(Q37943784)

25 August 2017

Canalicular ABC transporters and liver disease (English)

1 reference

25 August 2017

5

1 reference

25 August 2017

Michael Nicolaou

1

1 reference

25 August 2017

Edward J Andress

2

1 reference

25 August 2017

Joseph K Zolnerciks

3

1 reference

25 August 2017

Peter H Dixon

4

1 reference

25 August 2017

Kenneth J Linton

6

1 reference

25 August 2017

1 January 2012

1 reference

25 August 2017

1 reference

25 August 2017

226

1 reference

25 August 2017

2

1 reference

25 August 2017

300-315

1 reference

Bile acids: chemistry, pathochemistry, biology, pathobiology, and therapeutics

25 August 2017

1 reference

The enzymes, regulation, and genetics of bile acid synthesis

21 January 2018

1 reference

The human bile salt export pump: characterization of substrate specificity and identification of inhibitors

21 January 2018

1 reference

21 January 2018

Bile acid biosynthesis

1 reference

The enterohepatic circulation of bile acids in mammals: form and functions

21 January 2018

1 reference

Enterohepatic bile salt transporters in normal physiology and liver disease

21 January 2018

1 reference

21 January 2018

Bile salt transporters

1 reference

Bile salt transporters: molecular characterization, function, and regulation

21 January 2018

1 reference

The sodium bile salt cotransport family SLC10

21 January 2018

1 reference

Radiation-inactivation analysis of the Na+/bile acid co-transport system from rabbit ileum

21 January 2018

1 reference

Molecular cloning, tissue distribution, and expression of a 14-kDa bile acid-binding protein from rat ileal cytosol

21 January 2018

1 reference

The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter

21 January 2018

1 reference

Functional Complementation between a Novel Mammalian Polygenic Transport Complex and an Evolutionarily Ancient Organic Solute Transporter, OSTα-OSTβ

21 January 2018

1 reference

Organic solute transporter, OSTalpha-OSTbeta: its role in bile acid transport and cholestasis

21 January 2018

1 reference

21 January 2018

Bile acid transporters

1 reference

Hepatic transport of bile salts

21 January 2018

1 reference

Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter

21 January 2018

1 reference

Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake

21 January 2018

1 reference

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

21 January 2018

1 reference

Bile acid transporters: structure, function, regulation and pathophysiological implications

21 January 2018

1 reference

The superfamily of organic anion transporting polypeptides

21 January 2018

1 reference

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver

21 January 2018

1 reference

Identification of glutathione as a driving force and leukotriene C4 as a substrate for oatp1, the hepatic sinusoidal organic solute transporter.

21 January 2018

1 reference

Organic anion transporting polypeptide mediates organic anion/HCO3- exchange

21 January 2018

1 reference

Further characterization of the electrogenicity and pH sensitivity of the human organic anion-transporting polypeptides OATP1B1 and OATP1B3.

21 January 2018

1 reference

Intracellular transport of bile acids

21 January 2018

1 reference

21 January 2018

1 reference

Trafficking and transporter disorders in pediatric cholestasis

21 January 2018

1 reference

Rat liver canalicular membrane vesicles contain an ATP-dependent bile acid transport system

21 January 2018

1 reference

ATP-dependent bile-salt transport in canalicular rat liver plasma-membrane vesicles

21 January 2018

1 reference

The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver

21 January 2018

1 reference

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

21 January 2018

1 reference

Functional expression of the canalicular bile salt export pump of human liver

21 January 2018

1 reference

Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis

21 January 2018

1 reference

Bile acid transport in sister of P-glycoprotein (ABCB11) knockout mice

21 January 2018

1 reference

Expression and localization of hepatobiliary transport proteins in progressive familial intrahepatic cholestasis

21 January 2018

1 reference

Bile Salt Export Pump Gene Mutations in Two Japanese Patients With Progressive Familial Intrahepatic Cholestasis

21 January 2018

1 reference

Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis

21 January 2018

1 reference

Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

21 January 2018

1 reference

Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing

21 January 2018

1 reference

Progressive familial intrahepatic cholestasis

21 January 2018

1 reference

Progressive familial intrahepatic cholestasis (PFIC) type 1, 2, and 3: a review of the liver pathology findings

21 January 2018

1 reference

A patient with novel ABCB11 gene mutations with phenotypic transition between BRIC2 and PFIC2.

