(Q37939333)

25 August 2017

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title

Sex steroids and the control of the Kiss1 system: developmental roles and major regulatory actions (English)

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25 August 2017

D García-Galiano

1

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25 August 2017

L Pinilla

series ordinal

2

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25 August 2017

M Tena-Sempere

series ordinal

3

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25 August 2017

publication date

1 January 2012

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Journal of Neuroendocrinology

25 August 2017

published in

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25 August 2017

volume

24

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25 August 2017

issue

1

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25 August 2017

page(s)

22-33

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Sexual differentiation of the vertebrate nervous system.

25 August 2017

cites work

1 reference

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Postnatal development of an estradiol-kisspeptin positive feedback mechanism implicated in puberty onset

21 January 2018

1 reference

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21 January 2018

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Minireview: the neuroendocrine regulation of puberty: is the time ripe for a systems biology approach?

21 January 2018

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New frontiers in kisspeptin/GPR54 physiology as fundamental gatekeepers of reproductive function

21 January 2018

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Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54

21 January 2018

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The GPR54 gene as a regulator of puberty

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Kisspeptin signaling in the brain

21 January 2018

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The role of kisspeptin signaling in reproduction.

21 January 2018

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Roles of kisspeptins in the control of hypothalamic-gonadotropic function: focus on sexual differentiation and puberty onset.

21 January 2018

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Differential regulation of KiSS-1 mRNA expression by sex steroids in the brain of the male mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Regulation of Kiss1 gene expression in the brain of the female mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B.

21 January 2018

1 reference

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Structural interactions between kisspeptin and GnRH neurons in the mediobasal hypothalamus of the male rhesus monkey (Macaca mulatta) as revealed by double immunofluorescence and confocal microscopy

21 January 2018

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The kisspeptin system of the human hypothalamus: sexual dimorphism and relationship with gonadotropin-releasing hormone and neurokinin B neurons.

21 January 2018

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The neuroanatomy of the kisspeptin system in the mammalian brain

21 January 2018

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Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone neurons.

21 January 2018

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Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent: the case for the rostral periventricular area of the third ventricle (RP3V).

21 January 2018

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Kisspeptin neurons in the ovine arcuate nucleus and preoptic area are involved in the preovulatory luteinizing hormone surge.

21 January 2018

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Distribution of kisspeptin neurones in the adult female mouse brain.

21 January 2018

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Sexual differentiation of Kiss1 gene expression in the brain of the rat.

21 January 2018

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A role for kisspeptins in the regulation of gonadotropin secretion in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Regulation of Kiss1 expression by sex steroids in the amygdala of the rat and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Kisspeptin/GPR54 system as potential target for endocrine disruption of reproductive development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Significance of neonatal testicular sex steroids to defeminize anteroventral periventricular kisspeptin neurons and the GnRH/LH surge system in male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Reproductive Hormone-Dependent and -Independent Contributions to Developmental Changes in Kisspeptin in GnRH-Deficient Hypogonadal Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Effects of aromatase mutation (ArKO) on the sexual differentiation of kisspeptin neuronal numbers and their activation by same versus opposite sex urinary pheromones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Developmental Changes in the Expression of Kisspeptin mRNA in Rat Hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

The kisspeptin/neurokinin B/dynorphin (KNDy) cell population of the arcuate nucleus: sex differences and effects of prenatal testosterone in sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

BAX-dependent and BAX-independent regulation of Kiss1 neuron development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

The KiSS-1/GPR54 system: putative target for endocrine disruption of reproduction at hypothalamic-pituitary unit?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Increased hypothalamic GPR54 signaling: a potential mechanism for initiation of puberty in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Downregulation of metastasis suppressor genes in malignant pheochromocytoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Ontogeny and mechanisms of action for the stimulatory effect of kisspeptin on gonadotropin-releasing hormone system of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Desensitization of gonadotropin responses to kisspeptin in the female rat: analyses of LH and FSH secretion at different developmental and metabolic states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Critical roles of kisspeptins in female puberty and preovulatory gonadotropin surges as revealed by a novel antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Female reproductive maturation in the absence of kisspeptin/GPR54 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Gonadotropin-releasing hormone neuron requirements for puberty, ovulation, and fertility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Early metabolic programming of puberty onset: impact of changes in postnatal feeding and rearing conditions on the timing of puberty and development of the hypothalamic kisspeptin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Timing and completion of puberty in female mice depend on estrogen receptor alpha-signaling in kisspeptin neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

The role of kisspeptin-GPR54 signaling in the tonic regulation and surge release of gonadotropin-releasing hormone/luteinizing hormone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Kiss1 neurons in the forebrain as central processors for generating the preovulatory luteinizing hormone surge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Molecular characterization and estrogen regulation of hypothalamic KISS1 gene in the pig.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Identification of KiSS-1 product kisspeptin and steroid-sensitive sexually dimorphic kisspeptin neurons in medaka (oryzias latipes).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Regulation of Kiss1 and dynorphin gene expression in the murine brain by classical and nonclassical estrogen receptor pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Nonclassical estrogen receptor alpha signaling mediates negative feedback in the female mouse reproductive axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Estrogen regulates KiSS1 gene expression through estrogen receptor alpha and SP protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

KISS1 is down-regulated by 17beta-estradiol in MDA-MB-231 cells through a nonclassical mechanism and loss of ribonucleic acid polymerase II binding at the proximal promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Kisspeptin increases gamma-aminobutyric acidergic and glutamatergic transmission directly to gonadotropin-releasing hormone neurons in an estradiol-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Opposite roles of estrogen receptor (ER)-alpha and ERbeta in the modulation of luteinizing hormone responses to kisspeptin in the female rat: implications for the generation of the preovulatory surge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Follicle-stimulating hormone responses to kisspeptin in the female rat at the preovulatory period: modulation by estrogen and progesterone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Hypothalamic expression of KiSS-1 system and gonadotropin-releasing effects of kisspeptin in different reproductive states of the female Rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Kisspeptin-54 stimulates gonadotropin release most potently during the preovulatory phase of the menstrual cycle in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Neurokinin B acts via the neurokinin-3 receptor in the retrochiasmatic area to stimulate luteinizing hormone secretion in sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

TAC3 and TACR3 defects cause hypothalamic congenital hypogonadotropic hypogonadism in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Neurokinin B and the hypothalamic regulation of reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

The excitatory peptide kisspeptin restores the luteinizing hormone surge and modulates amino acid neurotransmission in the medial preoptic area of middle-aged rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Menopause and the human hypothalamus: evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Kisspeptin Activation of Gonadotropin Releasing Hormone Neurons and Regulation of KiSS-1 mRNA in the Male Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

Kisspeptin Is Essential for the Full Preovulatory LH Surge and Stimulates GnRH Release from the Isolated Ovine Median Eminence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02230.X

10.1111/J.1365-2826.2011.02230.X

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference