(Q37953810)

25 August 2017

Genetics of susceptibility and treatment response in psoriatic arthritis (English)

1 reference

25 August 2017

Darren D O'Rielly

1

1 reference

PubMed ID

22064628

25 August 2017

Proton Rahman

series ordinal

2

1 reference

PubMed ID

22064628

25 August 2017

language of work or name

English

0 references

publication date

8 November 2011

1 reference

Nature Reviews Rheumatology

25 August 2017

1 reference

25 August 2017

7

1 reference

25 August 2017

12

1 reference

25 August 2017

718-732

1 reference

https://scigraph.springernature.com/pub.10.1038/nrrheum.2011.169

25 August 2017

0 references

cites work

Genetic epidemiology of psoriasis and psoriatic arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

The prevalence of psoriatic arthritis in people with psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Psoriatic arthritis: epidemiology, clinical features, course, and outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Efficacy and safety of anti-TNF therapies in psoriatic arthritis: an observational study from the British Society for Rheumatology Biologics Register

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Efficacy and tolerability of anti-tumour necrosis factor therapy in psoriatic arthritis patients: results from the South Swedish Arthritis Treatment Group register

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Mechanisms of TNF-alpha- and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Familial occurrence of psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Familial aggregation of psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Natural history of psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Linkage analysis of human leukocyte antigen (HLA) markers in familial psoriasis: strong disequilibrium effects provide evidence for a major determinant in the HLA-B/-C region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Multiple Loci within the major histocompatibility complex confer risk of psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Histocompatibility typing in the seronegative spondyloarthropathies: a survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

The role of HLA antigens as indicators of disease progression in psoriatic arthritis. Multivariate relative risk model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

TNFalpha polymorphisms and risk of psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

A whole-genome association study of major determinants for host control of HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Genome-wide studies of psoriasis susceptibility loci: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

A susceptibility gene for psoriatic arthritis maps to chromosome 16q: evidence for imprinting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Genetics of psoriasis in Iceland: evidence for linkage of subphenotypes to distinct Loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Association analyses identify six new psoriasis susceptibility loci in the Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Genome-wide association analysis identifies three psoriasis susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Investigation of association of the IL12B and IL23R genes with psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Deletion of the late cornified envelope genes LCE3C and LCE3B is associated with psoriasis in a Chinese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Mutation analysis of the LCE3B/LCE3C genes in Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Meta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

A milieu of regulatory elements in the epidermal differentiation complex syntenic block: implications for atopic dermatitis and psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Human beta-defensin-2 functions as a chemotactic agent for tumour necrosis factor-alpha-treated human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Psoriasis is associated with increased beta-defensin genomic copy number

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Expression and regulation of antimicrobial peptides in articular joints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Upregulation of connexin 26 between keratinocytes of psoriatic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

21 January 2018

NF-κB in immunobiology.

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

ABINs: A20 binding inhibitors of NF-kappa B and apoptosis signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Role of NFKB2 on the early myeloid differentiation of CD34+ hematopoietic stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Resident and "inflammatory" dendritic cells in human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Tyrosine kinase 2 (TYK2) in cytokine signalling and host immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

IL-17 and Th17 cells in human inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Interleukin-12 p40 gene (IL12B) 3'-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Polymorphisms of the IL12B and IL23R genes are associated with psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Th17 cells in human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

ER aminopeptidases generate a unique pool of peptides for MHC class I molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Update on the genetics of spondyloarthritis--ankylosing spondylitis and psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Detecting shared pathogenesis from the shared genetics of immune-related diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Unifying candidate gene and GWAS Approaches in Asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Two independent alleles at 6q23 associated with risk of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Rheumatoid arthritis association at 6q23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

A genetic risk score combining ten psoriasis risk loci improves disease prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

HLA-Cw6 and HLA-DRB1*07 together are associated with less severe joint disease in psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Genetic variation in efflux transporters influences outcome to methotrexate therapy in patients with psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Folate pathway enzyme gene polymorphisms and the efficacy and toxicity of methotrexate in psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

TNF-alpha-308 G/A polymorphism and responsiveness to TNF-alpha blockade therapy in moderate to severe rheumatoid arthritis: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Immunopathology of psoriasis and psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

TNFalpha therapy in psoriatic arthritis and psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

TNF polymorphisms in psoriasis: Association of psoriatic arthritis with the promoter polymorphismTNF*-857 independent of thePSORS1 risk allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Polymorphisms in Folate, Pyrimidine, and Purine Metabolism Are Associated with Efficacy and Toxicity of Methotrexate in Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Classification criteria for psoriatic arthritis: development of new criteria from a large international study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Distinct vascular patterns of early synovitis in psoriatic, reactive, and rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

HLA-DRB1∗04 alleles in psoriatic arthritis: comparison with rheumatoid arthritis and healthy controls

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Investigating the role of the HLA-Cw*06 and HLA-DRB1 genes in susceptibility to psoriatic arthritis: comparison with psoriasis and undifferentiated inflammatory arthritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

The MICA-A9 triplet repeat polymorphism in the transmembrane region confers additional susceptibility to the development of psoriatic arthritis and is independent of the association of Cw*0602 in psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Cutting edge: heterozygote advantage in autoimmune disease: hierarchy of protection/susceptibility conferred by HLA and killer Ig-like receptor combinations in psoriatic arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Cutting edge: susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Genetic Variants of the IL-23R Pathway: Association with Psoriatic Arthritis and Psoriasis Vulgaris, but No Specific Risk Factor for Arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Replication of LCE3C–LCE3B CNV as a Risk Factor for Psoriasis and Analysis of Interaction with Other Genetic Risk Factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Act1-ivating IL-17 inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Association between IL13 polymorphisms and psoriatic arthritis is modified by smoking.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Cytokine gene polymorphisms in Chinese patients with psoriasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

A variant of theIL4I50V single‐nucleotide polymorphism is associated with erosive joint disease in psoriatic arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Liver biopsy in psoriasis. A controlled study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Tumour necrosis factor (TNF) gene polymorphism influences TNF-alpha production in lipopolysaccharide (LPS)-stimulated whole blood cell culture in healthy humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Tumour necrosis factor (TNF)alpha -308 G/G promoter polymorphism and TNFalpha levels correlate with a better response to adalimumab in patients with rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

TNF Inhibition Rapidly Down-Regulates Multiple Proinflammatory Pathways in Psoriasis Plaques

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Effects of etanercept are distinct from infliximab in modulating proinflammatory genes in activated human leukocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

IL13 gene polymorphism is a marker for psoriatic arthritis among psoriasis patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.169

Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease

31 March 2020

1 reference

12 December 2020

Genetics of psoriasis and psoriatic arthritis: update and future direction.

1 reference

12 December 2020

From skin to bone: translational perspectives on psoriatic disease

1 reference

12 December 2020

Risks and benefits of tumor necrosis factor-alpha inhibitors in the management of psoriatic arthritis: systematic review and metaanalysis of randomized controlled trials.

1 reference

12 December 2020

Angiopoietins, growth factors, and vascular morphology in early arthritis.

1 reference

12 December 2020

Clinical and immunogenetic subsets of psoriatic arthritis.

1 reference

12 December 2020

Pharmacogenetics of rheumatoid arthritis: Potential targets from susceptibility genes and present therapies

1 reference

12 December 2020

Human lymphocyte antigens characterizing psoriatic arthritis and its subtypes

1 reference

12 December 2020

HLA antigens in psoriatic arthritis

1 reference

12 December 2020

Increased intercellular communication through gap junctions may contribute to progression of osteoarthritis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2011.169

1 reference

25 August 2017

1 reference

PubMed ID

22064628