21 January 2018

1 reference

Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis

21 January 2018

1 reference

Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy

21 January 2018

1 reference

Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy

21 January 2018

1 reference

Genetic variability, haplotype structures, and ethnic diversity of hepatic transporters MDR3 (ABCB4) and bile salt export pump (ABCB11).

21 January 2018

1 reference

Enterohepatic transport of bile salts and genetics of cholestasis

21 January 2018

1 reference

Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump

21 January 2018

1 reference

Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy

21 January 2018

1 reference

Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver

21 January 2018

1 reference

Hepatocellular carcinoma in ten children under five years of age with bile salt export pump deficiency

21 January 2018

1 reference

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

21 January 2018

1 reference

MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

21 January 2018

1 reference

Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice.

21 January 2018

1 reference

The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood

21 January 2018

1 reference

ABCB4 gene sequence variation in women with intrahepatic cholestasis of pregnancy.

21 January 2018

1 reference

Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein).

21 January 2018

1 reference

MDR3 gene defect in adults with symptomatic intrahepatic and gallbladder cholesterol cholelithiasis

21 January 2018

1 reference

Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy

21 January 2018

1 reference

Multidrug resistance 3 gene mutation 1712delT and estrogen receptor alpha gene polymorphisms in Finnish women with obstetric cholestasis

21 January 2018

1 reference

A second heterozygous MDR3 nonsense mutation associated with intrahepatic cholestasis of pregnancy

21 January 2018

1 reference

Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking

21 January 2018

1 reference

A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature.

21 January 2018

1 reference

Complementary functions of the flippase ATP8B1 and the floppase ABCB4 in maintaining canalicular membrane integrity.

21 January 2018

1 reference

A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis

21 January 2018

1 reference

ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity

21 January 2018

1 reference

Familial intrahepatic cholestasis 1: studies of localization and function

21 January 2018

1 reference

ATP8B1 mutations in British cases with intrahepatic cholestasis of pregnancy.

21 January 2018

1 reference

Sequence variation in the ATP8B1 gene and intrahepatic cholestasis of pregnancy

21 January 2018

1 reference

Characterization of mutations in ATP8B1 associated with hereditary cholestasis

21 January 2018

1 reference

ATP8B1 is essential for maintaining normal hearing

21 January 2018

1 reference

Recurrent familial intrahepatic cholestasis in the Faeroe Islands. Phenotypic heterogeneity but genetic homogeneity

21 January 2018

1 reference

EASL Clinical Practice Guidelines: management of cholestatic liver diseases.

21 January 2018

1 reference

Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'.

21 January 2018

1 reference

Ursodeoxycholic acid treatment in children with Byler disease

21 January 2018

1 reference

Liver disease associated with canalicular transport defects: current and future therapies

21 January 2018

1 reference

Use of rifampin for severe pruritus in children with chronic cholestasis

21 January 2018

1 reference

Effect of cholestyramine on bile acid metabolism in normal man

21 January 2018

1 reference

Selective surgical management of progressive familial intrahepatic cholestasis (Byler's disease).

21 January 2018

1 reference

Nasobiliary drainage induces long-lasting remission in benign recurrent intrahepatic cholestasis

21 January 2018

1 reference

Allograft steatohepatitis in progressive familial intrahepatic cholestasis type 1 after living donor liver transplantation.

21 January 2018

1 reference

De novo bile salt transporter antibodies as a possible cause of recurrent graft failure after liver transplantation: a novel mechanism of cholestasis

21 January 2018

1 reference

Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes

21 January 2018

1 reference

Membrane lipids: where they are and how they behave

21 January 2018

1 reference

A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells

21 January 2018

1 reference

Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy

21 January 2018

1 reference

"Don't know much bile-ology"

21 January 2018

1 reference

Nuclear orphan receptors control cholesterol catabolism.

21 January 2018

1 reference

Identification of a nuclear receptor for bile acids

21 January 2018

1 reference

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

1 reference

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

1 reference

Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

21 January 2018

1 reference

Farnesoid X Receptor Activates Transcription of the Phospholipid Pump MDR3

21 January 2018

1 reference

Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface

21 January 2018

1 reference

NPC1L1 and cholesterol transport

21 January 2018

1 reference

Comparison of intestinal absorption of cholesterol with different plant sterols in man.

21 January 2018

1 reference

Metabolism of beta-sitosterol in man.

21 January 2018

1 reference

Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21

21 January 2018

1 reference

Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption

21 January 2018

1 reference

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

21 January 2018

1 reference

Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis

21 January 2018

1 reference

Rapid quantification of free and esterified phytosterols in human serum using APPI-LC-MS/MS.

21 January 2018

1 reference

Specificity of the commonly used enzymatic assay for plasma cholesterol determination

21 January 2018

1 reference

Sitosterolemia--a rare disease. Are elevated plant sterols an additional risk factor?

21 January 2018

1 reference

β-Sitosterolemia and Xanthomatosis

21 January 2018

1 reference

Stomatocytic haemolysis and macrothrombocytopenia (Mediterranean stomatocytosis/macrothrombocytopenia) is the haematological presentation of phytosterolaemia

21 January 2018

1 reference

Intestinal cholesterol absorption inhibitor ezetimibe added to cholestyramine for sitosterolemia and xanthomatosis.

21 January 2018

1 reference

No association between plasma levels of plant sterols and atherosclerosis in mice and men.

21 January 2018

1 reference

Sitosterol-containing lipoproteins trigger free sterol-induced caspase-independent death in ACAT-competent macrophages

21 January 2018

1 reference

Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes

21 January 2018

1 reference

Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

21 January 2018

1 reference

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

21 January 2018

1 reference

Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition

21 January 2018

1 reference

Chronic idiopathic jaundice with unidentified pigment in liver cells; a new clinicopathologic entity with a report of 12 cases

21 January 2018

1 reference

Characterization of mice lacking the multidrug resistance protein MRP2 (ABCC2).

21 January 2018

1 reference

Effect of ABCC2 (MRP2) transport function on erythromycin metabolism

21 January 2018

1 reference

Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo

21 January 2018

1 reference

Effects of cytochrome P450 3A (CYP3A) and the drug transporters P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir

21 January 2018

1 reference

Individual and combined roles of CYP3A, P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) in the pharmacokinetics of docetaxel

21 January 2018

1 reference

P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 determine the pharmacokinetics of etoposide

21 January 2018

1 reference

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

21 January 2018

1 reference

A multidrug resistance transporter from human MCF-7 breast cancer cells

21 January 2018

1 reference

Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

21 January 2018

1 reference

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues.

21 January 2018

1 reference

The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane.

21 January 2018

1 reference

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

21 January 2018

1 reference

Localisation of breast cancer resistance protein in microvessel endothelium of human brain

21 January 2018

1 reference

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

21 January 2018

1 reference

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

21 January 2018

1 reference

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

The physiological function of drug-transporting P-glycoproteins

21 January 2018

1 reference

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

21 January 2018

1 reference

Physiological and pharmacological roles of ABCG2 (BCRP): recent findings in Abcg2 knockout mice

21 January 2018

1 reference

Involvement of breast cancer resistance protein (ABCG2) in the biliary excretion mechanism of fluoroquinolones.

21 January 2018

1 reference

The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues

21 January 2018

1 reference

A "silent" polymorphism in the MDR1 gene changes substrate specificity

21 January 2018

1 reference

FIC1 and BSEP defects in Taiwanese patients with chronic intrahepatic cholestasis with low γ-glutamyltranspeptidase levels

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/PATH.3019

1 reference

25 August 2017

1 reference