(Q37884060)

24 August 2017

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title

A survey of small molecule glucagon receptor antagonists from recent patents (2006 - 2010). (English)

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24 August 2017

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Dong-Ming Shen

1

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24 August 2017

Songnian Lin

series ordinal

2

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24 August 2017

Emma R Parmee

series ordinal

3

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24 August 2017

language of work or name

English

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publication date

2 June 2011

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Expert Opinion on Therapeutic Patents

24 August 2017

published in

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24 August 2017

volume

21

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24 August 2017

issue

8

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24 August 2017

page(s)

1211-1240

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Biochemistry and molecular cell biology of diabetic complications

24 August 2017

cites work

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Hyperglycemia and the pathobiology of diabetic complications

21 January 2018

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Prevalence of diabetes among men and women in China

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

SGLT2 inhibition--a novel strategy for diabetes treatment

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Diabetes area participation analysis: a review of companies and targets described in the 2008 - 2010 patent literature

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Effects of a novel glucagon receptor antagonist (Bay 27-9955) on glucagon-stimulated glucose production in humans

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Glucagon as a target for the treatment of Type 2 diabetes

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Discovery of novel, potent, and orally active spiro-urea human glucagon receptor antagonists

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Discovery of potent, orally active benzimidazole glucagon receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Design and synthesis of conformationally constrained tri-substituted ureas as potent antagonists of the human glucagon receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Generation of mice expressing the human glucagon receptor with a direct replacement vector

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Hepatic glucagon receptor binding and glucose-lowering in vivo by peptidyl and non-peptidyl glucagon receptor antagonists

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

New beta-alanine derivatives are orally available glucagon receptor antagonists

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Novel glucagon receptor antagonists with improved selectivity over the glucose-dependent insulinotropic polypeptide receptor.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

A novel glucagon receptor antagonist, NNC 25-0926, blunts hepatic glucose production in the conscious dog.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Human glucagon receptor antagonists with thiazole cores. A novel series with superior pharmacokinetic properties.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Identification of alkylidene hydrazides as glucagon receptor antagonists.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Human glucagon receptor antagonists based on alkylidene hydrazides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Discovery and investigation of a novel class of thiophene-derived antagonists of the human glucagon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.587001

NMR-based screening of membrane protein ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Pathologic pancreatic endocrine cell hyperplasia

21 January 2018

1 reference

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Homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

21 January 2018

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Hepatic and glucagon-like peptide-1-mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors

21 January 2018

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Long-term inhibition of the glucagon receptor with a monoclonal antibody in mice causes sustained improvement in glycemic control, with reversible alpha-cell hyperplasia and hyperglucagonemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Differential expression of glucagon and glucagon-like peptide 1 receptors in mouse pancreatic alpha and beta cells in two models of alpha cell hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Characterization of a novel, non-peptidyl antagonist of the human glucagon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.587001

Allosteric modulators of class B G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.587001

10.1517/13543776.2011.587001

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference