(Q37917628)

25 August 2017

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title

Carrier-mediated transport in the hepatic distribution and elimination of drugs, with special reference to the category of organic cations (English)

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25 August 2017

D K Meijer

1

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25 August 2017

W E Mol

series ordinal

2

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25 August 2017

M Müller

series ordinal

3

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25 August 2017

G Kurz

series ordinal

4

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25 August 2017

language of work or name

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1 February 1990

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Journal of Pharmacokinetics and Pharmacodynamics

25 August 2017

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25 August 2017

18

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25 August 2017

1

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25 August 2017

35-70

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https://scigraph.springernature.com/pub.10.1007/bf01063621

25 August 2017

0 references

cites work

Current concepts on hepatic transport of drugs

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Structure-pharmacokinetics relationship of quaternary ammonium compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Structure-pharmacokinetics relationship of quaternary ammonium compounds. Correlation of physicochemical and pharmacokinetic parameters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Molecular weight as a factor in the excretion of monoquaternary ammonium cations in the bile of the rat, rabbit and guinea pig

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Biliary excretion of some diquaternary ammonium cations in the rat, guinea pig and rabbit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Concentrative transfer of an organic cation from blood into bile.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Absorption and secretion of monoquaternary ammonium compounds by the isolated intestinal mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Localization of 14C-pancuronium by histo- and wholebody-autoradiography in normal and pregnant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

The cardiac glycoside sensitive step in the hepatic transport of the bisquaternary ammonium compound, hexafluorenium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Hepatic transport mechanisms for bivalent organic cations. Subcellular distribution and hepato-biliary concentration gradients of some steroidal muscle relaxants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Photoaffinity labels as pharmacological tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Metabolism of quaternary ammonium compounds. I. Binding of tropane alkaloids to rat liver lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

The effects of neuromuscular blocking agents on mitochondria. IV. Effects of d-tubocurarine, pyrrolizidine alkaloids and magnesium on oxidative phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Inhibition of ouabain-H3 uptake by liver slices and its excretion into the bile and by compounds having a steroid nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Interaction of fusidates with bile acid uptake by isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Properties of iodipamide uptake by isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

Transport of dibromosulphthalein by isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01063621

The pharmacology of atracurium: a new competitive neuromuscular blocking agent

21 January 2018

1 reference

12 December 2020

Curare-like agents: relation between lipid solubility and transport into bile in perfused rat liver

1 reference

12 December 2020

Iodipamide uptake by rat liver plasma membrane vesicles enriched in the sinusoidal fraction: evidence for a carrier-mediated transport dependent on membrane potential

1 reference

12 December 2020

Properties of (Na+ + K+)-activated ATPase in rat liver plasma membranes enriched with bile canaliculi

1 reference

12 December 2020

The neurotoxins 1-methyl-4-phenylpyridinium and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine are substrates for the organic cation transporter in renal brush border membrane vesicles.

1 reference

12 December 2020

Some properties of the thiamine uptake system in isolated rat hepatocytes

1 reference

12 December 2020

Functional reconstitution of the canalicular bile salt transport system of rat liver

1 reference

12 December 2020

The excretion of hexafluorenium in man and rat

1 reference

12 December 2020

Clinical pharmacokinetics of the non-depolarising muscle relaxants

1 reference

12 December 2020

A carrier-mediated transport system for benzylpenicillin in isolated hepatocytes

1 reference

12 December 2020

Influence of Cl- on organic anion transport in short-term cultured rat hepatocytes and isolated perfused rat liver

1 reference

12 December 2020

Conversion of biomembrane-produced energy into electric form. II. Intact mitochondria

1 reference

12 December 2020

Taurocholate transport by rat liver sinusoidal membrane vesicles: evidence of sodium cotransport

1 reference

12 December 2020

Characterization of the anion transport system in hepatocyte plasma membranes

1 reference

12 December 2020

Characterization of the bile acid transport system in normal and transformed hepatocytes. Photoaffinity labeling of the taurocholate carrier protein.

1 reference

12 December 2020

The relation between structure and distribution of quaternary ammonium ions in mice and rats. Simple tetraalkylammonium and a series of m-substituted trimethylphenylammonium ions

1 reference

12 December 2020

Hepatic uptake and biliary excretion of d-tubocurarine and trimethyltubocurarine in the rat in vivo and in isolated perfused rat livers

1 reference

12 December 2020

The Fate of Pancuronium Bromide in Man

1 reference

12 December 2020

Na-H exchange in rat liver basolateral but not canalicular plasma membrane vesicles

1 reference

12 December 2020

Mechanisms of taurocholate transport in canalicular and basolateral rat liver plasma membrane vesicles. Evidence for an electrogenic canalicular organic anion carrier

