(Q37862746)

24 August 2017

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title

Host genetics in immune-mediated hepatitis C virus clearance (English)

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24 August 2017

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Julia Schmidt

1

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24 August 2017

Robert Thimme

series ordinal

2

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24 August 2017

Christoph Neumann-Haefelin

series ordinal

3

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24 August 2017

publication date

1 April 2011

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24 August 2017

published in

Biomarkers in Medicine

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24 August 2017

volume

5

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24 August 2017

issue

2

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24 August 2017

page(s)

155-169

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Hepatitis C: molecular virology and antiviral targets

24 August 2017

cites work

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Hepatitis C virus infection

21 January 2018

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Flying under the radar: the immunobiology of hepatitis C.

21 January 2018

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Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence

21 January 2018

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Adaptive immunity to the hepatitis C virus

21 January 2018

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Intracellular innate immune cascades and interferon defenses that control hepatitis C virus

21 January 2018

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Hepatitis C and Innate Immunity: Recent Advances

21 January 2018

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Natural killer cells and hepatitis C: action and reaction

21 January 2018

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Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection

21 January 2018

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Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C

21 January 2018

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Analysis of successful immune responses in persons infected with hepatitis C virus

21 January 2018

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Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease

21 January 2018

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Determinants of viral clearance and persistence during acute hepatitis C virus infection

21 January 2018

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Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection

21 January 2018

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HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help

21 January 2018

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Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C

21 January 2018

1 reference

Clearance of hepatitis C viremia associated with cellular immunity in the absence of seroconversion in the hepatitis C incidence and transmission in prisons study cohort

21 January 2018

1 reference

Host and viral factors contributing to CD8+ T cell failure in hepatitis C virus infection

21 January 2018

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Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation

21 January 2018

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Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

21 January 2018

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PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

21 January 2018

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Regulatory T cells and viral liver disease

21 January 2018

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T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection.

21 January 2018

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An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.

21 January 2018

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Mutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to man

21 January 2018

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Cellular immune selection with hepatitis C virus persistence in humans

21 January 2018

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Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection

21 January 2018

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CD8 Epitope Escape and Reversion in Acute HCV Infection

21 January 2018

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Host genetic determinants of spontaneous hepatitis C clearance

21 January 2018

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Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source

21 January 2018

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HLA-Cw*04 and hepatitis C virus persistence

21 January 2018

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Specific human leukocyte antigen class I and II alleles associated with hepatitis C virus viremia

21 January 2018

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Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes

21 January 2018

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Evidence for human leukocyte antigen heterozygote advantage against hepatitis C virus infection

21 January 2018

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Impact of MHC class I diversity on immune control of immunodeficiency virus replication

21 January 2018

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Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope

21 January 2018

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Protective effect of HLA-B57 on HCV genotype 2 infection in a West African population

21 January 2018

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The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T-cell count in individuals coinfected with HIV-1.

21 January 2018

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HLA-B27 and the pathogenesis of spondyloarthropathies

21 January 2018

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Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution

21 January 2018

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Human leukocyte antigen-associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution

21 January 2018

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Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure

21 January 2018

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High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection

21 January 2018

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Effect of immune pressure on hepatitis C virus evolution: insights from a single-source outbreak

21 January 2018

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Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes

21 January 2018

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Degree of cross-genotype reactivity of hepatitis C virus-specific CD8+ T cells directed against NS3.

21 January 2018

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Evidence of Viral Adaptation to HLA Class I-Restricted Immune Pressure in Chronic Hepatitis C Virus Infection

21 January 2018

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HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection

21 January 2018

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High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population.

21 January 2018

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Distribution of the HLA class I allele in chronic hepatitis C and its association with serum ALT level in chronic hepatitis C.

21 January 2018

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Association of human leucocyte antigen Class I (HLA-A and HLA-B) with chronic hepatitis C virus infection in Egyptian patients.

21 January 2018

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Discordant role of CD4 T-cell response relative to neutralizing antibody and CD8 T-cell responses in acute hepatitis C.

21 January 2018

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Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses.

21 January 2018

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Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response

21 January 2018

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Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers

21 January 2018

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Transient immunological control during acute hepatitis C virus infection: ex vivo analysis of helper T-cell responses

21 January 2018

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A comparative review of HLA associations with hepatitis B and C viral infections across global populations

21 January 2018

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Restriction fragment length polymorphism of adhesin gene hpaA from different Helicobacter pylori strains of Chongqing, China

21 January 2018

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Host genetic determinants in hepatitis C virus infection

21 January 2018

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The natural course of hepatitis C virus infection after 22 years in a unique homogenous cohort: spontaneous viral clearance and chronic HCV infection

21 January 2018

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Association of the HLA-DRB1*01 allele with spontaneous viral clearance in an Irish cohort infected with hepatitis C virus via contaminated anti-D immunoglobulin

21 January 2018

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Viral clearance in hepatitis C (1b) infection: relationship with human leukocyte antigen class II in a homogeneous population

21 January 2018

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Racial differences in HLA class II associations with hepatitis C virus outcomes

21 January 2018

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Increased frequency of the HLA-DR15 (B1*15011) allele in German patients with self-limited hepatitis C virus infection.

