(Q37959814)

25 August 2017

title

Bee venom in cancer therapy (English)

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25 August 2017

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Nada Oršolić

1

1 reference

25 August 2017

publication date

1 June 2012

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Cancer and Metastasis Reviews

25 August 2017

published in

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25 August 2017

volume

31

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25 August 2017

issue

1-2

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25 August 2017

page(s)

173-194

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https://scigraph.springernature.com/pub.10.1007/s10555-011-9339-3

25 August 2017

exact match

0 references

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Melittin: a membrane-active peptide with diverse functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Antiarthritic effect of bee venom: inhibition of inflammation mediator generation by suppression of NF-kappaB through interaction with the p50 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Effect of honey bee venom on proliferation of K1735M2 mouse melanoma cells in-vitro and growth of murine B16 melanomas in-vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Influence of honey bee products on transplantable murine tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Inhibition of mammary carcinoma cell proliferation in vitro and tumor growth in vivo by bee venom.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Cytotoxic properties of immunoconjugates containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Inhibition of COX-2 activity and proinflammatory cytokines (TNF-alpha and IL-1beta) production by water-soluble sub-fractionated parts from bee (Apis mellifera) venom

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Bee venom induces apoptosis and inhibits expression of cyclooxygenase-2 mRNA in human lung cancer cell line NCI-H1299.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Microarray analysis of gene expression in chondrosarcoma cells treated with bee venom

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Effect of polypeptides in bee venom on growth inhibition and apoptosis induction of the human hepatoma cell line SMMC-7721 in-vitro and Balb/c nude mice in-vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Effect of honey bee venom on microglial cells nitric oxide and tumor necrosis factor-alpha production stimulated by LPS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Bee venom induces apoptosis through caspase-3 activation in synovial fibroblasts of patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Photoprotective effects of green tea polyphenols

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Membrane disrupting lytic peptides for cancer treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Three-dimensional structure of membrane and surface proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

All-D amino acid-containing channel-forming antibiotic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Mechanism of membrane damage induced by the amphipathic peptides gramicidin S and melittin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

The actions of melittin on membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Sizing membrane pores in lipid vesicles by leakage of co-encapsulated markers: pore formation by melittin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Stimulation of luteinizing hormone release by melittin and phospholipase A2 in rat pituitary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Electron microscopic observation of the aggregation of membrane proteins in human erythrocyte by melittin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Effect of melittin on PD, resistance and short-circuit current in the frog gastric mucosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Involvement of protein kinase and G proteins in the signal transduction of benzophenanthridine alkaloid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Activation of insect cell adenylate cyclase by Bacillus thuringiensis delta-endotoxins and melittin. Toxicity is independent of cyclic AMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Activation of phosphoinositide-specific phospholipase C delta from rat liver by polyamines and basic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Thrombin and melittin activate phospholipase C in human HaCaT keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Phospholipase A2-mediated activation of phospholipase D in rat heart sarcolemma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Melittin activates endogenous phospholipase D during cytolysis of human monocytic leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Melittin, a metabostatic peptide inhibiting Gs activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

The expanding superfamily of phospholipase A(2) enzymes: classification and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

What can venom phospholipases A(2) tell us about the functional diversity of mammalian secreted phospholipases A(2)?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

21 January 2018

Phospholipase A2 enzymes

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Receptors for a growing family of secreted phospholipases A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2 in murine bone marrow-derived mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Lysophosphatidylcholine as a ligand for immunoregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Synthesis and biological activity of anticancer ether lipids that are specifically released by phospholipase A2 in tumor tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Synthesis and use of novel ether phospholipid enantiomers to probe the molecular basis of the antitumor Effects of alkyllysophospholipids: correlation of differential activation of c-Jun NH(2)-terminal protein kinase with antiproliferative effects i

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Expression of antimicrobial peptides has an antitumour effect in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Honey-bee products in prevention and/or therapy of murine transplantable tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Growth arrest and apoptosis of the human hepatocellular carcinoma cell line BEL-7402 induced by melittin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Phospholipase A2-independent Ca2+ entry and subsequent apoptosis induced by melittin in human MG63 osteosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Melittin prevents liver cancer cell metastasis through inhibition of the Rac1-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Potentiation of bleomycin lethality in HeLa and V79 cells by bee venom

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Inhibition of growth of C6 astrocytoma cells by inhibitors of calmodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: involvement of oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

A novel neurotrophic role of secretory phospholipases A2 for cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

The effect of melittin on proliferation and death of thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

The sting. Melittin forms channels in lipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

