(Q37959017)

25 August 2017

title

TGF-β and its coreceptors in cancerogenesis: an overview (English)

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25 August 2017

author name string

Nataša Todorović-Raković

series ordinal

1

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25 August 2017

Jelena Milovanović

series ordinal

2

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25 August 2017

Dragica Nikolić-Vukosavljević

series ordinal

3

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25 August 2017

publication date

1 December 2011

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25 August 2017

published in

Biomarkers in Medicine

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25 August 2017

volume

5

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25 August 2017

issue

6

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25 August 2017

page(s)

855-863

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Peptide growth factors are multifunctional

25 August 2017

cites work

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Protein ectodomain shedding

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Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways

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1 reference

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

21 January 2018

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Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II

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Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

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Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction

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TGF-beta receptor function in the endothelium.

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Endoglin expression in metastatic breast cancer cells enhances their invasive phenotype

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Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma

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Both high intratumoral microvessel density determined using CD105 antibody and elevated plasma levels of CD105 in colorectal cancer patients correlate with poor prognosis

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Expression of endoglin (CD105) in cervical cancer

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Endoglin expression in breast tumor cells suppresses invasion and metastasis and correlates with improved clinical outcome.

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Endoglin suppresses human prostate cancer metastasis

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Endoglin (CD105) expression in ovarian serous carcinoma effusions is related to chemotherapy status

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TbetaR-II discriminates the high- and low-affinity TGF-beta isoforms via two hydrogen-bonded ion pairs

21 January 2018

1 reference

Functional roles for the cytoplasmic domain of the type III transforming growth factor beta receptor in regulating transforming growth factor beta signaling

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Extracellular domain of TGFbeta type III receptor inhibits angiogenesis and tumor growth in human cancer cells

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TbetaRIII suppresses non-small cell lung cancer invasiveness and tumorigenicity

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Expression of the type III TGF-beta receptor is negatively regulated by TGF-beta

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Knockdown of the transforming growth factor-beta type III receptor impairs motility and invasion of metastatic cancer cells

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites

21 January 2018

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Endoglin is expressed on human chondrocytes and forms a heteromeric complex with betaglycan in a ligand and type II TGFbeta receptor independent manner

21 January 2018

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Transforming growth factor-beta in breast cancer: too much, too late

21 January 2018

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Plasma levels of soluble CD105 correlate with metastasis in patients with breast cancer

21 January 2018

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New insights into TGF-beta-Smad signalling

21 January 2018

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Novel biochemical pathways of endoglin in vascular cell physiology.

21 January 2018

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Cirrhotic hepatocytes exhibit decreased TGFbeta growth inhibition associated with downregulated Smad protein expression

21 January 2018

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Endoglin differentially regulates TGF-β-induced Smad2/3 and Smad1/5 signalling and its expression correlates with extracellular matrix production and cellular differentiation state in human chondrocytes

21 January 2018

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Endoglin inhibits prostate cancer motility via activation of the ALK2-Smad1 pathway

21 January 2018

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Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.

21 January 2018

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

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The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras

21 January 2018

1 reference

Betaglycan induces TGF-beta signaling in a ligand-independent manner, through activation of the p38 pathway

21 January 2018

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Targeting cancer vasculature via endoglin/CD105: a novel antibody-based diagnostic and therapeutic strategy in solid tumours

21 January 2018

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The emerging role of TGF-beta superfamily coreceptors in cancer.

21 January 2018

1 reference

Silencing of transforming growth factor-beta1 in situ by RNA interference for breast cancer: implications for proliferation and migration in vitro and metastasis in vivo

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/BMM.11.59

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25 August 2017

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