(Q37940646)

25 August 2017

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title

Lambda repressor: a model system for understanding protein-DNA interactions and protein stability (English)

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25 August 2017

Sauer RT

1

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25 August 2017

Jordan SR

series ordinal

2

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25 August 2017

Pabo CO

series ordinal

3

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25 August 2017

publication date

1 January 1990

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Advances in Protein Chemistry

25 August 2017

published in

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25 August 2017

volume

40

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25 August 2017

page(s)

1-61

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Quantitative model for gene regulation by lambda phage repressor

25 August 2017

cites work

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7 January 2021

Recognition of a DNA operator by the repressor of phage 434: a view at high resolution

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7 January 2021

Temperature-sensitive mutations of bacteriophage T4 lysozyme occur at sites with low mobility and low solvent accessibility in the folded protein

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7 January 2021

Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme

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7 January 2021

Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli

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7 January 2021

Cocrystals of the DNA-binding domain of phage 434 repressor and a synthetic phage 434 operator

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7 January 2021

Structure of the repressor-operator complex of bacteriophage 434.

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7 January 2021

Structure of the cro repressor from bacteriophage lambda and its interaction with DNA.

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7 January 2021

Maximizing gene expression on a plasmid using recombination in vitro

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7 January 2021

Construction of plasmids carrying the cI gene of bacteriophage lambda

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7 January 2021

Missing contact probing of DNA-protein interactions

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7 January 2021

The yeast regulatory gene PHO2 encodes a homeo box

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7 January 2021

Sequence-specific recognition of deoxyribonucleic acid. Chemical synthesis and nuclear magnetic resonance assignment of the imino protons of lambda OR3 operator deoxyribonucleic acid

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7 January 2021

Preferential cleavage of phage λ repressor monomers by recA protease

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https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

E. coli recA protein-directed cleavage of phage λ repressor requires polynucleotide

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7 January 2021

Systematic method for the detection of potential lambda Cro-like DNA-binding regions in proteins.

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https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

NH2-terminal arm of phage lambda repressor contributes energy and specificity to repressor binding and determines the effects of operator mutations

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https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Mutational analysis of the operators of bacteriophage lambda

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https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Mutations in bacteriophage lambda repressor that prevent RecA-mediated cleavage

1 reference

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7 January 2021

Lambda repressor inactivation: properties of purified ind- proteins in the autodigestion and RecA-mediated cleavage reactions

1 reference

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7 January 2021

Lambda repressor mutants that are better substrates for RecA-mediated cleavage.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

DNA loops induced by cooperative binding of lambda repressor

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7 January 2021

Mutant lambda phage repressor with a specific defect in its positive control function

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7 January 2021

The effect of a lambda repressor mutation on the activation of transcription initiation from the lambda PRM promoter

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https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Phage lambda repressor revertants. Amino acid substitutions that restore activity to mutant proteins

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https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Mutations in lambda repressor's amino-terminal domain: implications for protein stability and DNA binding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Effect of single amino acid replacements on the thermal stability of the NH2-terminal domain of phage lambda repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Increasing and decreasing protein stability: effects of revertant substitutions on the thermal denaturation of phage lambda repressor.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Stabilization of lambda repressor against thermal denaturation by site-directed Gly----Ala changes in alpha-helix 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Homologous interactions of lambda repressor and lambda Cro with the lambda operator

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Cooperative binding of lambda repressors to sites separated by integral turns of the DNA helix

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Repressor structure and the mechanism of positive control

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

How lambda repressor and lambda Cro distinguish between OR1 and OR3.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

The alpha-helix dipole and the properties of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Nucleotide sequence of the lexA gene of E. coli

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Completed DNA sequences and organization of repressor-binding sites in the operators of phage lambda

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Sites of contact between lambda operators and lambda repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

A new way of enhancing the thermostability of proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

On the attribution and additivity of binding energies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Mechanism of action of the cro protein of bacteriophage lambda

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Interactions between DNA-bound repressors govern regulation by the λ phage repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

lambda Repressor and cro--components of an efficient molecular switch

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Structure of the lambda complex at 2.5 A resolution: details of the repressor-operator interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Systematic variation in DNA length yields highly ordered repressor-operator cocrystals.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

A protein structure from nuclear magnetic resonance data. lac repressor headpiece

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins

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https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

The interpretation of protein structures: Estimation of static accessibility

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Structure of the Operator-binding Domain of Bacteriophage Repressor: Implications for DNA Recognition and Gene Regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Autodigestion of lexA and phage lambda repressors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Structure of the λ Operators

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Multiple Repressor Binding at the Operators in Bacteriophage λ

