(Q37913125)

25 August 2017

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title

Ocular drug delivery. Pharmacokinetic considerations (English)

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25 August 2017

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Schoenwald RD

1

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25 August 2017

1 April 1990

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Clinical Pharmacokinetics

25 August 2017

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25 August 2017

18

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25 August 2017

4

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25 August 2017

255-269

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https://scigraph.springernature.com/pub.10.2165/00003088-199018040-00001

25 August 2017

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cites work

Dipivalyl epinephrine: a new pro-drug in the treatment of glaucoma

1 reference

12 December 2020

Ocular pharmacology of sulfonamides: the cornea as barrier and depot

1 reference

12 December 2020

Ethoxzolamide analogue gel. A topical carbonic anhydrase inhibitor

1 reference

12 December 2020

Intraocular penetration of topically applied lincomycin hydrochloride in rabbits

1 reference

12 December 2020

Pharmacokinetics and tissue penetration of ceftazidime: studies on lymph, aqueous humour, skin blister, cerebrospinal and pleural fluid

1 reference

12 December 2020

Disposition of cyclophosphamide in the rabbit and human cornea.

1 reference

12 December 2020

Aqueous vs viscous phenylephrine. I. Systemic absorption and cardiovascular effects.

1 reference

12 December 2020

Permeability of Human Cornea and Sclera to Sulfonamide Carbonic Anhydrase Inhibitors

1 reference

12 December 2020

Pilocarpic acid esters as novel sequentially labile pilocarpine prodrugs for improved ocular delivery.

1 reference

12 December 2020

Topical fluorouracil. Pharmacokinetics in normal rabbit eyes

1 reference

12 December 2020

Ocular disposition of topically applied histamine, cimetidine, and pyrilamine in the albino rabbit

1 reference

12 December 2020

Mechanistic and Quantitative Evaluation of Precorneal Pilocarpine Disposition in Albino Rabbits

1 reference

12 December 2020

Topical ocular drug delivery: recent developments and future challenges

1 reference

12 December 2020

Corneal Penetration Behavior of β-Blocking Agents I: Physicochemical Factors

1 reference

12 December 2020

Vehicle Effects on Ocular Drug Bioavailability I: Evaluation of Fluorometholone

1 reference

12 December 2020

Studies on rabbit corneal permeability of local anesthetics (I).

1 reference

12 December 2020

Effect of phenylephrine on aqueous humor flow

1 reference

12 December 2020

Preliminary Pharmacokinetic Model of Pilocarpine Uptake and Distribution in the Eye

1 reference

12 December 2020

Disposition of topical flurbiprofen in normal and aphakic rabbit eyes

1 reference

12 December 2020

Reduction of phenylephrine drop size in infants achieves equal dilation with decreased systemic absorption

1 reference

12 December 2020

Mechanisms of corneal drug penetration. I: In vivo and in vitro kinetics

1 reference

12 December 2020

Pharmacokinetics and metabolism of 5-fluorouracil following subconjunctival versus intravenous administration

1 reference

12 December 2020

Ocular pharmacokinetic models of clonidine-3H hydrochloride.

1 reference

12 December 2020

Cefsulodin concentrations in rabbit eyes after intravenous and subconjunctival administration

1 reference

12 December 2020

Topical carbonic anhydrase inhibitors

1 reference

12 December 2020

Topically applied oxymetazoline. Ocular vasoconstrictive activity, pharmacokinetics, and metabolism

1 reference

12 December 2020

Ocular esterase composition in albino and pigmented rabbits: possible implications in ocular prodrug design and evaluation

1 reference

12 December 2020

Ocular and systemic bioavailability of ophthalmic flurbiprofen

1 reference

12 December 2020

Soft drugs: principles and methods for the design of safe drugs

1 reference

12 December 2020

Aqueous chamber drug distribution volume measurement in rabbits

1 reference

12 December 2020

Penetration routes of topically applied eye medications

1 reference

12 December 2020

The transcorneal permeability of sulfonamide carbonic anhydrase inhibitors and their effect on aqueous humor secretion

1 reference

12 December 2020

On the pharmacology of L-645,151: a topically effective ocular hypotensive carbonic anhydrase inhibitor

1 reference

12 December 2020

Corneal Penetration Behavior of β-Blocking Agents II: Assessment of Barrier Contributions

1 reference

12 December 2020

New methods of measuring the rate of aqueous flow in man with fluorescein

1 reference

12 December 2020

In vivo comparison of phenylephrine and phenylephrine oxazolidine instilled in the monkey eye

1 reference

12 December 2020

Fluorophotometric measurement of human tear turnover rate

1 reference

12 December 2020

Corneal drug absorption: An Illustration of Parallel First‐Order Absorption and Rapid Loss of Drug from Absorption Depot

1 reference

12 December 2020

Aqueous humor penetration of ciprofloxacin in the human eye.

1 reference

12 December 2020

Quantitative precorneal disposition of topically applied pilocarpine nitrate in rabbit eyes

1 reference

12 December 2020

Structures and fluids involved in the penetration of topically applied drugs.

1 reference

12 December 2020

Pharmacokinetics of the antineoplastic agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in the aqueous and vitreous of rabbit

1 reference

12 December 2020

Improving the therapeutic index of topical phenylephrine by reducing drop volume

1 reference

12 December 2020

[Ocular penetration of topical diclofenac sodium, a non-steroidal anti-inflammatory drug, in rabbit eye]

1 reference

12 December 2020

Ocular pharmacology of methazolamide analogs: distribution in the eye and effects on pressure after topical application.

