(Q37949574)

25 August 2017

title

Working without kinase activity: phosphotransfer-independent functions of extracellular signal-regulated kinases (English)

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25 August 2017

Javier Rodríguez

1

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25 August 2017

Piero Crespo

series ordinal

2

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25 August 2017

publication date

25 October 2011

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25 August 2017

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25 August 2017

volume

4

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25 August 2017

issue

196

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25 August 2017

page(s)

re3

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Differential regulation and properties of MAPKs

25 August 2017

cites work

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PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

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Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

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ERK nuclear translocation is dimerization-independent but controlled by the rate of phosphorylation

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The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

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New insights into the catalytic activation of the MAPK phosphatase PAC-1 induced by its substrate MAPK ERK2 binding

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Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and their ability to activate the phosphatase catalytically

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Characterization of a murine gene encoding a developmentally regulated cytoplasmic dual-specificity mitogen-activated protein kinase phosphatase

21 January 2018

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Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5

21 January 2018

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Spatio-temporal regulation of mitogen-activated protein kinase (MAPK) signalling by protein phosphatases.

21 January 2018

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Poly(ADP-ribose): novel functions for an old molecule

21 January 2018

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DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation

21 January 2018

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Type II topoisomerases--inhibitors, repair mechanisms and mutations

21 January 2018

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DNA topoisomerase II enzymes as molecular targets for cancer chemotherapy

21 January 2018

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Extracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation

21 January 2018

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Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation

21 January 2018

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Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK

21 January 2018

1 reference

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Chromatin-bound mitogen-activated protein kinases transmit dynamic signals in transcription complexes in beta-cells

21 January 2018

1 reference

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Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling

21 January 2018

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CCAAT/enhancer-binding protein-beta regulates interferon-induced transcription through a novel element

21 January 2018

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ERK implication in cell cycle regulation

21 January 2018

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Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

21 January 2018

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Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase

21 January 2018

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Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells

21 January 2018

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The retinoblastoma protein and cell cycle control

21 January 2018

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Role of A-type lamins in signaling, transcription, and chromatin organization.

21 January 2018

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Lamins: 'structure goes cycling'.

21 January 2018

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A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C.

21 January 2018

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Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope

21 January 2018

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ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma-lamin A complexes.

21 January 2018

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Noncatalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling

21 January 2018

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IQGAP1 in cellular signaling: bridging the GAP.

21 January 2018

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Beta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transduction

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Dystroglycan versatility in cell adhesion: a tale of multiple motifs

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Paxillin and focal adhesion signalling

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Identification and characterization of a general nuclear translocation signal in signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Stimulus-induced uncoupling of extracellular signal-regulated kinase phosphorylation from nuclear localization is dependent on docking domain interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Evidence for existence of a nuclear pore complex-mediated, cytosol-independent pathway of nuclear translocation of ERK MAP kinase in permeabilized cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

The nuclear localization of ERK2 occurs by mechanisms both independent of and dependent on energy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Involvement of the activation loop of ERK in the detachment from cytosolic anchoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

10.1126/SCISIGNAL.2002324

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference