(Q37898344)

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The translational challenge in the development of new and effective therapies for endometriosis: a review of confidence from published preclinical efficacy studies.

scientific article published on 06 July 2011

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6 February 2020

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Europe PubMed Central

The translational challenge in the development of new and effective therapies for endometriosis: a review of confidence from published preclinical efficacy studies (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21733981%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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Nicholas A Pullen

1

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Europe PubMed Central

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6 February 2020

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Claire L Birch

2

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6 February 2020

Garry J Douglas

3

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6 February 2020

Qasim Hussain

4

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6 February 2020

Ingrid Pruimboom-Brees

5

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6 February 2020

Rosalind J Walley

6

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6 February 2020

publication date

6 July 2011

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6 February 2020

Human Reproduction Update

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Europe PubMed Central

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6 February 2020

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6 February 2020

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6 February 2020

791-802

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6 February 2020

Revised American Society for Reproductive Medicine classification of endometriosis: 1996

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Diagnosis of endometriosis by detection of nerve fibres in an endometrial biopsy: a double blind study.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

A long-acting tumor necrosis factor alpha-binding protein demonstrates activity in both in vitro and in vivo models of endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Efficacy of anti-tumor necrosis factor therapy in the treatment of spontaneous endometriosis in baboons

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

A novel noninvasive model of endometriosis for monitoring the efficacy of antiangiogenic therapy

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Innervation of ectopic endometrium in a rat model of endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

The pains of endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Density of small diameter sensory nerve fibres in endometrium: a semi-invasive diagnostic test for minimal to mild endometriosis.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Inhibition of CD36-dependent phagocytosis by prostaglandin E2 contributes to the development of endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

The treatment with a COX-2 specific inhibitor is effective in the management of pain related to endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Combined laparoscopic surgery and pentoxifylline therapy for treatment of endometriosis-associated infertility: a preliminary trial

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Nonhuman primate models for translational research in endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Pain in endometriosis: effectiveness of medical and surgical management

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Endocannabinoid involvement in endometriosis.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Regression of endometrial explants in rats treated with the cyclooxygenase-2 inhibitor rofecoxib

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Nonsteroidal antiinflammatory drugs differentially suppress endometriosis in a murine model

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Treatment with anti-TNF monoclonal antibody (c5N) reduces the extent of induced endometriosis in the baboon

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Effects of anti-TNF-mAb treatment on pregnancy in baboons with induced endometriosis.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Molecular profiling of experimental endometriosis identified gene expression patterns in common with human disease

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Animal models in endometriosis research

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Recurrence of endometriosis and its control

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

A call for more transparency of registered clinical trials on endometriosis.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Aberrant expression of regulators of cell-fate found in eutopic endometrium is found in matched ectopic endometrium among women and in a baboon model of endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Nimesulide, a COX-2 inhibitor, does not reduce lesion size or number in a nude mouse model of endometriosis.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Endometrial-peritoneal interactions during endometriotic lesion establishment

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Anti-TNF-alpha treatment for deep endometriosis-associated pain: a randomized placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Gene expression profiling of the rat endometriosis model

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Size and spatial orientation of uterine tissue transplants on the peritoneum crucially determine the growth and cyst formation of endometriosis-like lesions in mice

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

DNA microarray analysis in a mouse model for endometriosis and validation of candidate factors with human adenomyosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

In vitro and in vivo approaches to study angiogenesis in the pathophysiology and therapy of endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Selective cyclo-oxygenase-2 inhibition induces regression of autologous endometrial grafts by down-regulation of vascular endothelial growth factor-mediated angiogenesis and stimulation of caspase-3-dependent apoptosis.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

High-resolution ultrasound imaging: a novel technique for the noninvasive in vivo analysis of endometriotic lesion and cyst formation in small animal models

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Clinical attrition due to biased preclinical assessments of potential efficacy.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Improved nude mouse models for green fluorescence human endometriosis.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis with an antiangiogenic effect in a rat model

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Good laboratory practice: preventing introduction of bias at the bench

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Endometriosis-induced vaginal hyperalgesia in the rat: role of the ectopic growths and their innervation

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Endometriosis in patients with chronic pelvic pain: is staging predictive of the efficacy of laparoscopic surgery in pain relief?

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Influence of endometriosis on visceromotor and cardiovascular responses induced by vaginal distention in the rat.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Fenofibrate causes regression of endometriotic implants: a rat model.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis xenografts via antiangiogenic activity in severe combined immunodeficiency mice.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Animal models and the prediction of efficacy in clinical trials of analgesic drugs: a critical appraisal and call for uniform reporting standards

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Priorities for endometriosis research: recommendations from an international consensus workshop.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Publication bias in reports of animal stroke studies leads to major overstatement of efficacy

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Treatment of endometriosis-related pain: options and outcomes

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Return of chronic pelvic pain from endometriosis after raloxifene treatment: a randomized controlled trial

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

High density of small nerve fibres in the functional layer of the endometrium in women with endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Different types of small nerve fibers in eutopic endometrium and myometrium in women with endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Tumor necrosis factor antagonist mechanisms of action: a comprehensive review

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Can animal models of disease reliably inform human studies?

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Endometriosis: current therapies and new pharmacological developments.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

'Waiting for Godot': a commonsense approach to the medical treatment of endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Rich innervation of deep infiltrating endometriosis

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Anti-angiogenic effects of green tea catechin on an experimental endometriosis mouse model.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Etanercept causes regression of endometriotic implants in a rat model.

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Association between endometriosis stage, lesion type, patient characteristics and severity of pelvic pain symptoms: a multivariate analysis of over 1000 patients

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMR030

21 January 2018

Identifiers

10.1093/HUMUPD/DMR030

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21733981%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21733981%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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