(Q37932057)

25 August 2017

Hepatocellular carcinoma in non-alcoholic steatohepatitis: Growing evidence of an epidemic? (English)

1 reference

non-alcoholic steatohepatitis

25 August 2017

0 references

1 reference

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

1 reference

Etsuko Hashimoto

1

1 reference

PubMed ID

21917086

25 August 2017

Katsutoshi Tokushige

series ordinal

2

1 reference

25 August 2017

15 September 2011

1 reference

25 August 2017

1 reference

25 August 2017

42

1 reference

25 August 2017

1

1 reference

25 August 2017

1-14

1 reference

Primary liver cancer: worldwide incidence and trends

25 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Hepatocellular carcinoma: epidemiology, risk factors, and screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Hepatocellular carcinoma in the Asia pacific region

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Epidemiology of hepatocellular carcinoma in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Hepatitis C virus infection, age, and Hispanic ethnicity increase mortality from liver cancer in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Metabolic syndrome and hepatocellular carcinoma: two growing epidemics with a potential link

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Epidemiology and natural history of NAFLD and NASH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

The epidemiology of newly diagnosed chronic liver disease in gastroenterology practices in the United States: results from population-based surveillance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Prevalence of fatty liver in Japanese children and relationship to obesity. An epidemiological ultrasonographic survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Increase in the prevalence of fatty liver in Japan over the past 12 years: analysis of clinical background

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Etiology of liver cirrhosis in Japan: a nationwide survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Serum IL-6 levels and the risk for hepatocarcinogenesis in chronic hepatitis C patients: an analysis based on gender differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Prevalence, gender, ethnic variations, and prognosis of NASH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Clinical features and outcomes of cirrhosis due to non-alcoholic steatohepatitis compared with cirrhosis caused by chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Gender-specific differences in adipose distribution and adipocytokines influence adolescent nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Steatohepatitis: a tale of two "hits"?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Oxidative stress, KLF6 and transforming growth factor-beta up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

The contribution of endoplasmic reticulum stress to liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Autophagy in nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Liver disease in patients with diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Non-alcoholic steatohepatitis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Nonalcoholic steatohepatitis induced by a high-fat diet promotes diethylnitrosamine-initiated early hepatocarcinogenesis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Predictive power of biomarkers of oxidative stress and inflammation in patients with hepatitis C virus-associated hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Loss of function of retinoic acid in liver leads to steatohepatitis and liver tumor: A NASH animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

A central role for JNK in obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Beyond apoptosis of JNK1 in liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Apc(Δ716) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

mTOR regulation by JNK: rescuing the starving intestinal cancer cell?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

The mTOR pathway is associated with the poor prognosis of human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

The epidemiology of hepatocellular cancer: from the perspectives of public health problem to tumor biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Obesity and cancer risk: a Danish record-linkage study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

A prospective study of obesity and cancer risk (Sweden).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Effects of excess weight on cancer incidences depending on cancer sites and histologic findings among men: Korea National Health Insurance Corporation Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Impact of obesity on the surgical outcome following repeat hepatic resection in Japanese patients with recurrent hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Visceral fat accumulation is an independent risk factor for hepatocellular carcinoma recurrence after curative treatment in patients with suspected NASH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Excess risk of primary liver cancer in patients with diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Cancer incidence in a population-based cohort of patients hospitalized with diabetes mellitus in Denmark.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Role of diabetes mellitus in the etiology of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Antidiabetic therapy and increased risk of hepatocellular carcinoma in chronic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

The impact of obesity and diabetes mellitus on the risk of hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Iron overload is associated with hepatic oxidative damage to DNA in nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

HFE genotype, parenchymal iron accumulation, and liver fibrosis in patients with nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

The natural history of nonalcoholic fatty liver disease: a population-based cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Long-term follow-up of patients with NAFLD and elevated liver enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Long-term follow-up of patients with nonalcoholic fatty liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Decreased survival of subjects with elevated liver function tests during a 28-year follow-up.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Risk of cancer in patients hospitalized with fatty liver: a Danish cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Non-alcoholic steatohepatitis: a common cause of progressive chronic liver injury?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Long-term outcomes of cirrhosis in nonalcoholic steatohepatitis compared with hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

The incidence and risk factors of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Hepatocellular carcinoma arising in non-alcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Hepatocellular carcinoma with nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Hepatocellular carcinoma and nonalcoholic steatohepatitis developing during long-term administration of valproic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Two cases of non-alcoholic steatohepatitis with development of hepatocellular carcinoma without cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Hepatocellular carcinoma with silent and cirrhotic non-alcoholic steatohepatitis, accompanying ectopic liver tissue attached to gallbladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Primary liver cancers with nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Hepatocellular carcinoma arising from nonalcoholic steatohepatitis: report of two cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Nonalcoholic steatohepatitis-associated hepatocellular carcinoma: our case series and literature review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Etiology of non-B non-C hepatocellular carcinoma in the eastern district of Tokyo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Characteristics of patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Non-alcoholic fatty liver disease progresses to hepatocellular carcinoma in the absence of apparent cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Nonalcoholic steatohepatitis: cirrhosis, hepatocellular carcinoma, and burnt-out NASH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Obesity and diabetes as a risk factor for hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Hepatocellular carcinomas in patients with metabolic syndrome often develop without significant liver fibrosis: a pathological analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Report of the 18th follow-up survey of primary liver cancer in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Survival, liver failure, and hepatocellular carcinoma in obesity-related cryptogenic cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

Factors That Affect Risk for Hepatocellular Carcinoma and Effects of Surveillance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00872.X

10.1111/J.1872-034X.2011.00872.X

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference

PubMed ID

21917086