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Regulation and function of miRNA-21 in health and disease.
scientific article published on 07 July 2011
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Europe PubMed Central
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3256347
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6 February 2020
review article
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title
Regulation and function of miRNA-21 in health and disease
(English)
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Europe PubMed Central
PMC publication ID
3256347
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712654%20AND%20SRC:MED&resulttype=core&format=json
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6 February 2020
author
Thomas Thum
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3
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Europe PubMed Central
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3256347
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6 February 2020
author name string
Regalla Kumarswamy
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1
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Europe PubMed Central
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3256347
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712654%20AND%20SRC:MED&resulttype=core&format=json
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6 February 2020
Ingo Volkmann
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2
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3256347
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6 February 2020
publication date
7 July 2011
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6 February 2020
published in
RNA Biology
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Europe PubMed Central
PMC publication ID
3256347
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6 February 2020
volume
8
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Europe PubMed Central
PMC publication ID
3256347
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712654%20AND%20SRC:MED&resulttype=core&format=json
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6 February 2020
issue
5
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Europe PubMed Central
PMC publication ID
3256347
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6 February 2020
page(s)
706-713
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6 February 2020
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
6 September 2017
Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
6 September 2017
Massive expansion of antigen-specific CD8+ T cells during an acute virus infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
6 September 2017
Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
6 September 2017
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
6 September 2017
NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
6 September 2017
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
6 September 2017
MicroRNA-21 expression in CD4+ T cells is regulated by STAT3 and is pathologically involved in Sézary syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
14 September 2017
Circulating microRNAs in plasma of patients with gastric cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
14 September 2017
Endothelial-mesenchymal transition in bleomycin-induced pulmonary fibrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
14 September 2017
BMP-6 inhibits microRNA-21 expression in breast cancer through repressing deltaEF1 and AP-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
14 September 2017
MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
14 September 2017
MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
14 September 2017
Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
14 September 2017
Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
14 September 2017
Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
14 September 2017
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
14 September 2017
Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
14 September 2017
Involvement of heparin-binding EGF-like growth factor and its processing by metalloproteinases in early epithelial morphogenesis of the submandibular gland
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
28 September 2017
Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
28 September 2017
Comparison of different miR-21 inhibitor chemistries in a cardiac disease model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
23 June 2018
Akt promotes endocardial-mesenchyme transition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
23 June 2018
Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
23 June 2018
The AP-1 site and MMP gene regulation: what is all the fuss about?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
23 June 2018
Mesenchymal miR-21 regulates branching morphogenesis in murine submandibular gland in vitro.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
Direct serum assay for microRNA-21 concentrations in early and advanced breast cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
Endothelial cell-derived endothelin-1 promotes cardiac fibrosis in diabetic hearts through stimulation of endothelial-to-mesenchymal transition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
PI3 kinase/Akt signaling mediates epithelial-mesenchymal transition in hypoxic hepatocellular carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
Is REST a regulator of pluripotency?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
Is REST required for ESC pluripotency?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
Role of AP1 element in the activation of human eNOS promoter by lysophosphatidylcholine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
TGF-beta1 gene transfer to the mouse colon leads to intestinal fibrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
Molecular and functional profiling of memory CD8 T cell differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
Lineage analysis in the chicken inner ear shows differences in clonal dispersion for epithelial, neuronal, and mesenchymal cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
1 September 2018
Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256347
retrieved
3 December 2018
Monitoring tissue repair and fibrosis from a distance
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21712654
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Epithelial-mesenchymal interactions in pulmonary fibrosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21712654
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High-resolution genomic and expression analyses of copy number alterations in breast tumors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21712654
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
MicroRNA-21 expression in neonatal blood associated with antenatal immunoglobulin E production and development of allergic rhinitis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21712654
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21712654
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4161/RNA.8.5.16154
1 reference
stated in
Europe PubMed Central
PMC publication ID
3256347
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
PMC publication ID
3256347
1 reference
stated in
Europe PubMed Central
PMC publication ID
3256347
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
PubMed publication ID
21712654
1 reference
stated in
Europe PubMed Central
PMC publication ID
3256347
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21712654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
ResearchGate publication ID
51451549
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