21 January 2018

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Human leukocyte antigen class II associations with hepatitis C virus clearance and virus‐specific CD4 T cell response among Caucasians and African Americans

21 January 2018

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Minimal T-cell-stimulatory sequences and spectrum of HLA restriction of immunodominant CD4+ T-cell epitopes within hepatitis C virus NS3 and NS4 proteins

21 January 2018

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Broad Specificity of Virus-Specific CD4+ T-Helper-Cell Responses in Resolved Hepatitis C Virus Infection

21 January 2018

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Conserved hepatitis C virus sequences are highly immunogenic for CD4(+) T cells: implications for vaccine development.

21 January 2018

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Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes

21 January 2018

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Longitudinal mapping of protective CD4+ T cell responses against HCV: analysis of fluctuating dominant and subdominant HLA-DR11 restricted epitopes.

21 January 2018

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HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection

21 January 2018

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Interaction of NK inhibitory receptor genes with HLA-C and MHC class II alleles in Hepatitis C virus infection outcome

21 January 2018

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Protective KIR-HLA interactions for HCV infection in intravenous drug users.

21 January 2018

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Influence of inhibitory killer immunoglobulin-like receptors and their HLA-C ligands on resolving hepatitis C virus infection

21 January 2018

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HLA-C and KIR genes in hepatitis C virus infection.

21 January 2018

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Consistent beneficial effects of killer cell immunoglobulin-like receptor 2DL3 and group 1 human leukocyte antigen-C following exposure to hepatitis C virus

21 January 2018

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Effect of Killer Immunoglobulin-Like Receptors in the Response to Combined Treatment in Patients with Chronic Hepatitis C Virus Infection

21 January 2018

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Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

21 January 2018

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Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study

21 January 2018

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IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

21 January 2018

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Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

21 January 2018

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Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin

21 January 2018

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The recent breakthroughs in the understanding of host genomics in hepatitis C.

21 January 2018

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Interleukin-28B genetic variants and hepatitis virus infection by different viral genotypes

21 January 2018

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Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients.

21 January 2018

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Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients

21 January 2018

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Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.

21 January 2018

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An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response

21 January 2018

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Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.

21 January 2018

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Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

21 January 2018

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A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice

21 January 2018

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Acute hepatitis C: high rate of both spontaneous and treatment-induced viral clearance.

21 January 2018

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Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity

21 January 2018

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IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques

21 January 2018

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Unique Th1/Th2 Phenotypes Induced during Priming and Memory Phases by Use of Interleukin-12 (IL-12) or IL-28B Vaccine Adjuvants in Rhesus Macaques

21 January 2018

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IFN-lambda (IFN-lambda) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo

21 January 2018

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IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C.

21 January 2018

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Interferon signaling and treatment outcome in chronic hepatitis C

21 January 2018

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Alpha Interferon Induces Long-Lasting Refractoriness of JAK-STAT Signaling in the Mouse Liver through Induction of USP18/UBP43

21 January 2018

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The potential use of Toll-like receptor agonists to restore the dysfunctional immunity induced by hepatitis C virus.

21 January 2018

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Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection

21 January 2018

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Adaptive immune responses to hepatitis C virus: from viral immunobiology to a vaccine

21 January 2018

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Polymorphisms in interferon-induced genes and the outcome of hepatitis C virus infection: roles of MxA, OAS-1 and PKR.

21 January 2018

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Epistatic effects of immunoglobulin GM and KM allotypes on outcome of infection with hepatitis C virus

21 January 2018

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Genetic Markers of IgG Influence the Outcome of Infection with Hepatitis C Virus

21 January 2018

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Interleukin-10 promoter polymorphisms and the outcome of hepatitis C virus infection

21 January 2018

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Association of transforming growth factor-beta 1 functional polymorphisms with natural clearance of hepatitis C virus

21 January 2018

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Ethnic and geographical differences in HLA associations with the outcome of hepatitis C virus infection

21 January 2018

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Association between MHC class II alleles and clearance of circulating hepatitis C virus. Members of the Trent Hepatitis C Virus Study Group

21 January 2018

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Influence of MHC class II genotype on outcome of infection with hepatitis C virus. The HENCORE group. Hepatitis C European Network for Cooperative Research

21 January 2018

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Genes of the major histocompatibility complex class II influence the outcome of hepatitis C virus infection

21 January 2018

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Association between HLA class II alleles and protection from or susceptibility to chronic hepatitis C.

21 January 2018

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Decreased frequency of the HLA-DRB1*11 allele in patients with chronic hepatitis C virus infection

21 January 2018

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HLA class II genotypes associated with chronic hepatitis C virus infection and response to alpha-interferon treatment in Poland

21 January 2018

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IL-10 and TNF-α polymorphisms and the recovery from HCV infection

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/BMM.11.19

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24 August 2017

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