(Q37869660)

24 August 2017

1 reference

title

Dexmedetomidine and clonidine: from second- to first-line sedative agents in the critical care setting? (English)

1 reference

24 August 2017

1 reference

1 reference

C Pichot

1

1 reference

PubMed ID

21525113

24 August 2017

M Ghignone

series ordinal

2

1 reference

PubMed ID

21525113

24 August 2017

L Quintin

series ordinal

3

1 reference

24 August 2017

27 April 2011

1 reference

Journal of Intensive Care Medicine

24 August 2017

1 reference

24 August 2017

27

1 reference

24 August 2017

4

1 reference

24 August 2017

219-237

1 reference

The use of continuous i.v. sedation is associated with prolongation of mechanical ventilation

24 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Alpha2-adrenoceptor subtypes--unexpected functions for receptors and ligands derived from gene-targeted mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine raises blood pressure in severe idiopathic orthostatic hypotension

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Dexmedetomidine infusion for more than 24 hours in critically ill patients: sedative and cardiovascular effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine modulates locus coeruleus metabolic hyperactivity induced by stress in behaving rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Effect of clonidine and gamma-aminobutyric acid on the discharges of medullo-spinal sympathoexcitatory neurons in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Cardioinhibitory actions of clonidine assessed by cardiac vagal motoneuron recordings.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

The brain nucleus locus coeruleus: restricted afferent control of a broad efferent network

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

The haemodynamic and hormonal responses after clonidine occur independently of sedation in essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Therapeutic effects of evening administration of guanabenz and clonidine on morning hypertension: evaluation using home-based blood pressure measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine: a new antihypertensive agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Apparent resistance to hypotensive effect of clonidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine effects on all-night human sleep: opposite action of low- and medium-dose clonidine on human NREM-REM sleep proportion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Electroencephalogram spindle activity during dexmedetomidine sedation and physiological sleep

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Therapy of alcohol withdrawal syndrome in intensive care unit patients following trauma: results of a prospective, randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine as a sedative adjunct in intensive care

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Bispectral index-guided sedation with dexmedetomidine in intensive care: a prospective, randomized, double blind, placebo-controlled phase II study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

The role of the alpha2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Use of dexmedetomidine in children after cardiac and thoracic surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine blocks acute opiate-withdrawal symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Respiratory, metabolic and hemodynamic effects of clonidine in ventilated patients presenting with withdrawal syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Autonomic dysfunction in tetanus - what lessons can be learnt with specific reference to alpha-2 agonists?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Practice of sedation and analgesia in German intensive care units: results of a national survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Impact of clonidine administration on delirium and related respiratory weaning after surgical correction of acute type-A aortic dissection: results of a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Preliminary UK experience of dexmedetomidine, a novel agent for postoperative sedation in the intensive care unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Comparison between dexmedetomidine and propofol for sedation in the intensive care unit: patient and clinician perceptions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Respiratory effects of dexmedetomidine in the surgical patient requiring intensive care

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Dexmedetomidine: applications in pediatric critical care and pediatric anesthesiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

A phase II study to evaluate the efficacy of dexmedetomidine for sedation in the medical intensive care unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Adjunctive dexmedetomidine therapy in the intensive care unit: a retrospective assessment of impact on sedative and analgesic requirements, levels of sedation and analgesia, and ventilatory and hemodynamic parameters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Memory enhancement in Korsakoff's psychosis by clonidine: further evidence for a noradrenergic deficit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

The efficacy of dexmedetomidine in patients with noninvasive ventilation: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Safety and efficacy of dexmedetomidine in neurosurgical patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

A new therapy of post-trauma brain oedema based on haemodynamic principles for brain volume regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Improved outcome after severe head injury with a new therapy based on principles for brain volume regulation and preserved microcirculation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

A standardized neurosurgical neurointensive therapy directed toward vasogenic edema after severe traumatic brain injury: clinical results.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Volume-targeted therapy of increased intracranial pressure: the Lund concept unifies surgical and non-surgical treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine antinociceptive activity: Effects of drugs influencing central monoaminergic and cholinergic mechanisms in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Spinal clonidine inhibits neural firing in locus coeruleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Epidural clonidine used as the sole analgesic agent during and after abdominal surgery. A dose-response study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Dexmedetomidine as a total intravenous anesthetic agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Anesthesia for a patient with morbid obesity using dexmedetomidine without narcotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Tracheal resection in the morbidly obese patient: the role of dexmedetomidine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Pharmacological studies on a possible role of central noradrenaline neurons in respiratory control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Possible involvement of central adrenaline neurons in vasomotor and respiratory control. Studies with clonidine and its interactions with piperoxane and yohimbine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Dexmedetomidine, a selective alpha 2-agonist, does not potentiate the cardiorespiratory depression of alfentanil in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