The structure of melittin in membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Comparison between complement and melittin hemolysis: anti-melittin antibodies inhibit complement lysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Template-assembled melittin: structural and functional characterization of a designed, synthetic channel-forming protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Kinetics and mechanism of hemolysis induced by melittin and by a synthetic melittin analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Pore formation and translocation of melittin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Activation of high levels of endogenous phospholipase A2 in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Possible mechanisms of action of cobra snake venom cardiotoxins and bee venom melittin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Protease inhibitors selectively block T cell receptor-triggered programmed cell death in a murine T cell hybridoma and activated peripheral T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Calmodulin and calcium-dependent protease I coordinately regulate the interaction of fodrin with actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Phospholipase A2-induced neurotoxicity in vitro and in vivo in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Melittin exerts multiple effects on the release of free fatty acids from L1210 cells: lack of selective activation of phospholipase A2 by melittin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Antimicrobial peptides in toroidal and cylindrical pores

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Antitumor action and immune activation through cooperation of bee venom secretory phospholipase A2 and phosphatidylinositol-(3,4)-bisphosphate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Mechanisms of tumor metastasis: cell biological aspects and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Tumor cell adhesion to the extracellular matrix and signal transduction mechanisms implicated in tumor cell motility, invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Bee venom suppresses PMA-mediated MMP-9 gene activation via JNK/p38 and NF-kappaB-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Melittin suppresses PMA-induced tumor cell invasion by inhibiting NF-kappaB and AP-1-dependent MMP-9 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

The cellular basis of site-specific tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Carbohydrate-mediated cell adhesion involved in hematogenous metastasis of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Bee venom inhibits tumor angiogenesis and metastasis by inhibiting tyrosine phosphorylation of VEGFR-2 in LLC-tumor-bearing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Inhibitory effect of recombinant adenovirus carrying melittin gene on hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Conjugates of lytic peptides and LHRH or betaCG target and cause necrosis of prostate cancers and metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Cationic silica nanoparticles as gene carriers: synthesis, characterization and transfection efficiency in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Antimicrobial activity of cecropins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Dextrin-phospholipase A2: synthesis and evaluation as a bioresponsive anticancer conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Selective death of human breast cancer cells by lytic immunoliposomes: Correlation with their HER2 expression level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Control of tumour vascular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Vascularization of tumors: A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Effects of a lytic peptide conjugated to beta HCG on ovarian cancer: studies in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Characteristics of the cytotoxic effects of the phenothiazine class of calmodulin antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Ki-67 as a molecular target for therapy in an in vitro three-dimensional model for ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Ki-67 protein is associated with ribosomal RNA transcription in quiescent and proliferating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Proliferation of Rous sarcoma virus-infected, but not of normal, chicken fibroblasts in a medium of reduced calcium and magnesium concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

The regulation of cell proliferation by calcium and cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Delayed oxidant-induced cell death involves activation of phospholipase A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Endonuclease G is an apoptotic DNase when released from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

NADH oxidase activity of mitochondrial apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Caspase-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Melittin induces Bcl-2 and caspase-3-dependent apoptosis through downregulation of Akt phosphorylation in human leukemic U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IkappaBalpha kinase-NFkap

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Mechanisms of bee venom-induced acute renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Bee venom secretory phospholipase A2 and phosphatidylinositol-homologues cooperatively disrupt membrane integrity, abrogate signal transduction and inhibit proliferation of renal cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

MHC class II signal transduction in human dendritic cells induced by a natural ligand, the LAG-3 protein (CD223).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Effects of imatinib on monocyte-derived dendritic cells are mediated by inhibition of nuclear factor-kappaB and Akt signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Defective dendritic cell migration and activation of adaptive immunity in PI3Kgamma-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Phosphoinositides: key players in cell signalling, in time and space.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Phosphoinositides and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Multiple ras effector pathways contribute to G(1) cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Restoration of p53 to limit tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Pharmacological reactivation of mutant p53: from protein structure to the cancer patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

p53 in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Apamin as a novel template for structure-based rational design of potent peptide activators of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Ca(2+)-activated K+ channels: molecular determinants and function of the SK family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Inhibitory effects of ganoderma lucidum on tumorigenesis and metastasis of human hepatoma cells in cells and animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Therapeutic intervention of experimental breast cancer bone metastasis by indole-3-carbinol in SCID-human mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Matrix metalloproteinases in tumor invasion: role for cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Blockade of tumor growth due to matrix metalloproteinase-9 inhibition is mediated by sequential activation of beta1-integrin, ERK, and NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Bee venom, immunostimulant or immunosuppressor? Insight into the effect on matrix metalloproteinases and interferons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Oxidized phospholipids as modulators of inflammation in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Dendritic cells and the control of immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

The danger model: a renewed sense of self

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Venom immunotherapy induces monocyte activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

Role of melittin-like region within phospholipase A(2)-activating protein in biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-011-9339-3

10.1007/S10555-011-9339-3

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference