(Q37859678)

24 August 2017

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title

Toll-like receptor signaling: common pathways that drive cardiovascular disease and rheumatoid arthritis (English)

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24 August 2017

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cardiovascular disease

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1

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24 August 2017

Niccolo Terrando

2

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24 August 2017

Kim S Midwood

series ordinal

3

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24 August 2017

language of work or name

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1 April 2011

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Arthritis Care and Research

24 August 2017

published in

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24 August 2017

volume

63

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24 August 2017

issue

4

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24 August 2017

page(s)

500-511

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The mortality of rheumatoid arthritis

24 August 2017

cites work

1 reference

Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis

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High ten-year risk of cardiovascular disease in newly diagnosed rheumatoid arthritis patients: a population-based cohort study

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Increased thickness of the arterial intima-media detected by ultrasonography in patients with rheumatoid arthritis

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Atherosclerosis in rheumatoid arthritis: morphologic evidence obtained by carotid ultrasound.

21 January 2018

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Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study

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Utility of the Framingham risk score to predict the presence of coronary atherosclerosis in patients with rheumatoid arthritis

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Joint swelling as a predictor of death from cardiovascular disease in a population study of Pima Indians

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Traditional cardiovascular risk factors measured prior to the onset of inflammatory polyarthritis

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21 January 2018

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The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus

21 January 2018

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From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II.

21 January 2018

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Inflammation, atherosclerosis, and coronary artery disease

21 January 2018

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

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DAMPening inflammation by modulating TLR signalling

21 January 2018

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Structures of the toll-like receptor family and its ligand complexes

21 January 2018

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The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress.

21 January 2018

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Toll-like receptors in inflammation, infection and cancer

21 January 2018

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Negative regulation of toll-like receptor-mediated immune responses

21 January 2018

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Targeting Toll-like receptors in autoimmunity.

21 January 2018

1 reference

Selective use of TRAM in lipopolysaccharide (LPS) and lipoteichoic acid (LTA) induced NF-kappaB activation and cytokine production in primary human cells: TRAM is an adaptor for LPS and LTA signaling.

21 January 2018

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The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis

21 January 2018

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Bartonella quintana lipopolysaccharide is a natural antagonist of Toll-like receptor 4

21 January 2018

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Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis.

21 January 2018

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Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures

21 January 2018

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The role of Toll-like receptor signalling in the pathogenesis of arthritis

21 January 2018

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Fluoxetine and citalopram exhibit potent antiinflammatory activity in human and murine models of rheumatoid arthritis and inhibit toll-like receptors

21 January 2018

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Arthritis in rats after systemic injection of streptococcal cells or cell walls

21 January 2018

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Essential roles of Toll-like receptor-4 signaling in arthritis induced by type II collagen antibody and LPS.

21 January 2018

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Interleukin 1 receptor dependence of serum transferred arthritis can be circumvented by toll-like receptor 4 signaling

21 January 2018

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Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

21 January 2018

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Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation

21 January 2018

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Vessel-specific Toll-like receptor profiles in human medium and large arteries

21 January 2018

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Vascular cell responsiveness to Toll-like receptor ligands in carotid atheroma.

21 January 2018

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Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation

21 January 2018

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TLR-4 agonistic lipopolysaccharide upregulates interleukin-8 at the transcriptional and post-translational level in vascular smooth muscle cells

21 January 2018

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Regulation of endotoxin-induced proinflammatory activation in human coronary artery cells: expression of functional membrane-bound CD14 by human coronary artery smooth muscle cells

21 January 2018

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Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll-like receptor 4 signaling.

21 January 2018

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Toll-like receptor 2 mediates persistent chemokine release by Chlamydia pneumoniae-infected vascular smooth muscle cells

21 January 2018

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Toll-like receptor 3 signaling evokes a proinflammatory and proliferative phenotype in human vascular smooth muscle cells.

21 January 2018

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Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL.

21 January 2018

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Enhanced expression of TLR4 in smooth muscle cells in human atherosclerotic coronary arteries

21 January 2018

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Increased expression of Toll like receptor 4 on peripheral-blood mononuclear cells in patients with coronary arteriosclerosis disease.

21 January 2018

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Expansion of circulating Toll-like receptor 4-positive monocytes in patients with acute coronary syndrome

21 January 2018

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Toll-like receptor 4 expressions on peripheral blood monocytes were enhanced in coronary artery disease even in patients with low C-reactive protein.

21 January 2018

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Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis

21 January 2018

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Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

21 January 2018

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Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

21 January 2018

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Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

21 January 2018

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Modulation of atherosclerosis in mice by Toll-like receptor 2

21 January 2018

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Toll-like receptor-2 mediates diet and/or pathogen associated atherosclerosis: proteomic findings

21 January 2018

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Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids.