The effects of intravenous clonidine on ventilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Oral clonidine premedication decreases energy expenditure in human volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine premedication in patients with sleep apnea syndrome: a randomized, double-blind, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Bronchial effects of alpha 2-adrenoceptor agonists and of other antihypertensive agents in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Effects of the alpha2-adrenoceptor agonist dexmedetomidine on bronchoconstriction in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Additional Experience with Dexmedetomidine in Pediatric Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Feasibility of dexmedetomidine in facilitating extubation in the intensive care unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

The central modulatory effect of clonidine on the cardiodepressor reflex after suppression of synthesis and storage of noradrenaline

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Effect of clonidine on catechol metabolism in the rostral ventrolateral medulla: an in vivo electrochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine modulates the ventrolateral medullary catechol metabolic hyperactivity induced by hypotension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Short-term effects of intravenous clonidine in congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine in congestive heart failure: a vasodilator with negative inotropic effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Suppressing sympathetic activation in congestive heart failure. A new therapeutic strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine pretreatment enhances the sensitivity of the beta-noradrenergic receptor coupled adenylate cyclase system in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Up-regulation of beta-adrenoceptors on circulating mononuclear cells after reduction of central sympathetic outflow by clonidine in normal subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

HAeMODYNAMIC STUDIES WITH METHYLDOPA: EFFECT ON CARDIAC OUTPUT AND RESPONSE TO PRESSOR AMINES

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

ICU sedation after coronary artery bypass graft surgery: dexmedetomidine-based versus propofol-based sedation regimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Bradycardia during dexmedetomidine and therapeutic hypothermia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Intravenous clonidine infusion in infants after cardiovascular surgery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Use of oral clonidine for sedation in ventilated paediatric intensive care patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

The use of dexmedetomidine in critically ill children

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

A new dosing protocol reduces dexmedetomidine-associated hypotension in critically ill surgical patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Dexmedetomidine overdose in the perioperative setting

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

One hundred times the intended dose of caudal clonidine in three pediatric patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

High-dose dexmedetomidine-induced hypertension in a child with traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Sinus arrest associated with clonidine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Dexmedetomidine and cardiac arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Increased Sympathetic Nervous Activity and the Effects of Its Inhibition with Clonidine in Alcoholic Cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Preoperative alpha2-adrenergic receptor agonists prevent the deterioration of renal function after cardiac surgery: results of a randomized, controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

The pharmacokinetics of dexmedetomidine in volunteers with severe renal impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Pharmacokinetics of dexmedetomidine infusions for sedation of postoperative patients requiring intensive caret

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Clonidine attenuated early proinflammatory response in T-cell subsets after cardiac surgery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Central sympatholytics prolong survival in experimental sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Effects of dexmedetomidine on mortality rate and inflammatory responses to endotoxin-induced shock in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Dose- and time-related effects of dexmedetomidine on mortality and inflammatory responses to endotoxin-induced shock in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Effects of dexmedetomidine on adrenocortical function, and the cardiovascular, endocrine and inflammatory responses in post-operative patients needing sedation in the intensive care unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

A new era for sedation in ICU patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Comparison between dexmedetomidine and midazolam for sedation of eclampsia patients in the intensive care unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Effect of mivazerol on perioperative cardiac complications during non-cardiac surgery in patients with coronary heart disease: the European Mivazerol Trial (EMIT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Effect of clonidine on cardiovascular morbidity and mortality after noncardiac surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Pharmacologic myocardial protection in patients undergoing noncardiac surgery: a quantitative systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

21 January 2018

The inflammatory reflex

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

Dexmedetomidine: a real innovation or more of the same?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0885066610396815

21 January 2018

Identifiers

DOI

10.1177/0885066610396815

1 reference

24 August 2017

1 reference

PubMed ID

21525113