1 reference

12 December 2020

The quinidine-digoxin interaction in perspective

1 reference

12 December 2020

The kinetics of sulfobromophthalein uptake by rat liver sinusoidal vesicles

1 reference

12 December 2020

Competitive inhibition of the uptake of demethylphalloin by cholic acid in isolated hepatocytes. Evidence for a transport competition rather than a binding competition

1 reference

12 December 2020

Further characterization of membrane proteins involved in the transport of organic anions in hepatocytes. Comparison of two different affinity labels: 4,4'-diisothiocyano-1,2-diphenylethane-2,2'-disulfonic acid and brominated taurodehydrocholic acid

1 reference

12 December 2020

A preliminary investigation of the renal and hepatic excretion of gallamine triethiodide in man

1 reference

12 December 2020

Localization of d-tubocurarine in rat liver lysosomes. Lysosomal uptake, biliary excretion and displacement by quinacrine in vivo

1 reference

12 December 2020

Uptake, accumulation and release of ouabain by isolated rat hepatocytes

1 reference

12 December 2020

Identity of hepatic membrane transport systems for bile salts, phalloidin, and antamanide by photoaffinity labeling

1 reference

12 December 2020

The pH gradient-dependent transport of organic cations in the renal brush border membrane. Studies with acridine orange

1 reference

12 December 2020

Physicochemical and immunohistological studies of a sulfobromophthalein- and bilirubin-binding protein from rat liver plasma membranes

1 reference

12 December 2020

Disposition of pipecurium bromide in rats

1 reference

12 December 2020

New intravenous anaesthetics and neuromuscular blocking drugs. A review of their properties and clinical use.

1 reference

12 December 2020

Identification, purification, and partial characterization of an organic anion binding protein from rat liver cell plasma membrane

1 reference

12 December 2020

Identification of different transport systems for bile salts in sinusoidal and canalicular membranes of hepatocytes

1 reference

12 December 2020

Photoaffinity labeling of whole cells by flashed light: a simple apparatus for high-energy ultraviolet flashes

1 reference

12 December 2020

Cholestatic steroid hormones inhibit taurocholate uptake into isolated rat hepatocytes

1 reference

12 December 2020

Autoradiographic Studies on the Distribution of Quaternary Ammonium Compounds. II. Distribution of <SUP>1</SUP>4C-Labeled Decamethonium, Hexamethonium and Dimethonium in Mice

1 reference

12 December 2020

Vesicular uptake system for the cation lucigenin in the rat hepatocyte.

1 reference

12 December 2020

Kinetics of the elimination and neuromuscular blocking effect of d-tubocurarine in man.

1 reference

12 December 2020

Protective effect of anionic cholecystographic agents against phalloidin on isolated hepatocytes by competitive inhibition of the phallotoxin uptake. Comparison of the influence on the inward transport of 3H-demethylphalloin and of 14C-cholate

1 reference

12 December 2020

Driving forces in hepatocellular uptake of phalloidin and cholate

1 reference

12 December 2020

Pharmacokinetics of diallyl-nor-toxiferine in man

1 reference

12 December 2020

Uptake of quaternary ammonium compounds into rat liver plasma membrane vesicles

1 reference

12 December 2020

Uptake of Taurocholic Acid into Isolated Rat-Liver Cells

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12 December 2020

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue

1 reference

12 December 2020

Uptake of estrone, estradiol-17beta and testosterone by isolated rat liver cells

1 reference

12 December 2020

Acinar redistribution and heterogeneity in transport of the organic cation rhodamine B in rat liver

1 reference

12 December 2020

On the localisation of d-tubocurarine in rat liver lysosomes in vivo by electron microscopy and subcellular fractionation

1 reference

12 December 2020

Hepatobiliary disposition of vecuronium bromide in man

1 reference

12 December 2020

Regulation of transmembrane electrical potential gradient in rat hepatocytes in situ.

1 reference

12 December 2020

Two systems are involved in the sulfobromophthalein uptake by rat liver cells: One is shared with bile salts

1 reference

12 December 2020

Effect of acute renal failure on the disposition and elimination of [3H]N-acetyl procainamide ethobromide in the rat

1 reference

12 December 2020

Bile acid transport in cultured rat hepatocytes

1 reference

12 December 2020

Further studies on bilitranslocase, a plasma membrane protein involved in hepatic organic anion uptake

1 reference

12 December 2020

Choleresis and hepatic transport mechanisms. IV. Influence of bile salt choleresis on the hepatic transport of the organic cations, D-tubocurarine and N4 -acetyl procainamide ethobromide

1 reference

12 December 2020

Unequal disposition of enantiomers of the organic cation oxyphenonium in the rat isolated perfused liver

1 reference

12 December 2020

Pharmacokinetics in Intravenous Anaesthetic Practice

1 reference

12 December 2020

Sodium ion-coupled uptake of taurocholate by rat-liver plasma membrane vesicles

1 reference

12 December 2020

A Scanning Electron Microscopic Study on Endothelial Cells and Kupffer Cells in Rat Liver Sinusoids

1 reference

12 December 2020

The lack of active bile acid transport in AS-30 D ascites hepatoma cells

1 reference

12 December 2020

Induction and inhibition of pinocytosis by aminoglycoside antibiotics

1 reference

12 December 2020

Role of plasma membrane ligand-binding proteins in the hepatocellular uptake of albumin-bound organic anions.

1 reference

12 December 2020

Hepatic disposition and biliary excretion of the organic cations thiazinamium and thiazinamium sulfoxide in rats

1 reference

12 December 2020

Uptake of rifampicin by isolated rat liver cells. Interaction with sulfobromophthalein uptake and evidence for separate carriers

1 reference

12 December 2020

Purification and reconstitution of the bile acid transport system from hepatocyte sinusoidal plasma membranes

1 reference

12 December 2020

Pharmacokinetics and disposition of pipecuronium bromide in the cat

1 reference

12 December 2020

The interaction of hepatocyte plasma membranes with an azide derivative of procaine

1 reference

12 December 2020

Identification of cyclosporin binding sites in rat liver plasma membranes, isolated hepatocytes, and hepatoma cells by photoaffinity labeling using [3H]cyclosporin-diaziridine

1 reference

12 December 2020

The function of Gp170, the multidrug resistance gene product, in rat liver canalicular membrane vesicles.

1 reference

12 December 2020

Mechanisms of bile formation, hepatic uptake, and biliary excretion.

1 reference

12 December 2020

Distribution and kinetics of 14C-vecuronium in rats and mice.

1 reference

12 December 2020

Isolation and partial characterization of a fatty acid binding protein in rat liver plasma membranes

1 reference

12 December 2020

Mechanisms underlying the prolonged duration of action of muscle relaxants caused by extrahepatic cholestasis

1 reference

12 December 2020

Hepatic uptake and biliary excretion of organic cations--I. Characterization of three new model compounds

1 reference

12 December 2020

Effect of organic anions on bile acid uptake by isolated rat hepatocytes

1 reference

12 December 2020

Common properties of hepatocellular uptake of cholate, iodipamide and antamanide, as distinct from the uptake of bromosulfophthalein

1 reference

12 December 2020

3′-Isothiocyanatobenzamido[3H]cholate, a new affinity label for hepatocellular membrane proteins responsible for the uptake of both bile acids and phalloidin

1 reference

12 December 2020

Hepatic drug transport in the rat. A comparison between isolated hepatocytes, the isolated perfused liver and the liver in vivo

1 reference

12 December 2020

Role of chloride on carrier-mediated transport of p-aminohippurate in rat renal basolateral membrane vesicles

1 reference

12 December 2020

Uptake of morphine and nalorphine by isolated rat hepatocytes

1 reference

12 December 2020

Bile-salt-binding polypeptides in plasma membranes of hepatocytes revealed by photoaffinity labelling

1 reference

12 December 2020

Hepatic uptake and biliary excretion of organic cations--II. The influence of ion pair formation

1 reference

12 December 2020

Disposition kinetics of pancuronium bromide in patients with total biliary obstruction

1 reference

12 December 2020

Carrier-mediated transport of ouabain in isolated hepatocytes

1 reference

12 December 2020

Active transport of quaternary ammonium compounds into bile.

1 reference

12 December 2020

The influence of various bile salts and some cholephilic dyes on Na+, K+- and Mg2+-activated ATPase of rat liver in relation to cholestatic effects

1 reference

12 December 2020

alpha-Amanitin uptake into hepatocytes. Identification of hepatic membrane transport systems used by amatoxins

1 reference

12 December 2020

Direct determination of the driving forces for taurocholate uptake into rat liver plasma membrane vesicles

1 reference

12 December 2020

The relationship between disposition and duration of action of congeneric series of steroidal neuromuscular blocking agents

1 reference

12 December 2020

Pharmacokinetics and disposition of chandonium iodide in rat.

1 reference

12 December 2020

Biopharmaceutical study of the hepato-biliary transport of drugs. V. Hepatic uptake and biliary excretion of organic cations

1 reference

12 December 2020

Reconstitution in vitro of sulfobromophthalein transport by bilitranslocase

1 reference

12 December 2020

Comparative pharmacokinetics and dynamics of vecuronium and pancuronium in anesthetized patients.

