 January 2018

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Identification of Drosophila type II neuroblast lineages containing transit amplifying ganglion mother cells

21 January 2018

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Translational complexity of the fragile x mental retardation protein: insights from the fly.

21 January 2018

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Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

21 January 2018

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Circuit and plasticity defects in the developing somatosensory cortex of FMR1 knock-out mice.

21 January 2018

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Growth factors regulate the survival and fate of cells derived from human neurospheres.

21 January 2018

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Fragile X protein controls neural stem cell proliferation in the Drosophila brain

21 January 2018

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Altered differentiation of neural stem cells in fragile X syndrome

21 January 2018

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Nutrition-responsive glia control exit of neural stem cells from quiescence.

21 January 2018

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Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment

21 January 2018

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The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits

21 January 2018

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Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

21 January 2018

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Mildly impaired water maze performance in male Fmr1 knockout mice.

21 January 2018

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Short-term and long-term survival of new neurons in the rat dentate gyrus

21 January 2018

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A point mutation in the FMR-1 gene associated with fragile X mental retardation

21 January 2018

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The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

21 January 2018

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A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome.

21 January 2018

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Fmr1 knockout mouse has a distinctive strain-specific learning impairment.

21 January 2018

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Drosophila lacking dfmr1 activity show defects in circadian output and fail to maintain courtship interest

21 January 2018

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Regeneration of a germinal layer in the adult mammalian brain

21 January 2018

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Courting a cure for fragile X.

21 January 2018

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Correction of fragile X syndrome in mice.

21 January 2018

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Calcium oscillations increase the efficiency and specificity of gene expression

21 January 2018

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The Drosophila anachronism locus: a glycoprotein secreted by glia inhibits neuroblast proliferation

21 January 2018

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Insights into neural stem cell biology from flies.

21 January 2018

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Brain anatomy, gender and IQ in children and adolescents with fragile X syndrome

21 January 2018

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Anatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging

21 January 2018

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Effect of genetic background on acoustic startle response in fragile X knockout mice

21 January 2018

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Fragile X protein controls the efficacy of mRNA transport in Drosophila neurons

21 January 2018

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Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox

21 January 2018

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Mammalian neural stem cells

21 January 2018

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Olfactory bulb mitral cell dendritic pruning abnormalities in a mouse model of the Fragile-X mental retardation syndrome: further support for FMRP's involvement in dendritic development.

21 January 2018

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Understanding fragile X syndrome: insights from retarded flies

21 January 2018

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Neuroanatomy of fragile X syndrome is associated with aberrant behavior and the fragile X mental retardation protein (FMRP).

21 January 2018

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The cell biology of neurogenesis

21 January 2018

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Neuronal intranuclear inclusions in a new cerebellar tremor/ataxia syndrome among fragile X carriers

21 January 2018

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A nonsense mutation in FMR1 causing fragile X syndrome

21 January 2018

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Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature-appearing profile of dendritic spines.

21 January 2018

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Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

21 January 2018

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A de novo deletion in FMR1 in a patient with developmental delay

21 January 2018

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Fragile X syndrome. Clinical, electroencephalographic and neuroimaging characteristics.

21 January 2018

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The fragile X premutation: into the phenotypic fold

21 January 2018

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Compulsive, self-injurious, and autistic behavior in children and adolescents with fragile X syndrome

21 January 2018

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Methylation analysis of CGG sites in the CpG island of the human FMR1 gene

21 January 2018

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Autistic behavior in children with fragile X syndrome: prevalence, stability, and the impact of FMRP.

21 January 2018

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Teasing apart the heterogeneity of autism: Same behavior, different brains in toddlers with fragile X syndrome and autism

21 January 2018

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Tissue specific expression of FMR-1 provides evidence for a functional role in fragile X syndrome.

21 January 2018

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Analysis of neocortex in three males with the fragile X syndrome

21 January 2018

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Region-specific alterations in brain development in one- to three-year-old boys with fragile X syndrome

21 January 2018

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Morphometric spatial patterns differentiating boys with fragile X syndrome, typically developing boys, and developmentally delayed boys aged 1 to 3 years

21 January 2018

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Fragile X syndrome: molecular mechanisms of cognitive dysfunction

21 January 2018

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Altered synaptic plasticity in a mouse model of fragile X mental retardation

21 January 2018

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A role for the Drosophila fragile X-related gene in circadian output

21 January 2018

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Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.

21 January 2018

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Proliferation pattern of postembryonic neuroblasts in the brain of Drosophila melanogaster

21 January 2018

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Astrocytes prevent abnormal neuronal development in the fragile x mouse.

