(Q37884199)

13 October 2017

1 reference

title

Emerging approaches in the molecular design of receptor-selective peptide ligands: conformational, topographical and dynamic considerations (English)

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13 October 2017

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V J Hruby

1

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13 October 2017

F al-Obeidi

series ordinal

2

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13 October 2017

W Kazmierski

series ordinal

3

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13 October 2017

language of work or name

English

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publication date

1 June 1990

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13 October 2017

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13 October 2017

268

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13 October 2017

249-262

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13 October 2017

2

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Dehydrophenylalanyl analogs of bradykinin: Synthesis and biological activities

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Amphiphilic Secondary Structure: Design of Peptide Hormones

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr: a new highly potent and fully specific agonist for opiate delta-receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

[D-Pen2, L-Cys5]enkephalinamide and[D-Pen2, D-Cys5] enkephalinamide, conformationally constrained cyclic enkephalinamide analogs with delta receptor specificity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

half-Cys4,half-Cys10-alpha-Melanocyte-stimulating hormone: a cyclic alpha-melanotropin exhibiting superagonist biological activity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

(1-Beta-mercapto-beta,beta-diethylpropionic acid)-8-lysine-vasopressin, a potent inhibitor of 8-lysine-vasopressin and of oxytocin.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Conformational preferences of cyclopropyl peptides. Crystal structure of (E)-DL-1-benzamido-1-methoxycarbonyl-2-chlorcyclopropane (BCP).

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Aromatic-aromatic interaction: a mechanism of protein structure stabilization

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Molecular dynamics and minimum energy conformations of GnRH and analogs. A methodology for computer-aided drug design.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Nature of the charged-group effect on the stability of the C-peptide helix

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Loops in globular proteins: a novel category of secondary structure

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Design of peptides and proteins

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

A novel cyclic opioid peptide analog showing high preference for mu-receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Design and synthesis of somatostatin analogues with topographical properties that lead to highly potent and specific mu opioid receptor antagonists with greatly reduced binding at somatostatin receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Design and synthesis of conformationally constrained somatostatin analogues with high potency and specificity for mu opioid receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Turns in peptides and proteins

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Conformationally restricted analogs of somatostatin with high mu-opiate receptor specificity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

New delta-receptor antagonists

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Topographic probes of angiotensin and receptor: potent angiotensin II agonist containing diphenylalanine and long-acting antagonists containing biphenylalanine and 2-indan amino acid in position 8.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Conformationally restricted cyclic analogues of substance P: insight into the receptor binding process

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Opioid receptor selectivity of peptide models of beta-endorphin.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Design of potent linear alpha-melanotropin 4-10 analogues modified in positions 5 and 10

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Investigation of peripheral cholecystokinin receptor heterogeneity by cyclic and related linear analogues of CCK26-33: synthesis and biological properties.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Conformationally restricted C-terminal peptides of substance P. Synthesis, mass spectral analysis and pharmacological properties

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Conformationally restricted peptides through short-range cyclizations.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Subcutaneous administration of somatostatin analogs as a major factor in the enhancement of the duration of action

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Relative conformational rigidity in oxytocin and (1-penicillamine)-oxytocin: a proposal for the relationship of conformational flexibility to peptide hormone agonism and antagonism

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

ACTH: a short introductory review

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Dehydro-enkephalins. VI. Dehydroalanine3-enkephalin: a potent enkephalin analog for the delta opiate receptor

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131425

Synthesis and conformational study of a cyclic hexapeptide analogue of somatostatin: cyclo(Phe-D-Trp-Lys-Thr-o-AMPA)

1 September 2018

1 reference

12 December 2020

Anticoagulant peptides: nature of the interaction of the C-terminal region of hirudin with a noncatalytic binding site on thrombin

1 reference

12 December 2020

Conformationally constrained renin inhibitory peptides: gamma-lactam-bridged dipeptide isostere as conformational restriction

1 reference

12 December 2020

Synthesis, conformation, and immunosuppressive activity of a conformationally restricted cyclosporine lactam analogue

1 reference

12 December 2020

Conformationally restricted analogues of atriopeptin(103-125)amide

1 reference

12 December 2020

Studies on angiotensin converting enzyme inhibitors. 4. Synthesis and angiotensin converting enzyme inhibitory activities of 3-acyl-1-alkyl-2-oxoimidazolidine-4-carboxylic acid derivatives

1 reference

12 December 2020

Cyclic enkephalin analogues containing alpha-amino-beta-mercapto-beta,beta-pentamethylenepropionic acid at positions 2 or 5

1 reference

12 December 2020

Importance of the C-terminal alpha-helical structure for glucagon's biological activity

1 reference

12 December 2020

Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics

1 reference

12 December 2020

Solid-phase synthesis of [8-arginine]-vasopressin through a crystalline protected nonapeptide intermediate and biological properties of the hormone

1 reference

12 December 2020

Synthesis, biological activity, and tritiation of L-3, 4-dehydroproline-containing peptides

1 reference

12 December 2020

Design of potent antagonists of the vasopressor response to arginine-vasopressin

1 reference

12 December 2020

[1-beta-Mercapto-beta,beta-cyclopentamethylenepropionic acid),2-(O-methyl)tyrosine ]argine-vasopressin and [1-beta-mercapto-beta,beta-cyclopentamethylenepropionic acid)]argine-vasopressine, two highly potent antagonists of the vasopressor response t

1 reference

12 December 2020

Vasopressin analogs that antagonize antidiuretic responses by rats to the antidiuretic hormone

1 reference

12 December 2020

A potent cyclic hexapeptide analogue of somatostatin

1 reference

12 December 2020

Peptide antagonists of LH-RH: large increases in antiovulatory activities produced by basic D-amino acids in the six position

1 reference

12 December 2020

Design of potent and selective antagonists of the vasopressor responses to arginine-vasopressin

1 reference

12 December 2020

Conformational restrictions of biologically active peptides via amino acid side chain groups

1 reference

12 December 2020

Heterogeneity of glucagon receptors of rat hepatocytes: A synthetic peptide probe for the high affinity site

1 reference

12 December 2020

Two large immunogenic and antigenic myoglobin peptides and the effects of cyclisation

1 reference

12 December 2020

Synthesis and analysis of conformationally restricted analogs of peptide inhibitors of the angiotensin-converting enzyme

1 reference

12 December 2020

Interaction of calcium ions with gastrin fragments of increasing chain length

1 reference

12 December 2020

Tests of the helix dipole model for stabilization of α-helices

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2680249

1 reference

13 October 2017

1 reference

13 October 2017

1 reference