1 reference

12 December 2020

Influence of renal and hepatic function on pharmacodynamics and pharmacokinetics of non-depolarizing muscle relaxants

1 reference

12 December 2020

Ionic requirements for taurocholate transport in rat liver plasma membrane vesicles

1 reference

12 December 2020

Distribution of quaternary ammonium compounds between particulate and soluble constituents of rat liver, in relation to their transport from plasma into bile

1 reference

12 December 2020

Modified somatostatins as inhibitors of a multispecific transport system for bile acids and phallotoxins in isolated hepatocytes

1 reference

12 December 2020

Involvement of nucleophiles in the inactivation of atracurium

1 reference

12 December 2020

Multispecific anion exchange in basolateral (sinusoidal) rat liver plasma membrane vesicles

1 reference

12 December 2020

Transport rates of hepatic uptake and biliary excretion of an organic cation, acetyl procainamide ethobromide

1 reference

12 December 2020

Biliary excretion of nicotinamide riboside. A possible role in the regulation of hepatic pyridine nucleotide dynamics

1 reference

12 December 2020

Comparative Pharmacokinetics of d-Tubocurarine and Metocurine in Man

1 reference

12 December 2020

Hepatocellular uptake of sulfobromophthalein and bilirubin is selectively inhibited by an antibody to the liver plasma membrane sulfobromophthalein/bilirubin binding protein

1 reference

12 December 2020

Identification of the hepatocyte Na+-dependent bile acid transport protein using monoclonal antibodies.

1 reference

12 December 2020

Uptake and excretion of the quaternary ammonium compound deptropine methiodide in the isolated perfused rat liver

1 reference

12 December 2020

Uptake of estrone sulfate by isolated rat liver cells

1 reference

12 December 2020

Autoradiographic studies on the distribution of quaternary ammonium compounds. III. Distribution, excretion and metabolism of 14C-labeled pancuronium bromide in rats

1 reference

12 December 2020

Metabolic fate of the short-acting peripheral neuromuscular blocking agent stercuronium in the rat, as related to its action

1 reference

12 December 2020

Transport functions of the liver. Lack of correlation between hepatocellular ouabain uptake and binding to (Na+ + K+)-ATPase.

1 reference

12 December 2020

Cell membrane potential and resistance in liver.

1 reference

12 December 2020

Effects of hepatic uptake of vecuronium bromide and its putative metabolites on their neuromuscular blocking actions in the cat

1 reference

12 December 2020

Hepatic disposition of cationic drugs bound to asialoorosomucoid: lack of coendocytosis and evidence for intrahepatic dissociation

1 reference

12 December 2020

Binding of d-tubocurarine di (methyl-14C) ether iodide and other amines to cartilage, chondroitin sulfate and human plasma proteins

1 reference

12 December 2020

Hepatic transport of mono and bisquaternary ammonium compounds

1 reference

12 December 2020

Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

1 reference

12 December 2020

The comparative potency and pharmacokinetics of pancuronium and its metabolites in anesthetized man

1 reference

12 December 2020

Renal tubule transport of organic cations

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12 December 2020

Isolation of an organic anion binding protein from rat liver plasma membrane fractions by affinity chromatography

1 reference

12 December 2020

Carrier-mediated transport of the organic cation procaine amide ethobromide by isolated rat liver parenchymal cells

1 reference

12 December 2020

Uptake of cortisol by isolated rat liver cells. A phenomenon indicative of carrier-mediation and simple diffusion

1 reference

12 December 2020

Renal and biliary elimination of vecuronium (ORG NC 45) and pancuronium in rats

1 reference

12 December 2020

The Metabolism and Elimination of d-Tubocurarine-H3

1 reference

12 December 2020

Hepatic transport of organic cations: active uptake of a quaternary ammonium compound, procaine amide ethobromide. by rat liver slices

1 reference

12 December 2020

Isolation and characterization of the putative canalicular bile salt transport system of rat liver

1 reference

12 December 2020

Immunological studies of an organic anion-binding protein isolated from rat liver cell plasma membrane

1 reference

12 December 2020

Effect of Na on bile acid uptake by isolated rat hepatocytes. Evidence for a heterogeneous system

1 reference

12 December 2020

Evidence for carrier-mediated chloride/bicarbonate exchange in canalicular rat liver plasma membrane vesicles

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12 December 2020

Transport systems of isolated hepatocytes. Studies on the transport of biliary compounds

1 reference

12 December 2020

Transport of drugs in isolated hepatocytes the influence of bile salts

1 reference

12 December 2020

Inhibition of Taurocholate and Ouabain Transport in Isolated Rat Hepatocytes by Cyclosporin A

1 reference

12 December 2020

Pharmacokinetic study on saturated hepato-biliary transport of acetyl procainamide ethobromide

1 reference

12 December 2020

Hydroxyl/bile acid exchange. A new mechanism for the uphill transport of cholate by basolateral liver plasma membrane vesicles

1 reference

12 December 2020

Hepatic uptake and biliary excretion of N-acetyl procaine amide ethobromide in the rat.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01063621

1 reference

25 August 2017

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