21 January 2018

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Reliability and validity of MRI measurement of the amygdala and hippocampus in children with fragile X syndrome

21 January 2018

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Autism spectrum disorder in fragile X syndrome: communication, social interaction, and specific behaviors.

21 January 2018

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A behavioral analysis of dentate gyrus function

21 January 2018

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Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n

21 January 2018

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3D pattern of brain abnormalities in Fragile X syndrome visualized using tensor-based morphometry

21 January 2018

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Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis

21 January 2018

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The fragile X mental retardation protein inhibits translation via interacting with mRNA

21 January 2018

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Gene, brain, and behavior relationships in fragile X syndrome: evidence from neuroimaging studies

21 January 2018

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The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.

21 January 2018

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Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells

21 January 2018

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A PEDIGREE OF MENTAL DEFECT SHOWING SEX-LINKAGE.

21 January 2018

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Brainy but not too brainy: starting and stopping neuroblast divisions in Drosophila.

21 January 2018

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Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome

21 January 2018

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RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice.

21 January 2018

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Fragile X mental retardation protein controls trailer hitch expression and cleavage furrow formation in Drosophila embryos

21 January 2018

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Stem cells and their niches

21 January 2018

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Decreased cerebellar posterior vermis size in fragile X syndrome: correlation with neurocognitive performance

21 January 2018

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Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome

21 January 2018

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Requirement for neurogenesis to proceed through the division of neuronal progenitors following differentiation of epidermal growth factor and fibroblast growth factor-2-responsive human neural stem cells

21 January 2018

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Developmental expression of FMRP in the astrocyte lineage: implications for fragile X syndrome.

21 January 2018

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Learning and memory functions of the Basal Ganglia

21 January 2018

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Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function.

21 January 2018

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Drosophila perlecan modulates FGF and hedgehog signals to activate neural stem cell division.

21 January 2018

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The pathophysiology of fragile x syndrome.

21 January 2018

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Neurodevelopmental effects of the FMR-1 full mutation in humans.

21 January 2018

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Neuroanatomy of fragile X syndrome: the posterior fossa

21 January 2018

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Contribution of the FMR1 gene mutation to human intellectual dysfunction

21 January 2018

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Neuroanatomy of fragile X syndrome: the temporal lobe

21 January 2018

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Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system

21 January 2018

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Conditional expression of UAS-transgenes in the adult eye with a new gene-switch vector system.

21 January 2018

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Adult fragile X syndrome. Clinico-neuropathologic findings.

21 January 2018

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FMRP regulates the transition from radial glial cells to intermediate progenitor cells during neocortical development.

21 January 2018

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Fragile X mental retardation protein regulates new neuron differentiation in the adult olfactory bulb

21 January 2018

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The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

21 January 2018

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Regulating neural proliferation in the Drosophila CNS.

21 January 2018

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Functional topography in the human cerebellum: a meta-analysis of neuroimaging studies

21 January 2018

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The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo

21 January 2018

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Aberrant differentiation of glutamatergic cells in neocortex of mouse model for fragile X syndrome

21 January 2018

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Spatial and temporal patterns of neurogenesis in the central nervous system of Drosophila melanogaster

21 January 2018

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Spatial learning, contextual fear conditioning and conditioned emotional response in Fmr1 knockout mice.

21 January 2018

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Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

21 January 2018

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Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein

21 January 2018

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Synaptic synthesis of the Fragile X protein: possible involvement in synapse maturation and elimination.

21 January 2018

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Calcium regulation of neuronal gene expression

21 January 2018

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21 January 2018

On mammary stem cells

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Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.

21 January 2018

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A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability

21 January 2018

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All muscle satellite cells are equal, but are some more equal than others?

21 January 2018

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A mouse model of the human Fragile X syndrome I304N mutation

21 January 2018

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Come FLY with us: toward understanding fragile X syndrome

21 January 2018

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Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function

21 January 2018

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Fathoming fragile X in fruit flies

21 January 2018

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Mechanisms and functional implications of adult neurogenesis

21 January 2018

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Trophic interactions between astroglial cells and hippocampal neurons in culture

21 January 2018

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7 January 2021

Molecular analysis of the locus elav in Drosophila melanogaster: a gene whose embryonic expression is neural specific

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7 January 2021

Induction of long-term depression in cerebellar Purkinje cells requires a rapidly turned over protein

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7 January 2021

Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells

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7 January 2021

Abnormal development of dendritic spines in FMR1 knock-out mice

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7 January 2021

Diagnostic molecular genetics of the fragile X.

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7 January 2021

Identifiers

DOI

10.1002/DVG.20745

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24 August 2017

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