1 reference

12 December 2020

Importance of the noncorneal absorption route in topical ophthalmic drug delivery

1 reference

12 December 2020

Pharmacokinetics of fluorescein in the vitreous

1 reference

12 December 2020

Improving the ocular absorption of phenylephrine

1 reference

12 December 2020

Drop Size and Initial Dosing Frequency Problems of Topically Applied Ophthalmic Drugs

1 reference

12 December 2020

Distribution of salicylate in lens and intraocular fluids and its effect on cataract formation

1 reference

12 December 2020

Ocular pharmacokinetics of subconjunctivally versus intravenously administered 6-mercaptopurine

1 reference

12 December 2020

Improved corneal penetration of timolol by prodrugs as a means to reduce systemic drug load

1 reference

12 December 2020

Thienothiopyran-2-sulfonamides: a novel class of water-soluble carbonic anhydrase inhibitors

1 reference

12 December 2020

Topical carbonic anhydrase inhibitors. III: Optimization model for corneal penetration of ethoxzolamide analogues.

1 reference

12 December 2020

Carbonic anhydrase: chemistry, physiology, and inhibition

1 reference

12 December 2020

Pharmacokinetics and safety of transcorneal iontophoresis of tobramycin in the rabbit

1 reference

12 December 2020

Relationship between steroid permeability across excised rabbit cornea and octanol-water partition coefficients

1 reference

12 December 2020

Use of dilute drug solutions for routine cycloplegia and mydriasis

1 reference

12 December 2020

Corneal penetration and ocular bioavailability of drugs

1 reference

12 December 2020

Effect of Parallel First-Order Drug Loss from Site of Administration on Calculated Values for Absorption Rate Constants

1 reference

12 December 2020

Decrease in intraocular pressure in man by a carbonic anhydrase inhibitor, diamox; a preliminary report

1 reference

12 December 2020

Ocular distribution studies of the topical carbonic anhydrase inhibitors L-643,799 and L-650,719 and related alkyl prodrugs

1 reference

12 December 2020

Mechanistic Studies on Transcorneal Permeation of Fluorometholone

1 reference

12 December 2020

Topical treatment of experimental herpes simplex keratouveitis with 2'-O-glycylacyclovir. A water-soluble ester of acyclovir

1 reference

12 December 2020

Systemic side effects from ophthalmic timolol and their prevention

1 reference

12 December 2020

The pharmacokinetics of ocularly applied timolol in rabbits

1 reference

12 December 2020

Physicochemical determinants of drug diffusion across the conjunctiva, sclera, and cornea.

1 reference

12 December 2020

Pharmacokinetics of aztreonam in rabbit eyes

1 reference

12 December 2020

Penetration of topically administered prednisolone acetate into the human aqueous humor

1 reference

12 December 2020

The permeability of the corneal endothelium to fluorescein in the normal human eye

1 reference

12 December 2020

Lacrimal and Instilled Fluid Dynamics in Rabbit Eyes

1 reference

12 December 2020

Treatment of glaucoma using minidrops of clonidine

1 reference

12 December 2020

N-Substituted sulfonamide carbonic anhydrase inhibitors with topical effects on intraocular pressure

1 reference

12 December 2020

Ophthalmic bioequivalence of steroid/antibiotic combination formulations

1 reference

12 December 2020

A physiologically based pharmacokinetic model for the intraocular distribution of pilocarpine in rabbits

1 reference

12 December 2020

Ocular absorption and disposition of phenylephrine and phenylephrine oxazolidine

1 reference

12 December 2020

The ocular pharmacokinetics of eicosanoids and their derivatives. 1. Comparison of ocular eicosanoid penetration and distribution following the topical application of PGF2 alpha, PGF2 alpha-1-methyl ester, and PGF2 alpha-1-isopropyl ester

1 reference

12 December 2020

The effect of azone on ocular levobunolol absorption: calculating the area under the curve and its standard error using tissue sampling compartments

1 reference

12 December 2020

The nonenzymatic displacement of the sulfamoyl group from different classes of aromatic compounds by glutathione and cysteine

1 reference

12 December 2020

Ocular pharmacokinetics of dapiprazole

1 reference

12 December 2020

Intraocular levels of cefamandole compared with cefazolin after subconjunctival injection in rabbits

1 reference

12 December 2020

Pharmacokinetics of instilled drugs in the human eye.

1 reference

12 December 2020

Bioavailability and corneal anti-inflammatory effect of topical suprofen

1 reference

12 December 2020

Corneal and intraocular penetration of topical and subconjunctival fusidic acid

1 reference

12 December 2020

Pharmacokinetics of Topically Applied Pilocarpine in the Albino Rabbit Eye

1 reference

12 December 2020

Evaluation of Drugs in Ointment for Mydriasis and Cycloplegia

1 reference

12 December 2020

Ocular absorption and metabolism of topically applied epinephrine and a dipivalyl ester of epinephrine

1 reference

12 December 2020

Ocular disposition of aminozolamide in the rabbit eye

1 reference

12 December 2020

Pharmacokinetics of topically applied ophthalmic drugs

1 reference

12 December 2020

10.2165/00003088-199018040-00001

Identifiers

DOI

1 reference

PubMed ID

2182264

Dimensions Publication ID

25 August 2017

0 references

1 reference

PubMed ID

2182264