(Q37875779)

24 August 2017

1 reference

title

Danger signals activating innate immunity in graft-versus-host disease (English)

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24 August 2017

Robert Zeiser

1

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24 August 2017

Olaf Penack

series ordinal

2

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24 August 2017

Ernst Holler

series ordinal

3

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24 August 2017

Marco Idzko

series ordinal

4

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24 August 2017

15 May 2011

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Journal of Molecular Medicine

24 August 2017

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24 August 2017

89

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24 August 2017

833-845

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24 August 2017

9

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https://scigraph.springernature.com/pub.10.1007/s00109-011-0767-x

24 August 2017

0 references

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21 January 2018

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21 January 2018

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ATP drives lamina propria T(H)17 cell differentiation

21 January 2018

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Loss of ATP diphosphohydrolase activity with endothelial cell activation

21 January 2018

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Mechanisms of Release of Nucleotides and Integration of Their Action as P2X- and P2Y-Receptor Activating Molecules

21 January 2018

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Nucleotide receptors: an emerging family of regulatory molecules in blood cells

21 January 2018

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Molecular physiology of P2X receptors

21 January 2018

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Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

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The P2X7 receptor: a key player in IL-1 processing and release

21 January 2018

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Immune cell regulation by autocrine purinergic signalling

21 January 2018

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Extracellular nucleotides as negative modulators of immunity

21 January 2018

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ATP release from non-excitable cells.

21 January 2018

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Extracellular NAD and ATP: Partners in immune cell modulation.

21 January 2018

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Intravascular danger signals guide neutrophils to sites of sterile inflammation

21 January 2018

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ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors.

21 January 2018

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Purinergic signaling: a fundamental mechanism in neutrophil activation

21 January 2018

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Extracellular adenosine triphosphate and chronic obstructive pulmonary disease.

21 January 2018

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Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation

21 January 2018

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The purinergic receptor P2Y2 receptor mediates chemotaxis of dendritic cells and eosinophils in allergic lung inflammation

21 January 2018

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Dendritic cells exposed to extracellular adenosine triphosphate acquire the migratory properties of mature cells and show a reduced capacity to attract type 1 T lymphocytes.

21 January 2018

1 reference

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ATP gradients inhibit the migratory capacity of specific human dendritic cell types: implications for P2Y11 receptor signaling.

21 January 2018

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The P2Y11 receptor mediates the ATP-induced maturation of human monocyte-derived dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Thrombospondin-1 and indoleamine 2,3-dioxygenase are major targets of extracellular ATP in human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Mesenchymal stromal cells inhibit graft-versus-host disease of mice in a dose-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Purinergic control of T cell activation by ATP released through pannexin-1 hemichannels.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

NAD+ released during inflammation participates in T cell homeostasis by inducing ART2-mediated death of naive T cells in vivo.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Persistent antigenic stimulation alters the transcription program in T cells, resulting in antigen-specific tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Lack of the purinergic receptor P2X(7) results in resistance to contact hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Purinergic receptor inhibition prevents the development of smoke-induced lung injury and emphysema.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Increased expression of the pro-apoptotic ATP-sensitive P2X7 receptor in experimental and human glomerulonephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Extracellular ATP induces albuminuria in pregnant rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected by Porphyromonas gingivalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

P2X7 receptors regulate NKT cells in autoimmune hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Expression and regulation of cryopyrin and related proteins in rheumatoid arthritis synovium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

NALP1 in vitiligo-associated multiple autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

P2X7 receptor polymorphism and clinical outcomes in HLA-matched sibling allogeneic hematopoietic stem cell transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Extracellular matrix molecules: endogenous danger signals as new drug targets in kidney diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

The extra domain A of fibronectin activates Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Transcriptional regulation of the endogenous danger signal tenascin-C: a novel autocrine loop in inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Rasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Molecular identification of a danger signal that alerts the immune system to dying cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Human eosinophils recognize endogenous danger signal crystalline uric acid and produce proinflammatory cytokines mediated by autocrine ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Human Nod1 confers responsiveness to bacterial lipopolysaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

MyD88/TLR9 mediated immunopathology and gut microbiota dynamics in a novel murine model of intestinal graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Antimicrobial prophylaxis in allogeneic bone marrow transplantation. Guidelines of the infectious diseases working party (AGIHO) of the german society of haematology and oncology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Plasmacytoid dendritic cell dichotomy: identification of IFN-α producing cells as a phenotypically and functionally distinct subset

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

CARD15 mutations in Blau syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

NOD2 regulates hematopoietic cell function during graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