21 January 2018

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Atherosclerosis and plasma and liver lipids in nine inbred strains of mice

21 January 2018

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Infectious agents are not necessary for murine atherogenesis

21 January 2018

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Toll-like receptor 2 stimulation induces intimal hyperplasia and atherosclerotic lesion development

21 January 2018

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Lipopolysaccharide stimulation of RAW 264.7 macrophages induces lipid accumulation and foam cell formation

21 January 2018

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Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

21 January 2018

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A combination of Lox-1 and Nox1 regulates TLR9-mediated foam cell formation

21 January 2018

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Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake

21 January 2018

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Chlamydia pneumoniae--induced macrophage foam cell formation is mediated by Toll-like receptor 2.

21 January 2018

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Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation

21 January 2018

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TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis

21 January 2018

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Toll-like receptors induce a phagocytic gene program through p38.

21 January 2018

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Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism

21 January 2018

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Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions.

21 January 2018

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TLR4 links innate immunity and fatty acid-induced insulin resistance

21 January 2018

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The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes

21 January 2018

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Attenuation of the cardiovascular and metabolic complications of obesity in CD14 knockout mice

21 January 2018

1 reference

Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5

21 January 2018

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Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice

21 January 2018

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Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells

21 January 2018

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Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2.

21 January 2018

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CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

21 January 2018

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Toll-like receptor 2 mediates apolipoprotein CIII-induced monocyte activation

21 January 2018

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Serum amyloid A and lipoprotein retention in murine models of atherosclerosis

21 January 2018

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Cutting edge: TLR2 is a functional receptor for acute-phase serum amyloid A

21 January 2018

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Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.

21 January 2018

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Regulation of extravascular coagulation by microvascular permeability.

21 January 2018

1 reference

The role of tenascin-C in tissue injury and tumorigenesis

21 January 2018

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Transcriptional regulation of the endogenous danger signal tenascin-C: a novel autocrine loop in inflammation.

21 January 2018

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Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease.

21 January 2018

1 reference

The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages

21 January 2018

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Athsq1 is an atherosclerosis modifier locus with dramatic effects on lesion area and prominent accumulation of versican

21 January 2018

1 reference

The immunologic detection and characterization of cartilage proteoglycan degradation products in synovial fluids of patients with arthritis

21 January 2018

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Hyaluronan fragments act as an endogenous danger signal by engaging TLR2.

21 January 2018

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Hyaluronan fragments stimulate endothelial recognition of injury through TLR4.

21 January 2018

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Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.

21 January 2018

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Overexpression of hyaluronan in the tunica media promotes the development of atherosclerosis

21 January 2018

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High mobility group box chromosomal protein 1, a DNA binding cytokine, induces arthritis

21 January 2018

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The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells

21 January 2018

1 reference

Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice

21 January 2018

1 reference

The orchestra of Toll-like receptors and their potential role in frequently occurring rheumatic conditions

21 January 2018

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Accelerated atherogenesis in autoimmune rheumatic diseases

21 January 2018

1 reference

Severe extra-articular disease manifestations are associated with an increased risk of first ever cardiovascular events in patients with rheumatoid arthritis

21 January 2018

1 reference

Tumour necrosis factor antagonists improve disease activity but not arterial stiffness in rheumatoid arthritis.

21 January 2018

1 reference

Reduction in the incidence of myocardial infarction in patients with rheumatoid arthritis who respond to anti-tumor necrosis factor alpha therapy: results from the British Society for Rheumatology Biologics Register

21 January 2018

1 reference

Methotrexate and mortality in patients with rheumatoid arthritis: a prospective study

21 January 2018

1 reference

Anti-inflammatory effects of statins: clinical evidence and basic mechanisms

21 January 2018

1 reference

Statin use in rheumatoid arthritis in relation to actual cardiovascular risk: evidence for substantial undertreatment of lipid-associated cardiovascular risk?

21 January 2018

1 reference

Testing the inflammatory hypothesis of atherothrombosis: scientific rationale for the cardiovascular inflammation reduction trial (CIRT).

21 January 2018

1 reference

Targeting Toll-like receptors: emerging therapeutics?

21 January 2018

1 reference

Suppressive oligonucleotides protect against collagen-induced arthritis in mice

21 January 2018

1 reference

HMGB1 as a mediator of necrosis-induced inflammation and a therapeutic target in arthritis

21 January 2018

1 reference

High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease

21 January 2018

1 reference

Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis

21 January 2018

1 reference

21 January 2018

1 reference

Reduction of CpG-induced arthritis by suppressive oligodeoxynucleotides

21 January 2018

1 reference

Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance

21 January 2018

1 reference

Enhanced Response of Blood Monocytes to In Vitro Lipopolysaccharide-Challenge in Patients With Recurrent Unstable Angina

21 January 2018

1 reference

Local Overexpression of Toll-Like Receptors at the Vessel Wall Induces Atherosclerotic Lesion Formation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ACR.20382

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24 August 2017

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