(Q37888960)

24 August 2017

1 reference

title

Applications of post-translational modifications of FoxO family proteins in biological functions (English)

1 reference

24 August 2017

Ying Zhao

1

1 reference

PubMed ID

21669942

24 August 2017

Yachen Wang

series ordinal

2

1 reference

PubMed ID

21669942

24 August 2017

Wei-Guo Zhu

series ordinal

3

1 reference

24 August 2017

13 June 2011

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Journal of Molecular Cell Biology

24 August 2017

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24 August 2017

3

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24 August 2017

276-282

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24 August 2017

5

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Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins

24 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Mdm2 induces mono-ubiquitination of FOXO4

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

PI3K: downstream AKTion blocks apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

FOXO transcription factors at the interface between longevity and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Roles of the Snf1/Rkin1/AMP-activated protein kinase family in the response to environmental and nutritional stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

O-GlcNAc regulates FoxO activation in response to glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway: implication of p27kip1 in cell response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

COP1 functions as a FoxO1 ubiquitin E3 ligase to regulate FoxO1-mediated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

A C. elegans mutant that lives twice as long as wild type

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Interplay between MEK and PI3 kinase signaling regulates the subcellular localization of protein kinases ERK1/2 and Akt upon oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

O-glycosylation of FoxO1 increases its transcriptional activity towards the glucose 6-phosphatase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

DAF-16 target genes that control C. elegans life-span and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Expression of the serum- and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

C terminus of Hsc70-interacting protein promotes smooth muscle cell proliferation and survival through ubiquitin-mediated degradation of FoxO1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

OutFOXOing disease and disability: the therapeutic potential of targeting FoxO proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Mammalian SIRT1 represses forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

The emerging roles of forkhead box (Fox) proteins in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Two 14-3-3 binding motifs are required for stable association of Forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

SGK1 regulation of epithelial sodium transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Protein kinases and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Akt activation promotes degradation of tuberin and FOXO3a via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Insulin Inhibition of Transcription Stimulated by the Forkhead Protein Foxo1 Is Not Solely due to Nuclear Exclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Regulation of FoxO activity by CBP/p300-mediated acetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Abelson virus transformation prevents TRAIL expression by inhibiting FoxO3a and NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Acetylation of FoxO1 activates Bim expression to induce apoptosis in response to histone deacetylase inhibitor depsipeptide treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

Chronic Protein Kinase B (PKB/c-akt) Activation Leads to Apoptosis Induced by Oxidative Stress-Mediated Foxo3a Transcriptional Up-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR013

21 January 2018

Identifiers

DOI

10.1093/JMCB/MJR013

1 reference

24 August 2017

1 reference

PubMed ID

21669942