NOD2 polymorphisms predict severe acute graft-versus-host and treatment-related mortality in T-cell-depleted haematopoietic stem cell transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Insufficient evidence for association of NOD2/CARD15 or other inflammatory bowel disease-associated markers on GVHD incidence or other adverse outcomes in T-replete, unrelated donor transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Single nucleotide polymorphisms in the NOD2/CARD15 gene are associated with an increased risk of relapse and death for patients with acute leukemia after hematopoietic stem-cell transplantation with unrelated donors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

The role of bacteria and pattern recognition receptors in GVHD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Recipient NOD2/CARD15 status affects cellular infiltrates in human intestinal graft-versus-host disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Differential roles of IL-1 and TNF-alpha on graft-versus-host disease and graft versus leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Use of canakinumab in the cryopyrin-associated periodic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

P2X7 deficiency attenuates renal injury in experimental glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Discovery of a viral NLR homolog that inhibits the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Role of TNF-alpha and extracellular ATP in THP-1 cell activation following allergen exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Activation of macrophages by P2X7-induced microvesicles from myeloid cells is mediated by phospholipids and is partially dependent on TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Oxidized ATP inhibits T-cell-mediated autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

P2X7 Receptor Blockade Prevents ATP Excitotoxicity in Oligodendrocytes and Ameliorates Experimental Autoimmune Encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Activation of the IL-1β-Processing Inflammasome Is Involved in Contact Hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-011-0767-X

Mouse dendritic cells express the P2X7 purinergic receptor: characterization and possible participation in antigen presentation.

21 January 2018

1 reference

12 December 2020

Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome

1 reference

12 December 2020

Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontamination

1 reference

12 December 2020

Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis.

1 reference

12 December 2020

Role of Bacterial Microflora in Development of Intestinal Lesions From Graft-Versus-Host Reaction

1 reference

12 December 2020

Collagen fragments modulate innate immunity

1 reference

12 December 2020

Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines

1 reference

12 December 2020

Interleukin-1 blockade does not prevent acute graft-versus-host disease: results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation

1 reference

12 December 2020

Cutting edge: purinergic signaling regulates radical-mediated bacterial killing mechanisms in macrophages through a P2X7-independent mechanism

1 reference

12 December 2020

Probiotic effects on experimental graft-versus-host disease: let them eat yogurt

1 reference

12 December 2020

Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages

1 reference

12 December 2020

Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles

1 reference

12 December 2020

Extracellular ATP and TNF-alpha synergize in the activation and maturation of human dendritic cells

1 reference

12 December 2020

Activation of toll-like receptor 3 protects against DSS-induced acute colitis

1 reference

12 December 2020

A clinical phase I/II study of recombinant human interleukin-1 receptor in glucocorticoid-resistant graft-versus-host disease

1 reference

12 December 2020

P2X7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema

1 reference

12 December 2020

Anti-endotoxin antibody for prevention of acute GVHD

1 reference

12 December 2020

Effect of NOD2/CARD15 variants in T-cell depleted allogeneic stem cell transplantation

1 reference

12 December 2020

Stimulation of P2 receptors causes release of IL-1 -loaded microvesicles from human dendritic cells

1 reference

12 December 2020

Common variants in NLRP2 and NLRP3 genes are strong prognostic factors for the outcome of HLA-identical sibling allogeneic stem cell transplantation

1 reference

12 December 2020

Critical role of TLR9 in acute graft-versus-host disease

1 reference

12 December 2020

Graft-versus-host disease

1 reference

12 December 2020

Recipient NOD2/CARD15 variants: a novel independent risk factor for the development of bronchiolitis obliterans after allogeneic stem cell transplantation

1 reference

12 December 2020

Antimicrobial peptide response to blood translocation of bacterial DNA in Crohn's disease is affected by NOD2/CARD15 genotype

1 reference

12 December 2020

No impact of NOD2/CARD15 on outcome after SCT

1 reference

12 December 2020

Antibody titres to a rough-mutant strain of Escherichia coli in patients undergoing allogeneic bone-marrow transplantation. Evidence of a protective effect against graft-versus-host disease

1 reference

12 December 2020

Regulation of Human Mesenchymal Stem Cell Functions by an Autocrine Loop Involving NAD+ Release and P2Y11-Mediated Signaling

1 reference

12 December 2020

Prevention of graft versus host disease by inactivation of host antigen-presenting cells

1 reference

12 December 2020

Induction of human monocyte interleukin (IL)-8 by fibrinogen through the toll-like receptor pathway

1 reference

12 December 2020

NOD2/CARD15 variants are not a risk factor for clinical outcome after nonmyeloablative allogeneic stem cell transplantation

1 reference

12 December 2020

Adenosine receptors and inflammation

1 reference

12 December 2020

10.1007/S00109-011-0767-X

Identifiers

DOI

1 reference

24 August 2017

1 reference