(Q37932294)

25 August 2017

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title

Stable isotopes in clinical pharmacokinetic investigations. Advantages and disadvantages (English)

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25 August 2017

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Browne TR

1

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25 August 2017

publication date

1 June 1990

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Clinical Pharmacokinetics

25 August 2017

published in

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25 August 2017

volume

18

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25 August 2017

issue

6

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25 August 2017

page(s)

423-433

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Studies with stable isotopes I: Changes in phenytoin pharmacokinetics and biotransformation during monotherapy

25 August 2017

cites work

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12 December 2020

The application of stable isotopes to studies of drug bioavailability and bioequivalence

1 reference

12 December 2020

Pharmacokinetic equivalence of stable-isotope-labeled and unlabeled drugs. Phenobarbital in man

1 reference

12 December 2020

New pharmacokinetic methods. III. Two simple test for "deep pool effect".

1 reference

12 December 2020

Bioavailability and kinetics of maprotiline

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12 December 2020

Applications to analytic chemistry: an evaluation of stable isotopes in mass spectral drug assays

1 reference

12 December 2020

Staggered stable isotope administration technique for study of drug distribution.

1 reference

12 December 2020

Fundamentals of present-day mass spectrometry

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12 December 2020

Superiority of stable isotope techniques in the assessment of the bioavailability of drugs undergoing extensive first pass elimination. Studies of the relative bioavailability of verapamil tablets

1 reference

12 December 2020

Estimation of the elimination half-life of a drug at any serum concentration when the Km and Vmax of the drug are known: calculations and validation with phenytoin

1 reference

12 December 2020

Drug biotransformation: mechanistic studies with stable isotopes

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12 December 2020

Carbamazepine increases phenytoin serum concentration and reduces phenytoin clearance

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12 December 2020

Stereoselective increase in propranolol bioavailability during chronic dosing in the dog

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12 December 2020

Integrated equation to evaluate accumulation profiles of drugs eliminated by Michaelis-Menten kinetics

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12 December 2020

Embryotoxicity of stable isotopes and use of stable isotopes in studies of teratogenetic mechanisms

1 reference

12 December 2020

Phenobarbital does not alter phenytoin steady-state serum concentration or pharmacokinetics

1 reference

12 December 2020

Determination of the in vivo Km and Vmax of a drug with tracer studies.

1 reference

12 December 2020

Studies with stable isotopes III: Pharmacokinetics of tracer doses of drug

1 reference

12 December 2020

Resolution of valproic acid from deuterated analogues and their quantitation in plasma using capillary gas chromatography

1 reference

12 December 2020

Use of stable isotopes in the elucidation of drug biotransformation processes

1 reference

12 December 2020

Single-dose pharmacokinetics of terodiline, including a stable isotope technique for improvement of statistical evaluations

1 reference

12 December 2020

The use of stable isotopes in metabolic investigation

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12 December 2020

Stable isotopes: origins and safety

1 reference

12 December 2020

Bioavailability of imipramine tablets relative to a stable isotope-labeled internal standard: Increasing the power of bioavailability tests

1 reference

12 December 2020

Bioavailability of ACC-9653 (phenytoin prodrug)

1 reference

12 December 2020

Mass spectrometry: preparation of biologic specimens

1 reference

12 December 2020

New pharmacokinetic methods. II: Determination of the presence or absence of product inhibition in drugs with nonlinear pharmacokinetics.

1 reference

12 December 2020

The effect of crystal size on the bioavailability of benoxaprofen: Studies utilizing deuterium labeled drug

1 reference

12 December 2020

Stereoselective interaction of phenylbutazone with [12C/13C]warfarin pseudoracemates in man

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12 December 2020

Kinetic equivalence of stable-isotope-labeled and unlabeled phenytoin

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12 December 2020

Isotope effects: definitions and consequences for pharmacologic studies

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12 December 2020

Pharmacokinetics: time-dependent changes--autoinduction of carbamazepine epoxidation

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12 December 2020

Studies with stable isotopes II: Phenobarbital pharmacokinetics during monotherapy

1 reference

12 December 2020

Biotransformation and excretion: metabolite identification: other mass spectrometric methods

1 reference

12 December 2020

10.2165/00003088-199018060-00001

Identifiers

DOI

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Dimensions Publication ID

25 August 2017

1045523590

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