(Q37902873)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

review article

5 references

2 August 2020

8 September 2020

8 February 2021

22 August 2022

Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

3 April 2019

pharmaceutical preparation

1 reference

biomedical investigative technique

6 August 2019

1 reference

19 September 2019

1 reference

2 August 2020

investigational drugs

1 reference

8 September 2020

1 reference

8 February 2021

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Lucinda J. Billingham

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Ranald I. Mackay

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Ian Stratford

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

K J Harrington

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

T B Brunner

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

N G Burnet

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

C S Chan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

P Hoskin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

T S Maughan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

J Macdougall

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

W G McKenna

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

C M Nutting

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

A Oliver

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

R Plummer

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

English

0 references

publication date

19 July 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Cancer

8 February 2020

23 August 2011

4 references

2 August 2020

8 September 2020

8 February 2021

22 August 2022

8 references

3 April 2019

6 August 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

2 August 2020

8 September 2020

8 February 2021

22 August 2022

105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

628-639

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/bjc.2011.240

8 February 2020

exact match

0 references

cites work

Effects of lapatinib monotherapy: results of a randomised phase II study in therapy-naive patients with locally advanced squamous cell carcinoma of the head and neck

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Characterization of image quality and image-guidance performance of a preclinical microirradiator

6 September 2017

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How genetically engineered mouse tumor models provide insights into human cancers

6 September 2017

1 reference

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Diffusion MR imaging for monitoring of treatment response

6 September 2017

1 reference

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Targeted therapies in soft tissue sarcomas

6 September 2017

1 reference

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Stereotactic body radiation therapy: the report of AAPM Task Group 101.

6 September 2017

1 reference

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Cancer Response Criteria and Bone Metastases: RECIST 1.1, MDA and PERCIST.

6 September 2017

1 reference

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Use of γH2AX and other biomarkers of double-strand breaks during radiotherapy

6 September 2017

1 reference

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DNA repair targeting and radiotherapy: a focus on the therapeutic ratio

6 September 2017

1 reference

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An Orthotopic Lung Tumor Model for Image-Guided Microirradiation in Rats

6 September 2017

1 reference

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A Review of the Clinical Evidence for Intensity-modulated Radiotherapy

6 September 2017

1 reference

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In vivo bioluminescent imaging of irradiated orthotopic pancreatic cancer xenografts in nonobese diabetic-severe combined immunodeficient mice: a novel method for targeting and assaying efficacy of ionizing radiation

6 September 2017

1 reference

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Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair.

6 September 2017

1 reference

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Radiation-induced cell death mechanisms

6 September 2017

1 reference

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Recent advances in radiotherapy

6 September 2017

1 reference

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Recent advances in combined modality therapy

6 September 2017

1 reference

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An overview of the optimal planning, design, and conduct of phase I studies of new therapeutics

6 September 2017

1 reference

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Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma

6 September 2017

1 reference

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Novel therapeutics in combination with radiotherapy to improve cancer treatment: rationale, mechanisms of action and clinical perspective

6 September 2017

1 reference

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Effectiveness of combined modality radiotherapy of orthotopic human squamous cell carcinomas in Nu/Nu mice using cetuximab, tirapazamine and MnSOD-plasmid liposome gene therapy

6 September 2017

1 reference

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Biomarker-driven early clinical trials in oncology: a paradigm shift in drug development

6 September 2017

1 reference

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Clinical radiation sensitivity with DNA repair disorders: an overview

6 September 2017

1 reference

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Systemic effects of local radiotherapy

6 September 2017

1 reference

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Novel targeted radiosensitisers in cancer treatment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Physicochemical drug properties associated with in vivo toxicological outcomes: a review

6 September 2017

1 reference

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EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma

6 September 2017

1 reference

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The current status of drug discovery against the human kinome

6 September 2017

1 reference

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

6 September 2017

1 reference

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Identity tests: determination of cell line cross-contamination

6 September 2017

1 reference

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Total body irradiation before an allogeneic stem cell transplantation: is there a magic dose?

6 September 2017

1 reference

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Use of a modified hemi-body irradiation technique for metastatic carcinoma of the prostate: report of a 10-year experience.

6 September 2017

1 reference

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Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis

6 September 2017

1 reference

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DNA repair pathways as targets for cancer therapy

6 September 2017

1 reference

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Enhanced in vitro and in vivo cytotoxicity of combined reovirus and radiotherapy

6 September 2017

1 reference

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Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library

6 September 2017

1 reference

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Evaluation of early and late toxicities in chemoradiation trials.

6 September 2017

1 reference

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Molecular biology for the radiation oncologist: the 5Rs of radiobiology meet the hallmarks of cancer

6 September 2017

1 reference

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Innovation in the management of brain metastases.

6 September 2017

1 reference

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Effects of prolongation of overall treatment time due to unplanned interruptions during radiotherapy of different tumor sites and practical methods for compensation

6 September 2017

1 reference

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Exploitable mechanisms for combining drugs with radiation: concepts, achievements and future directions

6 September 2017

1 reference

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The role of external beam radiotherapy in the management of bone metastases

6 September 2017

1 reference

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Palliative radiotherapy regimens for non-small cell lung cancer

6 September 2017

1 reference

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Isobologram analysis of triple therapies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC): a meta-analysis of individual data from 1764 patients.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Recent advances in multimodal treatment for gastric cancer: a review

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Approaches for the sequence-specific knockdown of mRNA.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

The contemporary drug development process: advances and challenges in preclinical and clinical development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

The calculation of microbial assays

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

The opportunities and challenges of personalized genome-based molecular therapies for cancer: targets, technologies, and molecular chaperones

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

A meta-analysis of randomized controlled trials that compared neoadjuvant chemoradiation and surgery to surgery alone for resectable esophageal cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

How much gets there and what does it do?: The need for better pharmacokinetic and pharmacodynamic endpoints in contemporary drug discovery and development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Use of isogenic human cancer cells for high-throughput screening and drug discovery

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Survival and recurrence after concomitant chemotherapy and radiotherapy for cancer of the uterine cervix: a systematic review and meta-analysis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Short tandem repeat profiling provides an international reference standard for human cell lines

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

6 September 2017

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

New colorimetric cytotoxicity assay for anticancer-drug screening

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Identification of essential genes in cultured mammalian cells using small interfering RNAs.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Exploitable mechanisms in combined radiotherapy-chemotherapy: The concept of additivity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Quantitative analysis of radiation-induced DNA break repair in a cultured oral mucosal model.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Response of xenografts of human malignant gliomas and squamous cell carcinomas to fractionated irradiation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

γ-H2AX detection in peripheral blood lymphocytes, splenocytes, bone marrow, xenografts, and skin.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Envisioning the future of early anticancer drug development.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Phase I study of lapatinib in combination with chemoradiation in patients with locally advanced squamous cell carcinoma of the head and neck

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Phase I study of oxaliplatin, full-dose gemcitabine, and concurrent radiation therapy in pancreatic cancer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

TNF-alpha gene and proton radiotherapy in an orthotopic brain tumor model.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Adaptive dose finding for phase I clinical trials of drugs used for chemotherapy of cancer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Characterization of the DNA double strand break repair defect in scid mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Postoperative Concurrent Radiotherapy and Chemotherapy for High-Risk Squamous-Cell Carcinoma of the Head and Neck

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188925

Phase I and pharmacokinetic study of YM155, a small-molecule inhibitor of survivin.

1 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FBJC.2011.240

UKCCCR guidelines for the use of cell lines in cancer research

21 January 2018

1 reference

12 December 2020

Heterotransplantation of a human malignant tumour to "Nude" mice

1 reference

12 December 2020

Intestinal Crypt Survival and Total and Per Crypt Levels of Proliferative Cellularity Following Irradiation: Fractionated X-Ray Exposures

1 reference

12 December 2020

Intestinal Crypt Survival and Total and Per Crypt Levels of Proliferative Cellularity Following Irradiation: Single X-Ray Exposures

1 reference

12 December 2020

A phase I study of dose-escalated chemoradiation with accelerated intensity modulated radiotherapy in locally advanced head and neck cancer

1 reference

12 December 2020

Radiotherapy Research Priorities for the UK

1 reference

12 December 2020

Radiation-induced oral mucositis in mice: strain differences

1 reference

12 December 2020

The enhanced sensitivity of mammalian cells to killing by X rays after prolonged exposure to several nitroimidazoles

1 reference

12 December 2020

Metronidazole: Effect on Radiosensitivity of Tumor and Normal Tissues in Mice2

1 reference

12 December 2020

Intensity Modulated Radiotherapy (IMRT) in locally advanced thyroid cancer: acute toxicity results of a phase I study

1 reference

12 December 2020

Modification of Hypoxia-Induced Radioresistance in Tumors by the Use of Oxygen and Sensitizers

1 reference

12 December 2020

Update on palliative radiotherapy endpoints for bone metastasis trials

1 reference

12 December 2020

SOME CHARACTERISTICS OF THE SURVIVAL CURVE OF CRYPT CELLS OF THE SMALL INTESTINE OF THE MOUSE DEDUCED AFTER WHOLE BODY X IRRADIATION

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.2011.240

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

21772330

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21772330%20AND%20SRC:MED&resulttype=core&format=json