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Cumulative effect of intragenic amino-acid replacements on the thermostability of a protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Structure of the DNA-binding region of lac repressor inferred from its homology with cro repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Enhanced protein thermostability from site-directed mutations that decrease the entropy of unfolding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Promoters are in the operators in phage lambda.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Gene regulation at the right operator (OR) bacteriophage lambda. I. OR3 and autogenous negative control by repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Mechanism and control of transcription initiation in prokaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Structure of catabolite gene activator protein at 2.9 A resolution suggests binding to left-handed B-DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Gene regulation at the right operator (OR) of bacteriophage lambda. III. lambda repressor directly activates gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Lambda repressor turns off transcription of its own gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Gene regulation at the right operator (OR) of bacteriophage lambda. II. OR1, OR2, and OR3: their roles in mediating the effects of repressor and cro.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Lambda repressor mutations that increase the affinity and specificity of operator binding.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Interaction of mutant lambda repressors with operator and non-operator DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Mutations Defining the Operator-binding Sites of Bacteriophage Repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

The molecular basis of DNA-protein recognition inferred from the structure of cro repressor.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Comparison of the structures of cro and lambda repressor proteins from bacteriophage lambda

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Deletion mapping of trans dominant mutations in the λ repressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Mutations in the right operator of bacteriophage lambda: evidence for operator-promoter interpenetration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Crystal structure of trp repressor/operator complex at atomic resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

The operator-binding domain of lambda repressor: structure and DNA recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Protein-DNA recognition

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https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Computer-aided model-building strategies for protein design

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

The lambda repressor contains two domains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

The N-terminal arms of lambda repressor wrap around the operator DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Entropic Contributions to Rate Accelerations in Enzymic and Intramolecular Reactions and the Chelate Effect

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Amino acid substitutions that increase the thermal stability of the lambda Cro protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Bacteriophage lambda cro mutations: effects on activity and intracellular degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Protein engineering of subtilisin BPN': enhanced stabilization through the introduction of two cysteines to form a disulfide bond

1 reference

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7 January 2021

Disulfide bond engineered into T4 lysozyme: stabilization of the protein toward thermal inactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Kinetics of RecA protein-directed inactivation of repressors of phage lambda and phage P22.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

ISOLATION OF THE lambda PHAGE REPRESSOR

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Specific Binding of the λ Phage Repressor to λ DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Ion effects on ligand-nucleic acid interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Combinatorial cassette mutagenesis as a probe of the informational content of protein sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Amino acid preferences for specific locations at the ends of alpha helices

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Proteolytic cleavage of bacteriophage lambda repressor in induction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Escherichia coli recA gene product inactivates phage lambda repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

DNA sequence of the bacteriophage gama cI gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Primary structure of the λ repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Regulatory functions of the lambda repressor reside in the amino-terminal domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Homology among DNA-binding proteins suggests use of a conserved super-secondary structure

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

An engineered intersubunit disulfide enhances the stability and DNA binding of the N-terminal domain of lambda repressor.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Guanidine hydrochloride denaturation studies of mutant forms of staphylococcal nuclease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Lysine-156 and serine-119 are required for LexA repressor cleavage: a possible mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Intramolecular cleavage of LexA and phage lambda repressors: dependence of kinetics on repressor concentration, pH, temperature, and solvent

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Combining thermostable mutations increases the stability of lambda repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Mechanism of action of Salmonella phage P22 antirepressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Hydroxyl radical "footprinting": high-resolution information about DNA-protein contacts and application to lambda repressor and Cro protein

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https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Imino proton assignments in the proton nuclear magnetic resonance spectrum of the .lambda. phage OR3 deoxyribonucleic acid fragment

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Solution NMR studies of intact lambda repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Two-dimensional 1H NMR study of the lambda operator site OL1: a sequential assignment strategy and its application

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

1H-NMR study of the λ operator siteOL1: assignment of the imino and adenine H2 resonances

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Amino-terminal arm of the lambda repressor: a 1H NMR study

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Dynamic filtering by two-dimensional 1H NMR with application to phage lambda repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Quaternary structure and function in phage lambda repressor: 1H-NMR studies of genetically altered proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

1H NMR aromatic spectrum of the operator binding domain of the lambda repressor: resonance assignment with application to structure and dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Dimerization of the operator binding domain of phage lambda repressor.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Changing the binding specificity of a repressor by redesigning an alpha-helix

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

Structure of a phage 434 Cro/DNA complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2808%2960286-7

7 January 2021

10.1016/S0065-3233(08)60286-7

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